Combinatorial Chemistry & High Throughput Screening

Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research

Editor-in-Chief:

Gerald H. Lushington
LiS Consulting, Lawrence
KS
USA

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Editorial [Hot Topic: GPCR High Throughput Screening (Part 1) (Guest Editors: David P. Siderovski and Francis S. Willard)] promotion: free to download

Volume:11   Issue: 5
Pp: 336-336
Francis S. Willard and David P. Siderovski
DOI: 10.2174/138620708784534815

Functional Selectivity in GPCR Modulator Screening

Volume:11   Issue: 5
Pp: 337-343
Terry Kenakin
DOI: 10.2174/138620708784534824

Label-Free Cell-Based Assays for GPCR Screening open access plus

Volume:11   Issue: 5
Pp: 357-369
Ye Fang*, Anthony G. Frutos and Ronald Verklereen
DOI: 10.2174/138620708784534789

State-Selective Binding Peptides for Heterotrimeric G-Protein Subunits:Novel Tools for Investigating G-Protein Signaling Dynamics

Volume:11   Issue: 5
Pp: 370-381
Christopher A. Johnston, Francis S. Willard, J. Kevin Ramer, Rainer Blaesius, C. Natalia Roques and David P. Siderovski
DOI: 10.2174/138620708784534798

G Protein β γ Subunits as Targets for Small Molecule Therapeutic Development

Volume:11   Issue: 5
Pp: 382-395
Alan V. Smrcka, David M. Lehmann and Axel L. Dessal
DOI: 10.2174/138620708784534761

A High Throughput Fluorescence Polarization Assay for Inhibitors of the GoLoco Motif/G-alpha Interaction

Volume:11   Issue: 5
Pp: 396-409
Adam J. Kimple, Adam Yasgar, Mark Hughes, Ajit Jadhav, Francis S. Willard, Robin E. Muller, Christopher P. Austin, James Inglese, Gordon C. Ibeanu, David P. Siderovski and Anton Simeonov
DOI: 10.2174/138620708784534770