Current Cancer Drug Targets

Editor-in-Chief:

Ruiwen Zhang
Center for Drug Discovery
University of Houston
3455 Cullen Blvd.
Houston, TX 77204
USA

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Ahead of Print Article(s)

Novel Homeodomain Transcription Factor Nkx2.2 in the Brain Tumor Development

Volume:18
Mubeena PM Mariyath, Mehdi Hayat Shahi*, Shirin Farheen, Mohd Tayyab, Nabeela Khanam and Asif Ali

SOCS6 Functions as a Tumor Suppressor by Inducing Apoptosis and Inhibiting Angiogenesis in Human Prostate Cancer

Volume:18
Dongbo Yuan*, Wei Wang*, Jiaming Su*, Yongqiang Zhang, Boshi Luan, Haofu Rao, Tianfei Cheng, Wei Zhang, Shiwei Xiao, Mingsheng Zhang, Fu-Neng Jiang, Zhaolin Sun, Zhenyu Jia, Wei-De Zhong and Jianguo Zhu

Antibody Based EpCAM Targeted Therapy of Cancer, Review and Update

Volume:18
Shirin Eyvazi, Safar Farajnia*, Siavoush Dastmalchi, Farzad Kanipour, Habib Zarredar and Mojgan Bandehpour

Molecular Mechanisms of Resistance in Testicular Germ Cell Tumors - Clinical Implications

Volume:18
Katarina Kalavska, Vincenza Conteduca, Ugo De Giorgi and Michal Mego*

Anticancer Properties of Essential Oils: An Overview

Volume:18
Milene Aparecida Andrade, Mariana Aparecida Braga, Pedro Henrique Souza Cesar, Marcus Vinicius Cardoso Trento, Mariana Araujo Esposito and Lucilene Fernandes Silva*

Targeting FGFR with BGJ398 in Breast Cancer: Effect on Tumor Growth and Metastasis

Volume:18
Ana Sahores, Maria May, Gonzalo Sequeira, Cynthia Fuentes, Britta Jacobsen, Claudia Lanari and Caroline Ana Lamb*

Towards Prevention of Ovarian Cancer

Volume:18
Aus Tariq Ali*

Role of Glioma-associated GLI1 Oncogene in Carcinogenesis and Cancertargeted Therapy

Volume:18
Jie Wu, Dingxin Di, Chen Zhao, Yingyi Liu, Hongxia Chen, Yan Gong, Xianda Zhao and Honglei Chen*

Tunneling Nanotubes: A Versatile Target for Cancer Therapy

Volume:18
Pragyaparamita Sahoo, Soumya Ranjan Jena and Luna Samanta*

AR Copy Number and AR Signaling-directed Therapies in Castrationresistant Prostate Cancer

Volume:17
Samanta Salvi*, Vincenza Conteduca, Cristian Lolli, Sara Testoni, Valentina Casadio, Andrea Zaccheroni, Lorena Rossi, Salvatore Luca Burgio, Cecilia Menna, Giuseppe Schepisi and Ugo De Giorgi

A High-throughput Quantitative Expression Analysis of Cancer-related Genes in Human HepG2 Cells in Response to Limonene, a Potential Anticancer Agent

Volume:17
Rand R. Hafidh*, Saba Z. Hussein, Mohammed Q. MalAllah, Ahmed S. Abdulamir and Fatimah Abu Bakar

Chemosensitizing Activity of Histone Deacetylases Inhibitory Cyclic Hydroxamic Acids for Combination Chemotherapy of Lymphatic Leukemia

Volume:17
Denis V. Mishchenko, Margarita E. Neganova, Elena N. Klimanova, Tatyana E. Sashenkova, Elena F. Shevtsova, Igor V. Vystorop, Vadim V. Tarasov, Ghulam Md Ashraf , Nagendra Sastry Yarla and Gjumrakch Aliev*

Cancer Targeted Therapy Strategy: The Pathologist’s Perspectives

Volume:18
Lara Alessandrini, Tiziana Perin, Shahin Kadare, Lino del Pup, Lorenzo Memeo, Agostino Steffan, Lorenzo Colarossi, Massimiliano Berretta, Paolo De Paoli and Vincenzo Canzonieri*

Autophagy as a Potential Therapeutic Target in Breast Cancer Treatment

Volume:17
Natalia Lisiak*, Ewa Toton and Maria Rybczynska

Diallyl Disulfide Inhibits Breast Cancer Stem Cell Progression and Glucose Metabolism by Targeting CD44/PKM2/AMPK Signaling

Volume:17
Xinhua Xie, Xiaojia Huang, Hailin Tang, Feng Ye, Lu Yang, Xiaofang Guo, Zhi Tian, Cheng Peng* and Xiaoming Xie*

Degradation of Androgen Receptor through Small Molecules for Prostate Cancer

Volume:17
Raoling Ge, Xi Xu, Pengfei Xu, Lei Li, Zhiyu Li* and Jinlei Bian

Oxidative Stress and Cancer: The Role of Nrf2

Volume:17
Sajadimajd Soraya and Khazaei Mozafar*

Development of Drug Targeting and Delivery in Cervical Cancer

Volume:17
Urvashi Aggarwal, Amit Kumar Goyal and Goutam Rath*

Ponatinib: A Review of Efficacy and Safety

Volume:17
Fulvio Massaro, Matteo Molica and Massimo Breccia*

Neoisoliquiritigenin Inhibits Tumor Progression by Targeting GRP78-β- catenin Signaling in Breast Cancer

Volume:17
Hailin Tang*, Fu Peng, Xiaojia Huang, Xinhua Xie, Bo Chen, Jiangang Shen, Fei Gao, Jieshu You, Xiaoming Xie and Jianping Chen

Involvement of CD24 in Multiple Cancer Related Pathways Makes It an Interesting New Target for Cancer Therapy

Volume:17
Shirin Eyvazi, Bahram Kazemi, Siavoush Dastmalchi* and Mojgan Bandehpour*

Clinical Evidence on the Magnitude of Change in Growth Pathway Activity in Relation to Tamoxifen Resistance is Required

Volume:17
Sepideh Mansouri, Leila Farahmand, Azin Teymourzadeh and Keivan Majidzadeh-A*

Aldose Reductase Inhibitor, Fidarestat Prevents High-fat Diet-induced Intestinal Polyps in ApcMin/+ Mice

Volume:17
Ashish Saxena, Ravinder Tammali, Kota V Ramana and Satish K. Srivastava*

Evaluation of Anti-cancer Activity of Stilbene and Methoxydibenzo[b,f] oxepin Derivatives

Volume:17
Damian Garbicz , Damian Mielecki , Michał Wrzesiński , Tomasz Pilżys, Michał Marcinkowski , Jan Piwowarski , Janusz Dębski, Ewelina Palak, Przemysław Szczeciński, Hanna Krawczyk and Elżbieta Grzesiuk*

An Update on Circumventing Multidrug Resistance in Cancer by Targeting P-Glycoprotein

Volume:17
Xiaoqian Yang, Xiaoduan Li, Zhenfeng Duan and Xipeng Wang*

The Structural Bioinformatics Analysis of Biophenolic Lignan-Estrogen Receptor Interaction

Volume:17
Farzaneh Mohamadyar-Toupkanlou*, Mina Esfandiari, Mahshid Sadat Kashef-Saberi, Mahboubeh Kabiri Renani and Masoud Soleimani

Cell-derived Exosomes as Promising Carriers for Drug Delivery and Targeted Therapy

Volume:17
Xinyi Wang*, Haiyang Zhang, Haiou Yang, Ming Bai, Tao Ning, Shuang Li, Jialu Li, Ting Deng, Guoguang Ying and Yi Ba

Recent Updates on the Therapeutic Potential of HER2 Tyrosine Kinase Inhibitors for the Treatment of Breast Cancer

Volume:17
Heena Singla, Anjana Munshi*, Raja Paramjit Singh Banipal and Vinod Kumar*

p53-Mdm2 Interaction Inhibitors as Novel Nongenotoxic Anticancer Agents

Volume:17
Surendra Kumar Nayak*, Gopal L. Khatik, Rakesh Narang, Vikramdeep Monga and Harish Kumar Chopra

Therapeutic Approaches for the Treatment of Epidermal Growth Factor Receptor Mutated Lung Cancer

Volume:17
Dhaval Sanchala, Lokesh K Bhatt* and Kedar S Prabhavalkar

Synthetic Lethality: From Research to Precision Cancer Nanomedicine

Volume:17
Anuradha Gupta, Anas Ahmad, Aqib Iqbal Dar and Rehan Khan*

Regulation of MicroRNAs by Phytochemicals: A Promising Strategy for Cancer Chemoprevention

Volume:17
Sadegh Babashah*, Babak Bakhshinejad, Maryam Tahmasebi Birgani , Katayoon Pakravan and William C Cho*

Significant Role of MUC1 in Development of Resistance to Currently Existing Anti-cancer Therapeutic Agents

Volume:17
Leila Farahmand, Parnaz Merikhian, Neda Jalili, Behrad Darvishi and Keivan Majidza*

Oncolytic Tanapoxvirus Expressing Interleukin-2 is Capable of Inducing the Regression of Human Melanoma Tumors in the Absence of T Cells

Volume:17
Tiantian Zhang, Dennis H Kordish, Yogesh R Suryawanshi, Rob R Eversole, Steven Kohler, Charles D Mackenzie and Karim Essani*

Fertility Drugs and Ovarian Cancer

Volume:17
Aus Tariq Ali*

Specific Targeting of HER2-Positive Head and Neck Squamous Cell Carcinoma Line HN5 by Idarubicin-ZHER2 Affibody Conjugate

Volume:17
Marzieh Ghanemi, Aminollah Pourshohod, Mohammad Ali Ghaffari , Alireza kheirollah, Mansour Amin, Majid Zeinali* and Mostafa Jamalan*

CX-4945, a Selective Inhibitor of Casein Kinase 2, Synergizes with B Cell Receptor Signaling Inhibitors in Inducing Diffuse Large B Cell Lymphoma Cell Death

Volume:17
Elisa Mandato, Sara Canovas Nunes, Fortunato Zaffino, Alessandro Casellato, Paolo Macaccaro, Laura Quotti Tubi, Andrea Visentin, Livio Trentin, Gianpietro Semenzato and Francesco Piazza*

The Role of Target Therapy in the Treatment of Gastrointestinal Non Colorectal Cancers: Clinical Impact and Cost Consideration

Volume:17
Massimiliano Berretta, Raffaele Di Francia, Chiara De Diviitis, Guglielmo Nasti, Vincenzo Canzonieri, Michele Caraglia, Gaetano Facchini and Umberto Tirelli

The Real Impact of Target Therapy in Breast Cancer Patients: Between Hope and Reality

Volume:17
Sebastiano Bordonaro, Massimiliano Berretta, Antonino Carmelo Tralongo, Silvia Clementi, Brigida Stanzione and Paolo Tralongo

Current and Emerging Treatments for Metastatic Renal Cell Carcinoma

Volume:17
Carla Cavaliere, Carmine D`Aniello, Chiara Della Pepa, Salvatore Pisconti, Massimiliano Berretta and Gaetano Facchini

Optimal Management of Prostate Cancer Based on its Natural Clinical History

Volume:17
Gaetano Facchini, Francesco Perri, Gabriella Misso, Carmine D`Aniello, Giuseppina Della Vittoria Scarpati, Sabrina Rossetti, Chiara Della Pepa, Salvatore Pisconti, Gerhard Unteregger, Alessia Cossu, Michele Caraglia, Massimiliano Berretta and Carla Cavaliere

Metastatic Colorectal Cancer: Role of Target Therapies and Future Perspectives

Volume:17
Anna Nappi, Massimiliano Berretta, Carmela Romano, Salvatore Tafuto, Antonino Cassata, Rossana Casaretti, Lucrezia Silvestro, Chiara De Divitiis, Lara Alessandrini, Francesco Fiorica, Alessandro Ottaiano and Guglielmo Nasti

Melanoma Adjuvant Treatment: Current Insight and Clinical Features

Volume:17
Carmine D`Aniello, Francesco Perri, Giuseppina Della Vittoria Scarpati, Chiara Della Pepa, Salvatore Pisconti, Vincenzo Montesarchio, Nicolas Wernert, Mayra Rachele Zarone, Michele Caraglia, Gaetano Facchini, Massimiliano Berretta and Carla Cavaliere

Pharmacological Profile and Pharmacogenomics of Anti-Cancer Drugs Used for Targeted Therapy

Volume:17
Raffaele Di Francia, Angela De Monaco, Mariangela Saggese, Giancarla Iaccarino, Stefania Crisci, Ferdinando Frigeri, Rosaria De Filippi, Massimiliano Berretta and Antonio Pinto