Current Cancer Drug Targets


Ruiwen Zhang
Center for Drug Discovery
University of Houston
3455 Cullen Blvd.
Houston, TX 77204


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Preface [Hot topic:Hsp90 Molecular Chaperone Inhibitors: Opportunities and Challenges (Guest Editor: Paul Workman)] promotion: free to download

Volume:3   Issue: 5
Pp: i-i
Paul Workman
DOI: 10.2174/1568009033481840

Overview: Translating Hsp90 Biology into Hsp90 Drugs

Volume:3   Issue: 5
Pp: 297-300
Paul Workman
DOI: 10.2174/1568009033481868

Structure and Functional Relationships of Hsp90

Volume:3   Issue: 5
Pp: 301-323
Chrisostomos Prodromou and Laurence H. Pearl
DOI: 10.2174/1568009033481877

Natural Product Origins of Hsp90 Inhibitors

Volume:3   Issue: 5
Pp: 325-330
Yoshimasa Uehara
DOI: 10.2174/1568009033481796

Genes and Proteins Governing the Cellular Sensitivity to HSP90 Inhibitors: A Mechanistic Perspective

Volume:3   Issue: 5
Pp: 331-341
Alison Maloney, Paul A. Clarke and Paul Workman
DOI: 10.2174/1568009033481822

The Stress Response: Implications for the Clinical Development of Hsp90 Inhibitors

Volume:3   Issue: 5
Pp: 349-358
Luke Whitesell, Rochelle Bagatell and Ryan Falsey
DOI: 10.2174/1568009033481787

Development of Radicicol Analogues

Volume:3   Issue: 5
Pp: 359-369
Shiro Soga, Yukimasa Shiotsu, Shiro Akinaga and Sreenath V. Sharma
DOI: 10.2174/1568009033481859

Development of Purine-Scaffold Small Molecule Inhibitors of Hsp90

Volume:3   Issue: 5
Pp: 371-376
Gabriela Chiosis, Brian Lucas, Henri Huezo, David Solit, Andrea Basso and Neal Rosen
DOI: 10.2174/1568009033481778

Clinical Development of 17-Allylamino, 17-Demethoxygeldanamycin

Volume:3   Issue: 5
Pp: 377-383
Edward A. Sausville, Joseph E. Tomaszewski and Percy Ivy
DOI: 10.2174/1568009033481831

The Clinical Applications of Heat Shock Protein Inhibitors in Cancer - Present and Future

Volume:3   Issue: 5
Pp: 385-390
Udai Banerji, Ian Judson and Paul Workman
DOI: 10.2174/1568009033481813