Abstract
Cell Transplantation is one of the powerful tools to ameliorate the capillary flow in ischemic condition. EPC (Endothelial Progenitor Cell) was identified in adult peripheral blood and thought to be a suitable candidate for cell transplantation. Also, gene therapy is already promising choice for enhancing angiogenic property. The combination of cell transplantation and gene therapy should be more effective way to regenerate vasculature in ischemic region. Recently, several research reports have come out regarding gene modified cell transplantation. We will mainly focus on the background of EPC, and then gene modified EPC findings in this review.
Keywords: Endothelial Progenitor Cell (EPC), Gene modified cell therapy, VEGF, TERT, Vasculogenesis
Current Gene Therapy
Title: Gene Modified Cell Transplantation for Vascular Regeneration
Volume: 7 Issue: 1
Author(s): Satoshi Murasawa and Takayuki Asahara
Affiliation:
Keywords: Endothelial Progenitor Cell (EPC), Gene modified cell therapy, VEGF, TERT, Vasculogenesis
Abstract: Cell Transplantation is one of the powerful tools to ameliorate the capillary flow in ischemic condition. EPC (Endothelial Progenitor Cell) was identified in adult peripheral blood and thought to be a suitable candidate for cell transplantation. Also, gene therapy is already promising choice for enhancing angiogenic property. The combination of cell transplantation and gene therapy should be more effective way to regenerate vasculature in ischemic region. Recently, several research reports have come out regarding gene modified cell transplantation. We will mainly focus on the background of EPC, and then gene modified EPC findings in this review.
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Cite this article as:
Murasawa Satoshi and Asahara Takayuki, Gene Modified Cell Transplantation for Vascular Regeneration, Current Gene Therapy 2007; 7 (1) . https://dx.doi.org/10.2174/1566523210707010001
DOI https://dx.doi.org/10.2174/1566523210707010001 |
Print ISSN 1566-5232 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5631 |
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