Current Drug Targets


Francis J. Castellino
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556


Editorial [Hot topic: Central and Peripheral Metabolic Changes in Neurodegenerative Diseases (Guest Editor: Ana Cristina Rego)] promotion: free to download

Volume:11   Issue:10
Pp: 1192-1192
Ana Cristina Rego
DOI: 10.2174/1389450111007011192

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Multiple Defects in Energy Metabolism in Alzheimers Disease

Volume:11   Issue:10
Pp: 1193-1206
I. L. Ferreira, R. Resende, E. Ferreiro, A. C. Rego and C. F. Pereira
DOI: 10.2174/1389450111007011193

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Metabolic Aspects of Prion Diseases: An Overview

Volume:11   Issue:10
Pp: 1207-1217
Tanja Vranac and Mara Bresjanac
DOI: 10.2174/1389450111007011207

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Hypothalamic and Neuroendocrine Changes in Huntingtons Disease

Volume:11   Issue:10
Pp: 1237-1249
Sofia Hult, Kristofer Schultz, Rana Soylu and Asa Petersen
DOI: 10.2174/1389450111007011237

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The Role of PGC-1α in the Pathogenesis of Neurodegenerative Disorders

Volume:11   Issue:10
Pp: 1262-1269
Krisztina Rona-Voros and Patrick Weydt
DOI: 10.2174/1389450111007011262

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Sirtuins: Common Targets in Aging and in Neurodegeneration

Volume:11   Issue:10
Pp: 1270-1280
Rita Machado de Oliveira, Teresa F. Pais and Tiago Fleming Outeiro
DOI: 10.2174/1389450111007011270

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Editorial [Targeting Genetic Instability in Cancer Cells (Guest Editor: Francesco Colotta)] promotion: free to download

Volume:11   Issue:10
Pp: 1293-1295
Francesco Colotta
DOI: 10.2174/1389450111007011293

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The Mutator Phenotype in Cancer: Molecular Mechanisms and Targeting Strategies

Volume:11   Issue:10
Pp: 1296-1303
Marc J. Prindle, Edward J. Fox and Lawrence A. Loeb
DOI: 10.2174/1389450111007011296

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Genetic and Epigenetic Heterogeneity in Cancer: The Ultimate Challenge for Drug Therapy

Volume:11   Issue:10
Pp: 1304-1316
H. H. Heng, G. Liu, J. B. Stevens, S. W. Bremer, K. J. Ye and C. J. Ye
DOI: 10.2174/1389450111007011304

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Targeting Synthetic Lethality in DNA Damage Repair Pathways as an Anti-Cancer Strategy

Volume:11   Issue:10
Pp: 1336-1340
Benjamin J. Moeller, Wadih Arap and Renata Pasqualini
DOI: 10.2174/1389450111007011336

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