Anti-Cancer Agents in Medicinal Chemistry

(Formerly Current Medicinal Chemistry - Anti-Cancer Agents)

This journal supports open access

Editor-in-Chief:

Michelle Prudhomme
Institut de Chimie de Clermont-Ferrand
ICCF-CNRS UMR 6296
Université Clermont Auvergne
Clermont-Ferrand
France

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Articles Ahead of Print

Activation of PI3K/Akt/NF-kB Signaling Mediates Swedish Snus Induced Proliferation and Apoptosis Evasion in the Rat Forestomach: Modulation by Blueberry

Volume:19
Singaraj Ranjani, Jaganathan Kowshik, Josephraj Sophia, Ramesh Nivetha, Abdul B. Baba, Veeran Veeravarmal, Gordana Joksić, Lars E. Rutqvist, Robert Nilsson and Siddavaram Nagini*

Design, Synthesis and Evaluation of Novel Substituted (5-methyl-1H-pyrazol-3-yl)- 1,3,4-oxadiazole as Potent Androgen Receptor Antagonist

Volume:19
Sasikumar Andavar*, Mohanasrinivasan Vaithilingam*, Divakar Selvaraj, Ajeeshkumar A. Kumaran and Krishnaswamy Devanathan

New Entrants into Clinical Trials for Targeted Therapy of Breast Cancer: An Insight

Volume:19
Priyanka Verma, Pooja Mittal, Archana Singh* and Indrakant K. Singh*

Furanocoumarin A, A Novel Anticancer Agent on Human Lung Cancer A549 Cells, from Fructus Liquidambaris

Volume:19
Hui Fang and Hongmei Ji*

Oxidative Stress Modulation and Radiosensitizing Effect of Quinoxaline-1,4-Dioxides Derivatives

Volume:19
Liliana Silva, Pedro Coelho, Dulce Teixeira, Armanda Monteiro, Gabriela Pinto, Raquel Soares, Cristina Prudêncio and Mónica Vieira*

High Expression of SIRT1 Associates with the Doxorubicin Resistance of Breast Cancer through the Activation of Akt

Volume:19
Xiaoxia Jin, Yingze Wei, Yushan Liu, Yali Chen, Bin Zhao, Jieyu Huang, Haiyan Yu and Chunsun Li*

Anti-Tumour Activity of Glycodendrimer Nanoparticles in a Subcutaneous MEC-1 Xenograft Model of Human Chronic Lymphocytic Leukemia

Volume:19
Barbara Ziemba, Hanna Sikorska, Magdalena Jander, Wojciech Kuncman, Marian Danilewicz, Dietmar Appelhans, Maria Bryszewska, Maciej Borowiec and Ida Franiak-Pietryga*

Synthesis, Anticancer, and Antibacterial Activity of Betulinic and Betulonic Acid C-28-Triphenylphosphonium Conjugates with Variable Alkyl Linker Length

Volume:19
Olga V. Tsepaeva, Andrey V. Nemtarev*, Leysan R. Grigor`eva, Taliya I. Salikhova, Svetlana A. Khozyainova, Timur I. Abdullin and Vladimir F. Mironov

Zoning in on Tankyrases: A Brief Review on the Past, Present and Prospective Studies

Volume:19
Xylia Q. Peters, Thembeka H. Malinga, Clement Agoni, Fisayo A. Olotu and Mahmoud E.S. Soliman*

Highly Concentrated Multifunctional Silver Nanoparticle Fabrication through Green Reduction of Silver Ions in Terms of Mechanics and Therapeutic Potentials

Volume:19
Mohammad A. Ebrahimzadeh, Pourya Biparva, Hamidreza Mohammadi, Shirin Tavakoli, Alireza Rafiei, Mostafa Kardan, Hamid Badali and Shahram Eslami*

In Vitro Anticancer Activity of Virgin Coconut Oil and its Fractions in Liver and Oral Cancer Cells

Volume:19
Poonam Verma, Sanjukta Naik, Pranati Nanda, Silvi Banerjee, Satyanarayan Naik and Amit Ghosh*

Recent Advances in Characterizing Natural Products that Regulate Autophagy

Volume:19
Qian Zhao, Cheng Peng, Chuan Zheng, Xiang -Hong He, Wei Huang* and Bo Han*

Effect of Hsp90 Inhibitor KW-2478 on HepG2 Cells

Volume:19
Xiaomin Chang, Xuerong Zhao, Jianping Wang, Shi Ding, Lijun Xiao*, Enhong Zhao and Xin Zheng

Breast Cancer Targeted Treatment Strategies: Promising Nanocarrier Approaches

Volume:19
Ponnurengam M. Sivakumar, Palanivel Kandasamy, Siva Chidambaram, Devanand Venkatasubbu, Sathish K. Perumal and Sugumaran Abimanyu*

Signal Pathways and Therapeutic Prospects of Diffuse Large B Cell Lymphoma

Volume:19
Feifei Sun, Xiaosheng Fang* and Xin Wang*

Sera/Organ Lysates of Selected Animals Living in Polluted Environments Exhibit Cytotoxicity Against Cancer Cell Lines

Volume:19
Shareni Jeyamogan, Naveed A. Khan, Sagathevan K.* and Ruqaiyyah Siddiqui

Evaluation of Tissue and Serum Expression Levels of Lactate Dehydrogenase Isoenzymes in Patients with Head and Neck Squamous Cell Carcinoma

Volume:19
Nooshin Mohtasham, Hossein Ayatollahi, Nasrollah Saghravanian, Reza Zare, Mohammad-Taghi Shakeri, Amirhossein Sahebkar* and Farnaz Mohajertehran*

The Anti-tumor Activity and Mechanisms of rLj-RGD3 on Human Laryngeal Squamous Carcinoma Hep2 Cells

Volume:19
Yang Jin, Li Lv, Shu-Xiang Ning, Ji-Hong Wang* and Rong Xiao*

CRISPR/Cas9 System and its Research Progress in Gene Therapy

Volume:19
Wenlou Liu*, Chunsheng Yang*, Yanqun Liu and Guan Jiang

Synthesis of Substituted Cinnamido Linked Quinazolinone Congeners as Potential Anticancer Agents via Mitochondrial Dependent Intrinsic Apoptotic Pathway

Volume:19
Kesari Lakshmi Manasa, Mohd Aslam Saifi, Yellaiah Tangella, Chandraiah Godugu and Mallika Alvala*

Cyclodextrin-Based Nanosystems as Drug Carriers for Cancer Therapy

Volume:19
Ponnurengam Malliappan Sivakumar, Shohreh Peimanfard, Ali Zarrabi*, Arezoo Khosravi and Matin Islami

Cancer Nanotheranostics: A Nanomedicinal Approach for Cancer Therapy and Diagnosis

Volume:19
Paromita Kundu, Deepika Singh, Abhalaxmi Singh and Sanjeeb K Sahoo*

In Vitro Antitumor Evaluation of Some Hybrid Molecules Containing Coumarin and Quinolinone Moieties

Volume:19
Youstina W. Rizzk*, Ibrahim M. El-Deen, Faten Z. Mohammed, Moustafa S. Abdelhamid and Amgad I.M. Khedr

Effects of Somatostatin and Vitamin C on the Fatty Acid Profile of Breast Cancer Cell Membranes

Volume:19
Aysegul Hanikoglu, Ertan Kucuksayan, Ferhat Hanikoglu, Tomris Ozben*, Georgia Menounou, Anna Sansone, Chrys Chatgilialoglu, Giuseppe Di Bella and Carla Ferreri

Synergistic Effect of Α-Solanine and Cisplatin Induces Apoptosis and Enhances Cell Cycle Arrest in Human Hepatocellular Carcinoma Cells

Volume:19
Sherien M. El-Daly*, Shaimaa A. Gouhar, Amira M. Gamal-Eldeen, Fatma F. Abdel Hamid, Magdi N. Ashour and Nahla S. Hassan

Synthesis, In Vitro Evaluation, Molecular Docking and DFT Studies of Some Phenyl Isothiocyanates as Anticancer Agents

Volume:19
Kikoleho Richa, Rituparna Karmaker, Naruti Longkumer, Vishal Das, Pulak J. Bhuyan, Mintu Pal* and Upasana B. Sinha*

STAT5 and STAT5 Inhibitors in Hematological Malignancies

Volume:19
Manlio Tolomeo*, Maria Meli and Stefania Grimaudo

Kaempferol Improves TRAIL-Mediated Apoptosis in Leukemia MOLT-4 Cells by the Inhibition of Anti-Apoptotic Proteins and Promotion of Death Receptors Expression

Volume:19
Ali Hassanzadeh, Adel Naimi, Majid Farshousti Hagh, Raedeh Saraei, Faroogh Marofi and Saeed Solali*

The Effect of a Ferrocene Containing Camphor Sulfonamide DK-164 on Breast Cancer Cell Lines

Volume:19
Maria Schröder, Shazie Yusein-Myashkova, Maria Petrova, Georgi Dobrikov, Mariana Kamenova-Nacheva, Jordana Todorova, Evdokia Pasheva and Iva Ugrinova

The Correlation between EGFR and Androgen Receptor Pathways: A Novel Potential Prognostic Marker in Gastric Cancer

Volume:19
Shahrzad S. Fard, Kioomars Saliminejad, Masoud Sotoudeh, Niloofar Soleimanifard, Shaghayegh Kouchaki, Mansour Yazdanbod, Habibollah Mahmoodzadeh, Ardeshir Ghavamzadeh, Reza Malekzadeh, Bahram Chahardouli, Kamran Alimoghaddam* and Seyed H. Ghaffari*

Inhibition of Cancer Stem-Like Phenotype by Curcumin and Deguelin in CAL-62 Anaplastic Thyroid Cancer Cells

Volume:19
Mehmet A. Kocdor*, Hakan Cengiz, Halil Ates and Hilal Kocdor

Berberine as Source of Antiproliferative Hybrid Compounds: In Vitro Antiproliferative Activity and Quantitative Structure-Activity Relationship

Volume:19
Mario Alberto Leyva-Peraltaa, Ramón Enrique Robles-Zepedab, Rodrigo Said Razo-Hernándezc, Laura Patricia Álvarez Berberd, Karen Ochoa Laraa, Eduardo Ruiz-Bustosb and Juan Carlos Gálvez-Ruízb*

STK33-Dependent Transcriptional Regulation of SFTA3 Induces Cisplatin- Resistance in Lung Adenocarcinoma

Volume:19
Kuilong Zhou, Runzhi Dong, Zhiheng Wang, Zhian Tang, Xuezhen Gao, Yaqing Du, Xiaoli Zhang, Xiangying Li and Qingfan Xie*

The Pharmacogenomics “Side-effect” of TP53/EGFR in Non-small Cell Lung Cancer Accompanied with Atorvastatin Therapy: A Functional Network Analysis

Volume:19
Lei Zhang, Yifang Huang, Xuedong Gan, Siying He, Xiaohuan Cheng, Na Yang, Siwei Li, Zuhua Li and Fang Zheng*

Pyrrolo[1,2-a]azepines Coupled with Benzothiazole and Fluorinated Aryl Thiourea Scaffolds as Promising Antioxidant and Anticancer Agents

Volume:19
Rahul V. Patel*, Bhupendra M. Mistry, Riyaz Syed, Nikhil M. Parekh and Han-Seung Shin

Synthesis and Anticancer Activity of Benzimidazole/Benzoxazole Substituted Triazolotriazines in Hepatocellular Carcinoma

Volume:19
Sakineh Dadashpour, Tuba T. Küçükkılınç, Ayse Ercan, Seyed J. Hosseinimehr, Nima Naderi and Hamid Irannejad*

Jab1-siRNA Induces Cell Growth Inhibition and Cell Cycle Arrest in Gall Bladder Cancer Cells via Targeting Jab1 Signalosome

Volume:19
Pratibha Pandey, Mohammad H. Siddiqui, Anu Behari, V.K. Kapoor, Kumudesh Mishra, Uzma Sayyed, Rohit K. Tiwari, Rafia Shekh and Preeti Bajpai*

Lemon Juice Mediated Synthesis of 3-Substituted Quinazolin-4(3H)-Ones and their Pharmacological Evaluation

Volume:19
Malavattu G. Prasad, C. Vijaya Lakshmi, Naresh K. Katari*, Rajshekhar Karpoormath and Manojit Pal

An Approach to Treatment of Liver Cancer by Novel Glycyrrhizin Derivative

Volume:19
Fardous F. El-Senduny, Mahmoud M. Zidane, Magdy Mahfouz Youssef and Farid A. Badria*

Zinc Finger Nuclease Combines with Cisplatin and Trichostatin A Enhances the Antitumor Potency in Cervical Cancer Cells

Volume:18
Ci Ren, Chun Gao, Xiaomin Li, Hui Shen, Liming Wang, Da Zhu, Peng Wu, Ding Ma, Hui Wang* and Wencheng Ding*

New Derivatives of Bacteriopurpurin with Thiolated Au (I) Complexes: Dual Darkand Light Activated Antitumor Potency

Volume:19
Mikhail A. Grin*, Sergei I. Tikhonov, Albina S. Petrova, Victor A. Pogorilyy, Аlexey N. Noev, Victor V. Tatarskiy, Dmitry B. Shpakovsky, Elena R. Milaeva, Elena V. Kalinina, Nikolai N. Chernov, Аlexander А. Shtil, Andrei F. Mironov, Andrei D. Kaprin and Elena V. Filonenko

Design, In Silico Modelling, and Functionality Theory of Novel Folate Receptor Targeted Rutin Encapsulated Folic Acid Conjugated Keratin Nanoparticles for Effective Cancer Treatment

Volume:19
Selvaraj Kunjiappan, Theivendren Panneerselvam*, Saravanan Govindaraj, Pavadai Parasuraman, Suraj Baskararaj, Murugesan Sankaranarayanan, Sankarganesh Arunachalam, Ewa Babkiewicz, Aarthi Jeyakumar and Muthulakshmi Lakshmanan

Hydroxytyrosol and Oleuropein Inhibit Migration and Invasion of MDA-MB-231 Triple-Negative Breast Cancer Cell via Induction of Autophagy

Volume:19
Hui-Yuan Lu*, Jian-Sheng Zhu, Zhan Zhang, Wei-Jian Shen, Shan Jiang, Yun-Feng Long, Bin Wu, Tao Ding, Fei Huan and Shou-Lin Wang

Recent Advances of Silver Nanoparticles in Cancer Diagnosis and Treatment

Volume:19
Tran Q. Huy*, Pham T.M. Huyen, Anh-Tuan Le and Matteo Tonezzer

Natural Compounds Targeting Cancer Stem Cells: A Promising Resource for Chemotherapy

Volume:19
Plabon K. Das, Tasnim Zahan, Md. Abdur Rakib, Jahan A. Khanam, Suja Pillai and Farhadul Islam*

The Opposite Effect of L-kynurenine and Ahr Inhibitor Ch223191 on Apoptotic Protein Expression in Pancreatic Carcinoma Cells (Panc-1)

Volume:19
Anna Leja-Szpak*, Marta Góralska, Paweł Link-Lenczowski, Urszula Czech, Katarzyna Nawrot-Porąbka, Joanna Bonior and Jolanta Jaworek

Influence of New Synthetic Xanthones on the Proliferation and Migration Potential of Cancer Cell Lines in vitro

Volume:19
Natalia Szkaradek*, Daniel Sypniewski, Dorota Żelaszczyk, Sabina Gałka, Paulina Borzdziłowska, Henryk Marona and Ilona Bednarek

Selective Photodynamic Effects on Breast Cancer Cells Provided by P123 Pluronic®- Based Nanoparticles Modulating Hypericin Delivery

Volume:18
Gabrielle Marconi Zago Ferreira Damke, Raquel Pantarotto Souza, Maiara Camotti Montanha, Edilson Damke, Renato Sonchini Gonçalves, Gabriel Batista Cesar, Elza Kimura, Wilker Caetano, Noboru Hioka and Marcia Edilaine Lopes Consolaro*

Growth Kinetics and Oncologic Outcomes for Small Renal Masses Managed with Active Surveillance: A Review of the Literature

Volume:17
Benjamin T Ristau*, Thomas W Fuller, Ricardo Rios, Cristina Ho and Jeffrey J Tomaszewski