Current Drug Targets


Francis J. Castellino
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556


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Editorial (Hot Topic: Novel Techniques as a Tool to Investigate on the Triggering of Biological Targets) promotion: free to download

Volume:14   Issue: 9
Pp: 937-937
Marcello Locatelli
DOI: 10.2174/1389450111314090001

Strategies for Developing Tuberculosis Vaccines: Emerging Approaches

Volume:14   Issue: 9
Pp: 938-951
Adriano Mollica, Azzurra Stefanucci and Roberto Costante
DOI: 10.2174/1389450111314090002

Structural Systems Pharmacology: A New Frontier in Discovering Novel Drug Targets

Volume:14   Issue: 9
Pp: 952-958
Hepan Tan, Xiaoxia Ge and Lei Xie
DOI: 10.2174/1389450111314090003

Phytochemistry and Pharmacognosy of Naturally Occurring Prenyloxyanthraquinones

Volume:14   Issue: 9
Pp: 959-963
Francesco Epifano, Serena Fiorito, Giuseppe Carlucci, Marcello Locatelli and Salvatore Genovese
DOI: 10.2174/1389450111314090004

Yeast as a Biosensor of Detoxification: A Tool for Identifying New Compounds that Revert Multidrug Resistance

Volume:14   Issue: 9
Pp: 964-985
Carmen Martín-Cordero, Angeles Sanchez-Pico, Antonio J. Leon-Gonzalez, Antonio J. Perez-Pulido and Rafael R. Daga
DOI: 10.2174/1389450111314090005

Antimicrobial Activity of Willowherb (Epilobium angustifolium L.) Leaves and Flowers

Volume:14   Issue: 9
Pp: 986-991
Ivan Kosalec, Nevenka Kopjar and Dario Kremer
DOI: 10.2174/13894501113149990177

Hydroxytyrosol Expresses Antifungal Activity In Vitro

Volume:14   Issue: 9
Pp: 992-998
Natasa Zoric, Igor Horvat, Nevenka Kopjar, Ante Vucemilovic, Dario Kremer, Sinisa Tomic and Ivan Kosalec
DOI: 10.2174/13894501113149990167

Enhanced Antioxidant and Protective Activities on Retinal Ganglion Cells of Carotenoids-Overexpressing Transgenic Carrot

Volume:14   Issue: 9
Pp: 999-1005
Kee Dong Yoon, Suk-Nam Kang, Ji-Yeong Bae, Haeng-Soon Lee, Sang-Soo Kwak, Insurk Jang, Il-Suk Kim, Cheol Ho Lee, Jung Myung Bae, Shin Woo Lee and Mi-Jeong Ahn
DOI: 10.2174/1389450111314090008

Investigation of Chemical Compounds, Antioxidant and Antimicrobial Properties of Teucrium arduini L. (Lamiaceae)

Volume:14   Issue: 9
Pp: 1006-1014
Dario Kremer, Iztok Joze Kosir, Ivan Kosalec, Marijana Zovko Koncic, Tanja Potocnik, Andreja Cerenak, Nada Bezic, Sinisa Srecec and Valerija Dunkic
DOI: 10.2174/1389450111314090009

Photodynamic Inactivation of Yeast and Bacteria by Extracts of Alternanthera brasiliana

Volume:14   Issue: 9
Pp: 1015-1022
Nathalia L. Andreazza, Caroline C. de Lourenco, Carlos A. T. Siqueira, Alexandra C.H.F. Sawaya, Tadia F. Lapinski, Adriana Gasparetto, Sonia Khouri, Stella R. Zamuner, Egberto Munin and Marcos Jose Salvador
DOI: 10.2174/1389450111314090010

Application of Pyrolysis-Gas Chromatography-Mass Spectrometry and Multivariate Analysis to Study Bacteria and Fungi in Biofilms Used for Bioremediation

Volume:14   Issue: 9
Pp: 1023-1033
Dora Melucci, Stefano Fedi, Marcello Locatelli, Clinio Locatelli, Simona Montalbani and Martina Cappelletti
DOI: 10.2174/1389450111314090011

Advances in the Targeting Molecules Modified Chitosan-Based Nanoformulations

Volume:14   Issue: 9
Pp: 1034-1052
Hongliang Du, Xiaoqing Cai and Guangxi Zhai
DOI: 10.2174/1389450111314090012

Differential Scanning Calorimetry as a Tool to Investigate the Transfer of Anticancer Drugs to Biomembrane Model

Volume:14   Issue: 9
Pp: 1053-1060
Maria Grazia Sarpietro, Maria Lorena Accolla, Christian Celia, Alessandro Grattoni, Francesco Castelli, Massimo Fresta, Mauro Ferrari and Donatella Paolino
DOI: 10.2174/1389450111314090013

Validated RP-HPLC Method for the Simultaneous Analysis of Gemcitabine and LY-364947 in Liposomal Formulations

Volume:14   Issue: 9
Pp: 1061-1069
Shyam S. Bansal, Christian Celia, Silvia Ferrati, Erika Zabre, Mauro Ferrari, Ganesh Palapattu and Alessandro Grattoni
DOI: 10.2174/13894501113149990165

Niosomes Encapsulating Ibuprofen–Cyclodextrin Complexes: Preparation and Characterization

Volume:14   Issue: 9
Pp: 1070-1078
Carlotta Marianecci, Federica Rinaldi, Sara Esposito, Luisa Di Marzio and Maria Carafa
DOI: 10.2174/1389450111314090015