Current Cancer Drug Targets


Ruiwen Zhang
Center for Drug Discovery
University of Houston
3455 Cullen Blvd.
Houston, TX 77204


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Most Cited Article

Clinical Trials with Oncolytic Measles Virus: Current Status and Future Prospects

Volume:18   Issue:2
Pp: 177-187
Pavlos Msaouel, Mateusz Opyrchal, Angela Dispenzieri, Kah Whye Peng, Mark J. Federspiel, Stephen J. Russell and Evanthia Galanis*
DOI: 10.2174/1568009617666170222125035

MicroRNA Key to Angiogenesis Regulation: MiRNA Biology and Therapy

Volume:18   Issue:3
Pp: 266-277
Ankit Tiwari, Bratati Mukherjee and Manjusha Dixit*
DOI: 10.2174/1568009617666170630142725

Oxidative Stress and Cancer: The Role of Nrf2

Volume:18   Issue:6
Pp: 538-557
Soraya Sajadimajd and Mozafar Khazaei*
DOI: 10.2174/1568009617666171002144228

TGF-β1 Causes EMT by Regulating N-Acetyl Glucosaminyl Transferases via Downregulation of Non Muscle Myosin II-A through JNK/P38/PI3K Pathway in Lung Cancer

Volume:18   Issue:2
Pp: 209-219
Ghulam Jilany Khan, Yingsheng Gao, Ming Gu, Lai Wang, Sara Khan, Farah Naeem, Herve Semukunzi, Debmalya Roy, Shengtao Yuan* and Li Sun*
DOI: 10.2174/1568009617666170807120304

Metastatic Colorectal Cancer: Role of Target Therapies and Future Perspectives

Volume:18   Issue:5
Pp: 421-429
Anna Nappi, Massimiliano Berretta, Carmela Romano, Salvatore Tafuto, Antonino Cassata, Rossana Casaretti, Lucrezia Silvestro, Chiara De Divitiis, Lara Alessandrini, Francesco Fiorica, Alessandro Ottaiano and Guglielmo Nasti*
DOI: 10.2174/1568009617666170209095143

Polyploid Giant Cancer Cells (PGCCs): The Evil Roots of Cancer

Volume:19   Issue:5
Pp: 360-367
Junsong Chen, Na Niu, Jing Zhang, Lisha Qi, Weiwei Shen, Krishna Vanaja Donkena, Zhenqing Feng and Jinsong Liu*
DOI: 10.2174/1568009618666180703154233

Antibody Based EpCAM Targeted Therapy of Cancer, Review and Update

Volume:18   Issue:9
Pp: 857-868
Shirin Eyvazi, Safar Farajnia*, Siavoush Dastmalchi, Farzad Kanipour, Habib Zarredar and Mojghan Bandehpour
DOI: 10.2174/1568009618666180102102311

Cell-derived Exosomes as Promising Carriers for Drug Delivery and Targeted Therapy

Volume:18   Issue:4
Pp: 347-354
Xinyi Wang, Haiyang Zhang, Haiou Yang, Ming Bai, Tao Ning, Shuang Li, Jialu Li, Ting Deng, Guoguang Ying* and Yi Ba*
DOI: 10.2174/1568009617666170710120311

Synthetic Lethality: From Research to Precision Cancer Nanomedicine

Volume:18   Issue:4
Pp: 337-346
Anuradha Gupta, Anas Ahmad, Aqib Iqbal Dar and Rehan Khan*
DOI: 10.2174/1568009617666170630141931

Multimodal HDAC Inhibitors with Improved Anticancer Activity

Volume:18   Issue:1
Pp: 39-56
Rainer Schobert and Bernhard Biersack*
DOI: 10.2174/1568009617666170206102613

Ponatinib: A Review of Efficacy and Safety

Volume:18   Issue:9
Pp: 847-856
Fulvio Massaro, Matteo Molica and Massimo Breccia*
DOI: 10.2174/1568009617666171002142659

Current and Emerging Treatments for Metastatic Renal Cell Carcinoma

Volume:18   Issue:5
Pp: 468-479
Carla Cavaliere, Carmine D`Aniello, Chiara Della Pepa, Salvatore Pisconti, Massimiliano Berretta and Gaetano Facchini*
DOI: 10.2174/1568009617666170209094030

Epigenetic Regulation of EMT in Non-Small Cell Lung Cancer

Volume:18   Issue:1
Pp: 89-96
Karen O’Leary, Alice Shia and Peter Schmid*
DOI: 10.2174/1568009617666170203162556

Epigenetics in Metastatic Breast Cancer: Its Regulation and Implications in Diagnosis, Prognosis and Therapeutics

Volume:19   Issue:2
Pp: 82-100
Yuan Seng Wu, Zhong Yang Lee, Lay-Hong Chuah, Chun Wai Mai and Siew Ching Ngai*
DOI: 10.2174/1568009618666180430130248

Parp Inhibitors for the Treatment of Ovarian Cancer

Volume:18   Issue:9
Pp: 877-893
Laura Cortesi, Angela Toss* and Iole Cucinotto
DOI: 10.2174/1568009618666180308104646

Metastatic Site Location Influences the Diagnostic Accuracy of ctDNA EGFR- Mutation Testing in NSCLC Patients: a Pooled Analysis

Volume:18   Issue:7
Pp: 697-705
Francesco Passiglia, Sergio Rizzo, Christian Rolfo, Antonio Galvano, Enrico Bronte, Lorena Incorvaia, Angela Listi, Nadia Barraco, Marta Castiglia, Valentina Calo, Viviana Bazan and Antonio Russo*
DOI: 10.2174/1568009618666180308125110

Involvement of CD24 in Multiple Cancer Related Pathways Makes It an Interesting New Target for Cancer Therapy

Volume:18   Issue:4
Pp: 328-336
Shirin Eyvazi, Bahram Kazemi, Siavoush Dastmalchi* and Mojgan Bandehpour*
DOI: 10.2174/1570163814666170818125036

Targeting FGFR with BGJ398 in Breast Cancer: Effect on Tumor Growth and Metastasis

Volume:18   Issue:10
Pp: 979-987
Ana Sahores, María May, Gonzalo R. Sequeira, Cynthia Fuentes, Britta Jacobsen, Claudia Lanari and Caroline A. Lamb*
DOI: 10.2174/1568009618666171214114706

p53-Mdm2 Interaction Inhibitors as Novel Nongenotoxic Anticancer Agents

Volume:18   Issue:8
Pp: 749-772
Surendra Kumar Nayak*, Gopal L. Khatik, Rakesh Narang, Vikramdeep Monga and Harish Kumar Chopra
DOI: 10.2174/1568009617666170623111953