Current Cancer Drug Targets

Ruiwen Zhang 
Texas Tech University Health Sciences Center
1300 Coulter Drive
Amarillo, TX 79106
USA

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Editor's Choice

Coinhibitory Molecule PD-1 as a Therapeutic Target in the Microenvironment of Multiple Myeloma

Volume: 17   Issue: 9
Pp: 839-845
Djordje Atanackovic, Tim Luetkens, Sabari Radhakrishnan and Nicolaus Kroger*
DOI: 10.2174/1568009617666170906170348

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Potential Therapeutic Targets in Energy Metabolism Pathways of Breast Cancer

Volume: 17   Issue: 8
Pp: 707-721
Rowshan Ara Islam, Sazzad Hossain and Ezharul Hoque Chowdhury*
DOI: 10.2174/1568009617666170330150458

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Epstein-Barr Virus-associated Gastric Cancer and Potential Mechanisms of Oncogenesis

Volume: 17   Issue: 6
Pp: 534-554
Abigail Morales-Sanchez and Ezequiel M. Fuentes-Panana*
DOI: 10.2174/1568009616666160926124923

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Identification of Novel Agents for the Treatment of Brain Metastases of Breast Cancer

Volume: 17   Issue: 5
Pp: 479-485
Vinay K. Venishetty, Werner J. Geldenhuys, Tori B. Terell-Hall, Jessica I.G. Griffith, Gregory R. Sondag, Fayez F. Safadi and Paul R. Lockman*
DOI: 10.2174/1568009617666161121123948

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Hitting a Moving Target: Glioma Stem Cells Demand New Approaches in Glioblastoma Therapy

Volume: 17   Issue: 3
Pp: 236-254
Drew A. Spencer, Brenda M. Auffinger, Jason P. Murphy, Megan E. Muroski, Jian Qiao, Yureve Gorind and Maciej S. Lesniak
DOI: 10.2174/1568009616666161215161924

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Does Hypoxic Response Mediate Primary Resistance to Sunitinib in Untreated Locally Advanced Breast Cancer?

Volume: 17   Issue: 1
Pp: 62-73
Sofia Braga, Joana Cardoso, Saudade Andre, Margarida Brito, Pedro Sanchez, Lurdes Orvalho, Lucilia Salgado, Sergio Dias, Jose B. Pereira-Leal and Jose Luis Passos-Coelho
DOI: 10.2174/1568009616666161025114914

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Pyrimethamine as a Potent and Selective Inhibitor of Acute Myeloid Leukemia Identified by High-throughput Drug Screening

Volume: 16   Issue: 9
Pp: 818-828
Amit Sharma, Nidhi Jyotsana, Courteney K. Lai, Anuhar Chaturvedi, Razif Gabdoulline, Kerstin Görlich, Cecilia Murphy, Jan E. Blanchard, Arnold Ganser, Eric Brown, John A. Hassell, R. Keith Humphries, Michael Morgan and Michael Heuser
DOI: 10.2174/1568009616666160617103301

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Deregulation of Apoptosis - Is it Still an Important Issue in Pathogenesis of Chronic Lymphocytic Leukemia?

Volume: 16   Issue: 8
Pp: 652-658
Monika Podhorecka, Arkadiusz Macheta, Maria Bozko, Andrzej Bozko, Nisar P. Malek and Przemyslaw Bozko
DOI: 10.2174/1568009616666160427103930

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MT1-MMP Activation of TGF-β Signaling Enables Intercellular Activation of an Epithelial-mesenchymal Transition Program in Cancer

Volume: 16   Issue: 7
Pp: 618-630
Hoang-Lan Nguyen, Pournima Kadam, Alex Helkin, Kevin Cao, Song Wu, Ghassan J. Samara, Qian Zhang, Stanley Zucker and Jian Cao
DOI: 10.2174/1568009616666160216125634

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Recent Advances in Site Specific Conjugations of Antibody Drug Conjugates (ADCs)

Volume: 16   Issue: 6
Pp: 469-479
Wenlong Gao, Jingxin Zhang, Jun Xiang, Lei Zhang, Chengbin Wu, Pradeep K. Dhal and Bo Chen
DOI: 10.2174/1568009616666160512144715

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Targeting ABCB1 and ABCC1 with their Specific Inhibitor CBT-1® can Overcome Drug Resistance in Osteosarcoma

Volume: 16   Issue: 3
Pp: 261-274
Marilù Fanelli, Claudia Maria Hattinger, Serena Vella, Elisa Tavanti, Francesca Michelacci, Beth Gudeman, Daryl Barnett, Piero Picci and Massimo Serra
DOI: 10.2174/1568009616666151106120434

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Molecular Genetics and Targeted Therapy in Hepatocellular Carcinoma promotion: free to download

Volume: 16   Issue: 1
Pp: 53-70
Eric I. Marks and Nelson S. Yee
DOI: 10.2174/1568009615666150916092903

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Nanobiotechnological Approaches to Overcome Drug Resistance in Breast Cancer

Volume: 15   Issue: 7
Pp: 544-562
Peyman Ranji, Zahra Heydari and Ali Mohammad Alizadeh
DOI: 10.2174/1568009615666150706102842

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Target Acquired: Progress and Promise of Targeted Therapeutics in the Treatment of Prostate Cancer

Volume: 15   Issue: 5
Pp: 394-405
Ryan Stuchbery, Natalie J. Kurganovs, Patrick J. McCoy, Colleen C. Nelson, Vanessa M. Hayes, Niall M. Corcoran and Christopher M. Hovens
DOI: 10.2174/1568009615666150416113453

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A Pan-Cancer Review of ALK Mutations: Implications for Carcinogenesis and Therapy

Volume: 15   Issue: 4
Pp: 327-336
Nick Ka Ming Yau, Andrew Yuon Fong, Hiu Fung Leung, Krista Roberta Verhoeft, Qin Ying Lim, Wai Yip Lam, Ian Chi Kei Wong and Vivian Wai Yan Lui
DOI: 10.2174/1568009615666150225123712

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Present, Emerging and Possible Future Biomarkers in Castration Resistant Prostate Cancer (CRPC)

Volume: 15   Issue: 3
Pp: 243-255
Martin Boegemann, Andres-Jan Schrader, Laura-Maria Krabbe and Edwin Herrmann
DOI: 10.2174/1568009615666150204145803

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Involvement of Mesenchymal Stem Cells in Cancer Progression and Metastases

Volume: 15   Issue: 2
Pp: 88-98
Astra I. Chang, Aaron H. Schwertschkow, Jan A. Nolta and Jian Wu
DOI: 10.2174/1568009615666150126154151

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Potential Anti-cancer Drugs Commonly Used for Other Indications promotion: free to download

Volume: 15   Issue: 1
Pp: 35-52
Veronika Hanusova, Lenka Skalova, Vera Kralova and Petra Matouskova
DOI: 10.2174/1568009615666141229152812

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Looking out for Cancer Stem Cells’ Properties: The Value-Driving Role of CD44 for Personalized Medicines

Volume: 14   Issue: 9
Pp: 832-849
Sara Horta, Ana L. Agostinho, Rita Mateus, Lucilia Pereira, Carolina Pereira, Liliana Capinha, Slavomira Doktorovova, Alexandra Brito and Mafalda Videira
DOI: 10.2174/1568009614666141111154713

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Heat Shock Proteins as Prognostic Markers of Cancer

Volume: 14   Issue: 8
Pp: 713-726
Evgeniya V. Kaigorodova and Mariya V. Bogatyuk
DOI: 10.2174/1568009614666140926122846

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The Activation of β1-integrin by Type I Collagen Coupling with the Hedgehog Pathway Promotes the Epithelial-Mesenchymal Transition in Pancreatic Cancer

Volume: 14   Issue: 5
Pp: 446-457
Wanxing Duan, Jiguang Ma, Qingyong Ma, Qinhong Xu, Jianjun Lei, Liang Han, Xuqi Li, Zheng Wang, Zheng Wu, Shifang Lv, Zhenhua Ma, Mouzhu Liu, Fengfei Wang and Erxi Wu
DOI: 10.2174/1568009614666140402105101

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Metabolic Features of Melanoma: A Gold Mine of New Therapeutic Targets?

Volume: 14   Issue: 4
Pp: 357-370
Philippe Marchetti, Pierre Guerreschi, Jerome Kluza and Laurent Mortier
DOI: 10.2174/1568009614666140407113124

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Targeting BMP9-Promoted Human Osteosarcoma Growth by Inactivation of Notch Signaling

Volume: 14   Issue: 3
Pp: 274-285
Ruidong Li, Wenwen Zhang, Jing Cui, Wei Shui, Liangjun Yin, Yang Wang, Hongyu Zhang, Ning Wang, Ningning Wu, Guoxin Nan, Xian Chen, Sheng Wen, Fang Deng, Hongmei Zhang, Guolin Zhou, Zhan Liao, Junhui Zhang, Qian Zhang, Zhengjian Yan, Wei Liu, Zhonglin Zhang, Jixing Ye, Youlin Deng, Hue H. Luu, Rex C. Haydon, Tong-Chuan He and Zhong-Liang Deng
DOI: 10.2174/1568009614666140305105805

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