Current Drug Targets


Francis J. Castellino
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556


Editorial [Hot topic: Control and Regulation of Permeability of MDR Bacterial Pathogens to Antibiotics Presented by COST Action BM0701 (Guest Editors: L. Amaral and J.M. Pages)] promotion: free to download

Volume:9   Issue:9
Pp: 718-718
Leonard Amaral and Jean Marie Pages
DOI: 10.2174/138945008785747815

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Structure and Mechanism of Drug Efflux Machinery in Gram Negative Bacteria

Volume:9   Issue:9
Pp: 719-728
Zbigniew Pietras, Vassiliy N. Bavro, Nicholas Furnham, Marialuisa Pellegrini-Calace, E. James Milner-White and Ben F. Luisi
DOI: 10.2174/138945008785747743

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The AcrB Efflux Pump: Conformational Cycling and Peristalsis Lead to Multidrug Resistance

Volume:9   Issue:9
Pp: 729-749
Markus A. Seeger, Kay Diederichs, Thomas Eicher, Lorenz Brandstatter, Andre Schiefner, Francois Verrey and Klaas M. Pos
DOI: 10.2174/138945008785747789

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Membrane Permeability and Regulation of Drug “Influx and Efflux” in Enterobacterial Pathogens

Volume:9   Issue:9
Pp: 750-759
Anne Davin-Regli, Jean-Michel Bolla, Chloe E. James, Jean-Philippe Lavigne, Jacqueline Chevalier, Eric Garnotel, Alexander Molitor and Jean-Marie Pages
DOI: 10.2174/138945008785747824

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Biophysical Characterization of In- and Efflux in Gram-Negative Bacteria

Volume:9   Issue:9
Pp: 789-796
Helge Weingart, Mircea Petrescu and Mathias Winterhalter
DOI: 10.2174/138945008785747752

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Promising Therapy of XDR-TB/MDR-TB with Thioridazine an Inhibitor of Bacterial Efflux Pumps

Volume:9   Issue:9
Pp: 816-819
L. Amaral, M. Martins, M. Viveiros, J. Molnar and J. E. Kristiansen
DOI: 10.2174/138945008785747798

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