Anti-Cancer Agents in Medicinal Chemistry

(Formerly Current Medicinal Chemistry - Anti-Cancer Agents)

Michelle Prudhomme  
Universite Blaise Pascal - C.N.R.S
Aubiere Cedex
France

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Open Access Articles

Regulation of Apoptosis by SYB in HepG2 Liver Cancer Cells is Mediated by the P53/Caspase 9 Axis open Access plus

Volume: 17   Issue: 7
Pp: 941-947
Sharula and Zhongjun Wu
DOI:10.2174/1871520617666170327161433

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Epigenetic and miRNAs Dysregulation in Prostate Cancer: The role of Nutraceuticals open Access plus

Volume: 16   Issue: 11
Pp: 1385-1402
Alessandra Bosutti, Fabrizio Zanconati, Gabriele Grassi, Barbara Dapas, Sabina Passamonti and Bruna Scaggiante
DOI:10.2174/1871520616666160425105257

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Blood-Brain Barrier and Breast Cancer Resistance Protein: A Limit to the Therapy of CNS Tumors and Neurodegenerative Diseases open Access plus

Volume: 16   Issue: 7
Pp: 810-815
Anna Lisa Iorio, Martina da Ros, Ornella Fantappiè, Maurizio Lucchesi, Ludovica Facchini, Alessia Stival, Sabrina Becciani, Milena Guidi, Claudio Favre, Maurizio de Martino, Lorenzo Genitori and Iacopo Sardi
DOI:10.2174/1871520616666151120121928

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The Use of Anthracyclines for Therapy of CNS Tumors open Access plus

Volume: 15   Issue: 6
Pp: 721-727
Martina da Ros, Anna Lisa Iorio, Maurizio Lucchesi, Alessia Stival, Maurizio de Martino and Iacopo Sardi
DOI:10.2174/1871520615666150407155319

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Using Cytochalasins to Improve Current Chemotherapeutic Approaches open Access plus

Volume: 15   Issue: 3
Pp: 327-335
Matthew Trendowski
DOI:10.2174/1871520614666141016164335

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Synthesis, Preferentially Hypoxic Apoptosis and Anti-Angiogenic Activity of 3- Amino-1,2,4-Benzotriazine-1,4-Dioxide Bearing Alkyl Linkers with a 3-Amino-1,2,4- Benzotriazine-1-Oxide Moiety open Access plus

Volume: 14   Issue: 10
Pp: 1428-1446
Chun-I Lee, Chien-Ming Huang, Wen-Hsin Huang and An-Rong Lee
DOI:10.2174/1871520614666141014130554

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Episensitization: Therapeutic Tumor Resensitization by Epigenetic Agents: A Review and Reassessment open Access plus

Volume: 14   Issue: 8
Pp: 1121-1127
Bryan Oronsky, Neil Oronsky, Susan Knox, Gary Fanger and Jan Scicinski
DOI:10.2174/1871520614666140418144610

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Preclinical Development of Novel Rac1-GEF Signaling Inhibitors using a Rational Design Approach in Highly Aggressive Breast Cancer Cell Lines open Access plus

Volume: 14   Issue: 6
Pp: 840-851
Georgina A. Cardama, Maria J. Comin, Leandro Hornos, Nazareno Gonzalez, Lucas Defelipe, Adrian G. Turjanski, Daniel F. Alonso, Daniel E. Gomez and Pablo Lorenzano Menna
DOI:10.2174/18715206113136660334

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β2-Microglobulin-mediated Signaling as a Target for Cancer Therapy open Access plus

Volume: 14   Issue: 3
Pp: 343-352
Takeo Nomura, Wen-Chin Huang, Haiyen E. Zhau, Sajni Josson, Hiromitsu Mimata and Leland W. K. Chung
DOI:10.2174/18715206113139990092

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The Immunomodulation and Anti-Inflammatory Effects of Garlic Organosulfur Compounds in Cancer Chemoprevention open Access plus

Volume: 14   Issue: 2
Pp: 233-240
Georgia Schäfer and Catherine H. Kaschula
DOI:10.2174/18715206113136660370

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Cytotoxicity and Apoptosis Induced by a Plumbagin Derivative in Estrogen Positive MCF-7 Breast Cancer Cells open Access plus

Volume: 14   Issue: 1
Pp: 170-180
Sunil Sagar, Luke Esau, Basem Moosa, Niveen M. Khashab, Vladimir B. Bajic and Mandeep Kaur
DOI:10.2174/18715206113136660369

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Differential Effects of Polyphenols on Proliferation and Apoptosis in Human Myeloid and Lymphoid Leukemia Cell Lines open Access plus

Volume: 13   Issue: 10
Pp: 1601-1613
Amani A Mahbub, Christine L. Le Maitre, Sarah L. Haywood-Small, Gordon J. McDougall, Neil A. Cross and Nicola Jordan-Mahy
DOI:10.2174/18715206113139990303

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The Use of Lentinan for Treating Gastric Cancer open Access plus

Volume: 13   Issue: 5
Pp: 681-688
Kenji Ina, Takae Kataoka and Takafumi Ando
DOI:10.2174/1871520611313050002

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Redox-inactive Analogue of Tocotrienol as a Potential Anti-cancer Agent open Access plus

Volume: 13   Issue: 3
Pp: 496-501
Tomohiro Yano, Ayami Sato, Miki Sekine, Nantiga Virgona and Masako Ota
DOI:10.2174/1871520611313030012

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Are KRAS/BRAF Mutations Potent Prognostic and/or Predictive Biomarkers in Colorectal Cancers? open Access plus

Volume: 12   Issue: 2
Pp: 163-171
Tomoya Yokota
DOI:10.2174/187152012799014968

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Cilengitide: The First Anti-Angiogenic Small Molecule Drug Candidate. Design, Synthesis and Clinical Evaluation open Access plus

Volume: 10   Issue: 10
Pp: 753-768
Carlos Mas-Moruno, Florian Rechenmacher and Horst Kessler
DOI:10.2174/187152010794728639

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Pharmacogenomics of Human ABC Transporter ABCC11 (MRP8): Potential Risk of Breast Cancer and Chemotherapy Failure open Access plus

Volume: 10   Issue: 8
Pp: 617-624
Yu Toyoda and Toshihisa Ishikawa
DOI:10.2174/187152010794473975

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New Medical Strategies for Midgut Carcinoids open Access plus

Volume: 10   Issue: 3
Pp: 250-269
Ola Nilsson, Yvonne Arvidsson, Viktor Johanson, Eva Forssell-Aronsson and Hakan Ahlman
DOI:10.2174/1871520611009030250

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Targeting RSK: An Overview of Small Molecule Inhibitors open Access plus

Volume: 8   Issue: 7
Pp: 710-716
Tam Luong Nguyen
DOI:10.2174/187152008785914770

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Regulation of the Endoplasmic Reticulum Ca2+-Store in Cancer open Access plus

Volume: 8   Issue: 7
Pp: 705-709
A. Bergner and R. M. Huber
DOI:10.2174/187152008785914734

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The Protein Kinase Inhibitor Balanol: Structure – Activity Relationships and Structure-Based Computational Studies open Access plus

Volume: 8   Issue: 6
Pp: 638-645
Vineet Pande, Maria J. Ramos and Federico Gago
DOI:10.2174/187152008785133056

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Role of Mismatch Repair and MGMT in Response to Anticancer Therapies open Access plus

Volume: 8   Issue: 4
Pp: 368-380
Ida Casorelli, Maria Teresa Russo and Margherita Bignami
DOI:10.2174/187152008784220276

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Inhibition of Protein Kinase c-Src as a Therapeutic Approach for Cancer and Bone Metastases open Access plus

Volume: 8   Issue: 3
Pp: 342-349
Nadia Rucci, Maria Susa and Anna Teti
DOI:10.2174/187152008783961905

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