Current Drug Targets


Francis J. Castellino
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556


Meet Our Editorial Board Member: promotion: free to download

Volume:17   Issue:4
Pp: 375-375
Stefania Vetrano
DOI: 10.2174/138945011704160212092714

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Editorial (Thematic Issue: Therapeutic Modulators of Cellular Senescence: Common Targets in Cancer And Aging) free to download

Volume:17   Issue:4
Pp: 376-376
Mauro Provinciali and Marco Malavolta
DOI: 10.2174/138945011704160212093659

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Morphological and Functional Characteristic of Senescent Cancer Cells

Volume:17   Issue:4
Pp: 377-387
Ewa Sikora, Grazyna Mosieniak and Malgorzata Alicja Sliwinska
DOI: 10.2174/1389450116666151019094724

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Endothelial Cell Senescence and Inflammaging: MicroRNAs as Biomarkers and Innovative Therapeutic Tools

Volume:17   Issue:4
Pp: 388-397
Francesco Prattichizzo, Massimiliano Bonafè, Artan Ceka, Angelica Giuliani, Maria Rita Rippo, Massimo Re, Roberto Antonicelli, Antonio Domenico Procopio and Fabiola Olivieri
DOI: 10.2174/1389450116666150804105659

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Roles of Apoptosis and Cellular Senescence in Cancer and Aging

Volume:17   Issue:4
Pp: 405-415
Claudia Cerella, Cindy Grandjenette, Mario Dicato and Marc Diederich
DOI: 10.2174/1389450116666150202155915

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The Impact of the Emerging Genomics Data on the Management of Agerelated Phenotypes in the Context of Cellular Senescence

Volume:17   Issue:4
Pp: 428-438
Alberto Montesanto, Silvana Geracitano, Sabrina Garasto, Sergio Fusco, Fabrizia Lattanzio, Giuseppe Passarino and Andrea Corsonello
DOI: 10.2174/1389450116666150120103329

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Pleiotropic Effects of Tocotrienols and Quercetin on Cellular Senescence: Introducing the Perspective of Senolytic Effects of Phytochemicals

Volume:17   Issue:4
Pp: 447-459
Marco Malavolta, Elisa Pierpaoli, Robertina Giacconi, Laura Costarelli, Francesco Piacenza, Andrea Basso, Maurizio Cardelli and Mauro Provinciali
DOI: 10.2174/1389450116666150907105104

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Is Senescence Reversible?

Volume:17   Issue:4
Pp: 460-466
Shweta Chakradeo, Lynne W. Elmore and David A. Gewirtz
DOI: 10.2174/1389450116666150825113500

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The Key Role of Canonical Wnt/β-catenin Signaling in Cartilage Chondrocytes

Volume:17   Issue:4
Pp: 475-484
Xiaoliang Yuan, Haiqing Liu, Hao Huang, Hai Liu, Linfu Li, Jianqiong Yang, Weimei Shi, Weiyou Liu and Longhuo Wu
DOI: 10.2174/1389450116666150825112623

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