Combinatorial Chemistry & High Throughput Screening

Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research


Gerald H. Lushington
LiS Consulting, Lawrence


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Directed Evolution Toward Improved Production of L-Ribose from Ribitol

Volume:13   Issue: 4
Pp: 302-308
Trevor N. Christ, Kara A. Deweese and Ryan D. Woodyer
DOI: 10.2174/138620710791054277

High Throughput Bioassays Using Nanoparticles

Volume:13   Issue: 4
Pp: 309-317
Agustina Gomez-Hens, Juan M. Fernandez-Romero and Maria P. Aguilar-Caballos
DOI: 10.2174/138620710791054240

High Throughput Discovery of Families of High Activity WGS Catalysts: Part I - History and Methodology

Volume:13   Issue: 4
Pp: 318-330
Karin Yaccato, Ray Carhart, Alfred Hagemeyer, Michael Herrmann, Andreas Lesik, Peter Strasser, Anthony Volpe, Howard Turner, Henry Weinberg, Robert K. Grasselli, Christopher J. Brooks and John M. Pigos
DOI: 10.2174/138620710791054286

High Throughput Calorimetry for Evaluating Enzymatic Reactions Generating Phosphate

Volume:13   Issue: 4
Pp: 331-336
Lieve Hoflack, Manu De Groeve, Tom Desmet, Peter Van Gerwen and Wim Soetaert
DOI: 10.2174/138620710791054268

Design, Synthesis and Biological Evaluation of a Library of Thiocarbazates and Their Activity as Cysteine Protease Inhibitors

Volume:13   Issue: 4
Pp: 337-351
Zhuqing Liu, Michael C. Myers, Parag P. Shah, Mary Pat Beavers, Phillip A. Benedetti, Scott L. Diamond, Amos B. Smith,III and Donna M. Huryn
DOI: 10.2174/138620710791054303

Coupling the Inhibition of Viral Transduction with a Positive Fluorescence Signal

Volume:13   Issue: 4
Pp: 352-357
Jenifer Clausell-Tormos, Andrew D. Griffiths and Christoph A. Merten
DOI: 10.2174/138620710791054312

Fluorescent Substrates Useful as High Throughput Screening Tools for ADAM9

Volume:13   Issue: 4
Pp: 358-365
Marcia L. Moss, Fred H. Rasmussen, Raphael Nudelman, Peter J. Dempsey and Jason Williams
DOI: 10.2174/138620710791054259

MoStBioDat – Molecular and Structural Bioinformatics Database

Volume:13   Issue: 4
Pp: 366-374
Andrzej Bak, Jaroslaw Polanski, Thomas Stockner and Agata Kurczyk
DOI: 10.2174/138620710791054295