Combinatorial Chemistry & High Throughput Screening

Rathnam Chaguturu 
iDDPartners, 3 Edith Court
Princeton Junction
NJ 08550
USA

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Open Access Articles

High Throughput Screening of Esterases, Lipases and Phospholipases in Mutant and Metagenomic Libraries: A Review open Access plus

Volume: 19   Issue: 8
Pp: 605-615
Carlina Peña-García, Mónica Martínez-Martínez, Dolores Reyes-Duarte and Manuel Ferrer
DOI:10.2174/1386207319666151110123927

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An In-Silico Investigation of Phytochemicals as Antiviral Agents Against Dengue Fever open Access plus

Volume: 19   Issue: 7
Pp: 516-536
Chelsea N. Powers and William N. Setzer
DOI:10.2174/1386207319666160506123715

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Identification of Protein Palmitoylation Inhibitors from a Scaffold Ranking Library open Access plus

Volume: 19   Issue: 4
Pp: 262-274
Laura D. Hamel, Brian J. Lenhart, David A. Mitchell, Radleigh G. Santos, Marc A. Giulianotti and Robert J. Deschenes
DOI:10.2174/1386207319666160324123844

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Discovery of MINC1, a GTPase-Activating Protein Small Molecule Inhibitor, Targeting MgcRacGAP open Access plus

Volume: 18   Issue: 1
Pp: 3-17
Arjan J. van Adrichem, Annika Fagerholm, Laura Turunen, Anna Lehto, Jani Saarela, Ari Koskinen, Gretchen A. Repasky and Krister Wennerberg
DOI:10.2174/1386207318666141205112730

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Digital Holographic Microscopy: A Quantitative Label-Free Microscopy Technique for Phenotypic Screening open Access plus

Volume: 17   Issue: 1
Pp: 80-88
Benjamin Rappaz, Billy Breton, Etienne Shaffer and Gerardo Turcatti
DOI:10.2174/13862073113166660062

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Chemical Informatics and the Drug Discovery Knowledge Pyramid open Access plus

Volume: 16   Issue: 10
Pp: 764-776
Gerald H. Lushington, Yinghua Dong and Bhargav Theertham
DOI:10.2174/1386207311301010006

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A Generalized Model and High Throughput Data Analysis System for Functional Modulation of Receptor-Agonist Systems Suitable for use in Drug Discovery open Access plus

Volume: 16   Issue: 3
Pp: 199-209
Aaron C. Pawlyk, R. Kyle Palmer, Dennis Sprous and Chip Allee
DOI:10.2174/1386207311316030005

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A Simple Method for Analyzing Actives in Random RNAi Screens: Introducing the “H Score” for Hit Nomination & Gene Prioritization open Access plus

Volume: 15   Issue: 9
Pp: 686-704
Bhavneet Bhinder and Hakim Djaballah
DOI:10.2174/138620712803519671

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Application of NMR Metabolomics to Search for Human Disease Biomarkers open Access plus

Volume: 15   Issue: 8
Pp: 595-610
Teklab Gebregiworgis and Robert Powers
DOI:10.2174/138620712802650522

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Editorial [Hot topic: Using Bioluminescent Assays as Quantitative Cell-Based and Biochemical Biosensors (Guest Editor: John Watson)] open Access plus

Volume: 14   Issue: 8
Pp: 645-647
John Watson
DOI:10.2174/138620711796504406

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Alternative Medicine Safety: Agaricus blazei and Propolis open Access plus

Volume: 14   Issue: 7
Pp: 616-621
Kenji Sorimachi and Takaaki Nakamoto
DOI:10.2174/138620711796367238

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The Design and Application of Target-Focused Compound Libraries open Access plus

Volume: 14   Issue: 6
Pp: 521-531
C. John Harris, Richard D. Hill, David W. Sheppard, Martin J. Slater and Pieter F.W. Stouten
DOI:10.2174/138620711795767802

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Two Panels of Steroid Receptor Luciferase Reporter Cell Lines for Compound Profiling open Access plus

Volume: 14   Issue: 4
Pp: 248-266
David Sedlak, Aileen Paguio and Petr Bartunek
DOI:10.2174/138620711795222446

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Building a Tiered Approach to In Vitro Predictive Toxicity Screening: A Focus on Assays with In Vivo Relevance open Access plus

Volume: 13   Issue: 2
Pp: 188-206
James M. McKim Jr.
DOI:10.2174/138620710790596736

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Generating ‘Omic Knowledge’: The Role of Informatics in High Content Screening open Access plus

Volume: 12   Issue: 9
Pp: 917-925
Mark A. Collins
DOI:10.2174/138620709789383259

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Applications of High Content Screening in Life Science Research open Access plus

Volume: 12   Issue: 9
Pp: 870-876
Joseph M. Zock
DOI:10.2174/138620709789383277

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Combinatorics of Reaction-Network Posets open Access plus

Volume: 11   Issue: 9
Pp: 723-733
Douglas J. Klein, Teodora Ivanciuc, Anton Ryzhov and Ovidiu Ivanciuc
DOI:10.2174/138620708786306050

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Machine Learning for In Silico Virtual Screening and Chemical Genomics: New Strategies open Access plus

Volume: 11   Issue: 8
Pp: 677-685
Jean-Philippe Vert and Laurent Jacob
DOI:10.2174/138620708785739899

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Fluorescent Probes for Cellular Assays open Access plus

Volume: 11   Issue: 7
Pp: 505-513
George T. Hanson and Bonnie J. Hanson
DOI:10.2174/138620708785204090

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Label-Free Cell-Based Assays for GPCR Screening open Access plus

Volume: 11   Issue: 5
Pp: 357-369
Ye Fang, Anthony G. Frutos and Ronald Verklereen
DOI:10.2174/138620708784534789

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Pharmacological Characterization of Ligands at Recombinant NMDA Receptor Subtypes by Electrophysiological Recordings and Intracellular Calcium Measurements open Access plus

Volume: 11   Issue: 4
Pp: 304-315
Kasper B. Hansen, Hans Brauner-Osborne and Jan Egebjerg
DOI:10.2174/138620708784246040

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Back to Basics: Label-Free Technologies for Small Molecule Screening open Access plus

Volume: 11   Issue: 3
Pp: 231-237
Andrew K. Shiau, Mark E. Massari and Can C. Ozbal
DOI:10.2174/138620708783877807

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Discovery of Novel Targets with High Throughput RNA Interference Screening open Access plus

Volume: 11   Issue: 3
Pp: 175-184
Paul D. Kassner
DOI:10.2174/138620708783877744

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High Throughput Screening of Gene Functions in Mammalian Cells Using Reversely Transfected Cell Arrays: Review And Protocol open Access plus

Volume: 11   Issue: 2
Pp: 159-172
Michael Sturzl, Andreas Konrad, Gaby Sander, Effi Wies, Frank Neipel, Elisabeth Naschberger, Simone Reipschlager, Nathalie Gonin-Laurent, Raymund E. Horch, Ulrich Kneser, Werner Hohenberger, Holger Erfle and Mathias Thurau
DOI:10.2174/138620708783744499

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Yeast Genomics and Drug Target Identification open Access plus

Volume: 10   Issue: 8
Pp: 618-634
Nike Bharucha and Anuj Kumar
DOI:10.2174/138620707782507340

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