Combinatorial Chemistry & High Throughput Screening

Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research


Gerald H. Lushington
LiS Consulting, Lawrence


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Protein Kinase Substrate Profiling with a High-Density Peptide Microarray

Volume:13   Issue: 9
Pp: 777-789
Xiaoming Han, Tatsuhiko Sonoda, Takeshi Mori, Go Yamanouchi, Takayuki Yamaji, Syuhei Shigaki, Takuro Niidome and Yoshiki Katayama
DOI: 10.2174/138620710792927402

Identification of Novel Scaffolds for IκB Kinase Beta Inhibitor via a High Throughput Screening TR-FRET Assay

Volume:13   Issue: 9
Pp: 790-797
Kwang-Seok Oh, Sunghou Lee, Joong Kwon Choi and Byung Ho Lee
DOI: 10.2174/138620710792927367

Discovery of Novel Cell Proliferation-Enhancing Gene by Random siRNA Library Based Combinatorial Screening

Volume:13   Issue: 9
Pp: 798-806
Xiahui Xiong, Yabin Lu, Lishu Zhang, Bo Wang, Yingtao Zhao, Xiu-Jie Wang, Xiaofang Huo, Yan Shen, Zicai Liang and Meihong Chen
DOI: 10.2174/138620710792927420

A Novel Directed Evolution Method to Enhance Cell-Type Specificity of Adeno-Associated Virus Vectors

Volume:13   Issue: 9
Pp: 807-812
Stephan Marsch, Anke Huber, Michael Hallek, Hildegard Buning and Luca Perabo
DOI: 10.2174/138620710792927385

Synthesis of Functionalized Chromenes from Meldrum’s Acid, 4- Hydroxycoumarin, and Ketones or Aldehydes

Volume:13   Issue: 9
Pp: 813-817
Maryam Sabbaghan, Issa Yavari and Zinatossadat Hossaini
DOI: 10.2174/138620710792927358

Validation of a Phage Display Method for Protease Inhibitor Selection Using SFTI and HiTI Synthetic Hybrid Peptides

Volume:13   Issue: 9
Pp: 829-835
Renato de Marco, Simone S. Azzolini, Diogo V. Lovato, Ricardo J.S. Torquato, Rogerio Amino, Antonio de Miranda and Aparecida S. Tanaka
DOI: 10.2174/138620710792927394