Current Drug Targets

Francis J. Castellino
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556
USA

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Editorial:Brain Hemorrhages and Future Management free to download

Volume:18   Issue:12
Pp: 1315-1315
Gang Chen, Peter Lackner, Ihsan Solaroğlu and John H. Zhang
DOI: 10.2174/138945011812170824125820

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Aligning Animal Models of Clinical Germinal Matrix Hemorrhage, From Basic Correlation to Therapeutic Approach

Volume:18   Issue:12
Pp: 1316-1328
Tim Lekic, Damon Klebe, Pilar Pichon, Katarina Brankov, Sally Sultan, Devin McBride, Darlene Casel, Alhamza Al-Bayati, Yan Ding, Jiping Tang and John H. Zhang
DOI: 10.2174/1389450117666160615100538

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Early Hematoma Enlargement in Primary Intracerebral Hemorrhage

Volume:18   Issue:12
Pp: 1345-1348
Du Cao, Qi Li, Peichun Fu, John Zhang and Jun Yang
DOI: 10.2174/1389450118666170427151011

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A Therapeutic Target of Cerebral Hemorrhagic Stroke: Matrix Metalloproteinase- 9

Volume:18   Issue:12
Pp: 1358-1366
Baoqi Dang, Xiaochun Duan, Zhong Wang, Weichun He and Gang Chen
DOI: 10.2174/1389450118666170427151657

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The Double Roles of the Prostaglandin E2 EP2 Receptor in Intracerebral Hemorrhage

Volume:18   Issue:12
Pp: 1377-1385
Xu Luo, Qiquan Zhu, Jie Zhang, Qin Huang, Zongyi Xie and Yuan Cheng
DOI: 10.2174/1389450117666151209122826

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The Role of Pericytes in Neurovascular Unit: Emphasis on Stroke

Volume:18   Issue:12
Pp: 1386-1391
Ozgur Oztop-Cakmak, Ihsan Solaroglu and Yasemin Gursoy-Ozdemir
DOI: 10.2174/1389450117666160613104523

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Neuroprotective Effects of Drug-Induced Therapeutic Hypothermia in Central Nervous System Diseases

Volume:18   Issue:12
Pp: 1392-1398
Junwei Ma, Yibin Wang, Zhong Wang, Haiying Li, Zhimin Wang and Gang Chen
DOI: 10.2174/1389450118666170607104251

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Neuroinflammation is Associated with Brain Extracellular TAU-Protein Release After Spontaneous Subarachnoid Hemorrhage

Volume:18   Issue:12
Pp: 1408-1416
Alois Josef Schiefecker, Anelia Dietmann, Ronny Beer, Bettina Pfausler, Peter Lackner, Mario Kofler, Marlene Fischer, Gregor Broessner, Florian Sohm, Miriam Mulino, Claudius Thomé, Christian Humpel, Erich Schmutzhard and Raimund Helbok
DOI: 10.2174/1389450117666160201111804

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Nosocomial Infections and Antimicrobial Treatment in Coiled Patients with Aneurysmal Subarachnoid Hemorrhage

Volume:18   Issue:12
Pp: 1417-1423
Peter Lackner, Christoph Mueller, Ronny Beer, Gregor Broessner, Marlene Fischer, Raimund Helbok, Alois Schiefecker, Erich Schmutzhard and Bettina Pfausler
DOI: 10.2174/1389450117666160401124426

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Early Brain Injury or Vasospasm? An Overview of Common Mechanisms

Volume:18   Issue:12
Pp: 1424-1429
Basak Topkoru, Emrah Egemen, Ihsan Solaroglu and John H. Zhang
DOI: 10.2174/1389450117666160905112923

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Targeted Temperature Management in Spontaneous Intracerebral Hemorrhage: A Systematic Review

Volume:18   Issue:12
Pp: 1430-1440
Marlene Fischer, Alois Schiefecker, Peter Lackner, Florian Frank, Raimund Helbok, Ronny Beer, Bettina Pfausler, Erich Schmutzhard and Gregor Broessner
DOI: 10.2174/1389450117666160703161511

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Pharmacological Management Options to Prevent and Reduce Ischemic Hemorrhagic Transformation

Volume:18   Issue:12
Pp: 1441-1459
Wing Mann Ho, Cesar Reis, Onat Akyol, Gokce Yilmaz Akyol, Richard Applegate II, Gary Stier, Robert Martin and John H. Zhang
DOI: 10.2174/1389450117666160818115850

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Targeting Transient Receptor Potential Canonical Channels for Diseases of the Nervous System

Volume:18   Issue:12
Pp: 1460-1465
Yibin Wang, Jiyuan Bu, Haitao Shen, Haiying Li, Zhong Wang and Gang Chen
DOI: 10.2174/1389450117666151209120007

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