Anti-Cancer Agents in Medicinal Chemistry

(Formerly Current Medicinal Chemistry - Anti-Cancer Agents)

This journal supports open access

Editor-in-Chief:

Michelle Prudhomme
Institut de Chimie de Clermont-Ferrand
ICCF-CNRS UMR 6296
Université Clermont Auvergne
Clermont-Ferrand
France

Back

Ahead of Print Article(s)

Inhibition of Migration and Invasion of Hepatocarcinoma HepG2 Cells by Dietary Saponins via Targeting HIF-1α

Volume:18
Cheng Luo*, Di Wu, Meiling Chen, Wenhua Miao, Changfeng Xue, Yanhui Sun, Dequn Liu, Chong Xie, Yaqin Wang, Christopher Frenz and Shanggui Deng

Oxaliplatin Regulates Chemotherapy Induced Peripheral Neuropathic Pain in the Dorsal Horn and Dorsal Root Ganglion via the Calcineurin/NFAT Pathway

Volume:18
Wan Huang*, Jingxiu Huang, Yu Jiang, Xuanwei Huang, Wei Xing, Yaoxuan He and Handong Ouyang

DTCM-glutarimide Delays Growth and Radiosensitizes Glioblastoma

Volume:18
Gabriela Molinari Roberto, Helder Henrique Paiva, Lucas Eduardo Botelho de Souza , Julia Alejandra Pezuk, Gabriela Maciel Vieira , Harley Francisco de Oliveira , Kazuo Umezawa , Luiz Gonzaga Tone and María Sol Brassesco *

Antitumor Effect of Pomolic Acid in Acute Myeloid Leukemia Cells Involves Cell Death, Decreased Cell Growth and Topoisomerases Inhibition

Volume:18
Michelle X.G. Pereira, Amanda S.O Hammes, Flavia C. Vasconcelos, Aline R. Pozzo, Thais Hancio Pereira, Ernesto R. Caffarena, Cerli R. Gattass and Raquel Ciuvalschi Maia*

2-Methoxy-6-Acetyl-7-Methyljuglone (MAM) Induces iNOS/NO-mediated DNA Damage Response through Activation of MAPKs Pathways

Volume:18
Yanan Niu, Renyikun Yuan, Hongwei Gao, Qi Kong, Jin-Jian Lu and Xiuping Chen*

How Does Plasma Activated Media Treatment Differ From Direct Cold Plasma Treatment?

Volume:18
Pankaj Attri*, Ji Hoon Park, Anser Ali and Eun Ha Choi

Natural Macromolecules with Protective and Antitumor Activity

Volume:18
Cioanca Oana*, Trifan Adriana, Cornelia Mircea, Scripcariu Dragos and Hancianu Monica

Apoptosis Caused by Triterpenes and Phytosterols and Antioxidant Activity of an Enriched Flavonoid Extract from Passiflora mucronata

Volume:18
Isabel Cristina Vieira da Silva, Goran Kaluderovic, Pollyana Felix de Oliveira, Denise Oliveira Guimaraes, Carla Holandino Quaresma, Andrea Porzel, Michelle Frazao Muzitano, Ludger A. Wessjohann and Ivana Correa Ramos Leal*

Guide for Selection of Relevant Cell Lines During the Evaluation of New Anti-Cancer Compounds

Volume:18
Angel J. Ruiz-Moreno, Patricia Torres-Barrera, Mireya Velazquez-Paniagua, Alexander Domling and Marco A. Velasco-Velazquez*

7-O-aminoalkyl-2,3-dehydrosilibinins: Synthesis and in vitro Anti-cancer Efficacy

Volume:18
Da-You Ma*, Li-Chao Zhang, Kun-Jian Peng, Jiang Zeng, Li-Jun Liu, Zhi-Yong Luo * and Su-You Liu*

Inhibitory Effect of Filipendula ulmaria on Mammary Carcinogenesis Induced by Local Administration of Methylnitrosourea to Target Organ in Rats

Volume:18
Vladimir G. Bespalov*, Valerij A. Alexandrov, Galina I. Vysochina, Vera A. Kostikova, Alexandr L. Semenov and Denis A. Baranenko

Caffeine Effect on HIFs/VEGF Pathway in Human Glioblastoma Cells Exposed to Hypoxia

Volume:18
Grazia Maugeri, Agata Grazia D`Amico, Daniela Maria Rasa, Salvatore Saccone, Concetta Federico, Gaetano Magro, Sebastiano Cavallaro and Velia D`Agata*

Novel Hybrid Compound 4-[(E)-2-phenylethenesulfonamido]-N-hydroxybutanamide with Antimetastatic and Cytotoxic Action: Synthesis and Anticancer Screening

Volume:18
Yurii L. Zborovskii, Viktor V. Orysyk, Iuliia Golovynska*, Olena I. Dzhus, Liudmyla V. Garmanchuk, Iurii V. Stepanov, Natalia Khranovska, Anatolii O. Nehelia, Sergii Golovynskyi, Tymish Y. Ohulchanskyy*, Junle Qu*, Svitlana I. Orysyk, Vasyl I. Pekhno and Myhaylo V. Vovk

68Ga-labeled HBED-CC Variant of uPAR Targeting Peptide AE105 Compared with 68Ga-NODAGA-AE105

Volume:18
Kusum Vats, Rohit Sharma, Haladhar Dev Sarma, Drishty Satpati* and Ashutosh Dash

Synthesis and Anticancer Properties of Novel Truncated Carbocyclic Nucleoside Analogues

Volume:18
Shantanu Pal*, Manas Kumar Santra, Maddi Saranya, Amarendra Panda, Sehbanul Islam and Balija Sivakrishna

Synthesis and Biological Evaluation of New 1,3,4-Oxadiazoles as Potential Anticancer Agents and Enzyme Inhibitors

Volume:18
Leyla Yurttas*, Betul Kaya, Gulsen Akalin Ciftci and Halide Edip Temel

Heterocyclic Compounds: 2-Pyrazolines are Biologically Active as well as Fluorescence Agents: An Overview

Volume:18
Pramod Singh Negi*, Jitendra Singh, Geeta Joshi nee Pant and MSM Rawat

Suppression of the Viability and Proliferation of HepG2 Hepatocellular Carcinoma Cell Line by Konjac Glucomannan

Volume:18
Sakunie Sawai, Mas Sahidayana Mokhtar, Wan Kamarul Zaman Wan Safwani* and Thamil Selvee Ramasamy

99mTc-(tricine)-HYNIC-Lys-FROP Peptide for Breast Tumor Targeting

Volume:18
Seyed Jalal Hosseinimehr*, Sajjad Ahmadpour, Zohraeh Noaparast and Seyed Mohamamd Abedi

Potential Pharmacological Inhibitors of Pim Kinase Under Clinical Trials

Volume:18
Gomathi Priya Jeyapal, MJN Chandrasekar*, Rajendiran Krishnasamy, Jubie Selvaraj, Manal Mohammad and MJ Nanjan

PLK1 Inhibition Radiosensitizes Breast Cancer Cells, but Shows Low Efficacy as Monotherapy or in Combination with other Cytotoxic Drugs

Volume:18
Maria Sol Brassesco*, Julia Alejandra Pezuk, Karina Bezerra Salomao, Gabriela Molinari Roberto, Carlos Alberto Scrideli and Luiz Gonzaga Tone

Sorafenib as a Salvage Therapy in FLT3-ITD Negative Relapse/Refractory Acute Myeloid Leukemia

Volume:18
Nan Yang, Zhenyang Gu, Zhanxiang Liu, Wenrong Huang, Shuhong Wang, Lili Wang and Chunji Gao*

Riluzole Inhibits Proliferation, Migration and Cell Cycle Progression and Induces Apoptosis in Tumor Cells of Various Origins

Volume:18
Marta Kinga Lemieszek*, Andrzej Stepulak, Katarzyna Sawa-Wejksza, Arkadiusz Czerwonka, Chrysanthy Ikonomidou and Wojciech Rzeski

AMPA Receptor Antagonist CFM-2 Decreases Survivin Expression in Cancer Cells

Volume:18
Domingo Sanchez*, Hella Luksch, Marco Sifringer, Achim Temme, Christian Staufner, Wojciech Rzeski, Aneta Grabarska, Chrysanthy Ikonomidou and Andrzej Stepulak

Synthesis and Biological Evaluation of Novel Triazoles Linked 7-hydroxycoumarin as Potent Cytotoxic Agents

Volume:18
Saleem Farooq*, Aashiq Hussain, Mushtaq A. Qurishi, Abid Hamid* and S Koul*

Synthesis and Evaluation of 2-Naphthaleno trans-Stilbenes and Cyanostilbenes as Anticancer Agents

Volume:17
Nikhil R. Madadi, Narsimha R. Penthala, Amit Ketkar, Robert L. Eoff, Vicenta Trujillo-Alonso, Monica L. Guzman and Peter A. Crooks*

Melatonin Differentially Modulates NF-кB Expression in Breast and Liver Cancer Cells

Volume:18
Jucimara Colombo, Bruna Victorasso Jardim-Perasssi, Joao Paulo Senna Ferreira, Cristine Zampieri Braga, Nathalia Martins Sonehara, Rubens de Paula Júnior, Marina Gobbe Moschetta, Ana Paula Girol and Debora Aparecida Pires de Campos Zuccari*

Anticancer Activity Study of Chromone and Coumarin Hybrids using Electrical Impedance Spectroscopy

Volume:18
Mustapha M. Bouhenna, Monica Vara Perez, Oualid Talhi, Khaldoun Bachari, Artur M. S. Silva, Walter Luyten and Nabil Mameri*

HPLC Analysis of Phenolic Acids, Antioxidant Activity and in vitro Effectiveness of Green and Roasted Caffea arabica Bean Extracts: A Comparative Study

Volume:18
Sobhy El-Sayed Hassab El-Nabi, Gouda T.M. Dawoud, Islam Mohamed El-Garawani and Samraa Samy El_Shafey*

Synthesis of Novel Thieno[2,3-d]pyrimidine Derivatives and Evaluation of Their Cytotoxicity and EGFR Inhibitory Activity

Volume:18
Farag A. El-Telbany, Ehab M. Gedawy*, Afaf A. El-Malah and Mina E. Adly

Edelfosine: An Antitumor Drug Prototype

Volume:18
Sarah Fernandes Teixeira, Cecilia Pessoa Rodrigues, Cicero Julio Silva Costa, Thais Narimatsu Pettinati, Ricardo Alexandre de Azevedo, Lisley Inata Mambelli, Salomao Doria Jorge, Rodrigo Nalio Ramos, Emer Suavinho Ferro, Jose Alexandre Marzagão Barbuto and Adilson Kleber Ferreira*

Growth Kinetics and Oncologic Outcomes for Small Renal Masses Managed with Active Surveillance: A Review of the Literature

Volume:17
Benjamin T Ristau*, Thomas W Fuller, Ricardo Rios, Cristina Ho and Jeffrey J Tomaszewski

Computational Study of the Binding Modes of Diverse DPN Analogues on Estrogen Receptors (ER) and the Biological Evaluation of a New Potential Antiestrogenic Ligand

Volume:18
M. Martinez-Archundia*, J B García-Vázquez, B Colin-Astudillo, M. Bello , B. Prestegui-Martel, A. Chavez-Blanco, A. Dueñas-González, M. J. Fragoso-Vázquez, J. Mendieta-Wejebe, E. Abarca-Rojano, D. Ordaz-Rosado, R. García-Becerra, D. Castillo-Bautista and J. Correa Basurto

Design, Synthesis, and Biological Evaluation of New Azole Derivatives as Potent Aromatase Inhibitors with Potential Effects against Breast Cancer

Volume:18
Fatemeh Kalalinia, Mohammad Jouya, Alireza Khorsand Komachal, Aboutourabzadeh Seyed Mohammad, Gholamreza Karimi, Javad Behravan, Khalil Abnous, Leila Etemad, Hossein Kamali and Farzin Hadizadeh*

Nanoemulsion Strategy for Ursolic and Oleanic Acids Isolates from Plumeria Obtusa Improves Antioxidant and Cytotoxic Activity in Melanoma Cells

Volume:18
Helen L Alvarado, Ana C Calpena, Maria L Garduno-Ramirez, Raul Ortiz, Consolacion Melguizo, Jose M. Prados and Beatriz Clares*

Design, Synthesis and Biological Evaluation of Novel Urea and Thiourea Bearing thieno[3,2-d]-pyrimidines as PI3 Kinase Inhibitors

Volume:18
Srinu Bodige, Parameshwar Ravula, Kali Charan Gulipalli, Srinivas Endoori, JN Narendra Sharath Chandra, Purna Koteswara Rao Cherukumalli, G R Vanaja and Naresh Varma Seelam*

Synthesis and Evaluation of Heterocycles Based Chalcone Derivatives as Antiproliferative Agents

Volume:18
Betul Kaya, Ozlem Atli, Gozde Gormus, Yusuf Ozkay* and Zafer Asim Kaplancikli

Coumarin Derivatives as Anticancer Agents for Lung Cancer Therapy: A Review

Volume:18
Manvendra Kumar, Ramit Singla, Jyoti Dandriyal and Vikas Jaitak*

Synthesis, Spectral Characterization, Antibacterial and Anticancer Activity of some Titanium Complexes

Volume:18
Raj Kaushal*, Nitesh Kumar, Archana Thakur, Kiran Nehra, Pamita Awasthi, Rajeev Kaushal and Saroj Arora

A Review on the Management of Small Renal Masses: Active Surveillance Versus Surgery

Volume:17
Giancarlo Marra, Marco Oderda, Marco Allasia, Stefania Munegato, Steven Joniau and Paolo Gontero

Pre-clinical Validation of Mito-targeted Nano-engineered Flavonoids Isolated From Selaginella bryopteris (Sanjeevani) As A Novel Cancer Prevention Strategy

Volume:18
Arpit Bhargava, Neelam Pathak, Sriram Seshadri, Neha Bunkar, Subodh Kumar Jain, Dinesh Mishra Kumar, Nirmal Kumar Lohiya and Pradyumna Kumar Mishra*

Determination of the Apoptotic Effect and Molecular Docking of Benzamide Derivative XT5 in K562 Cells

Volume:18
Tulin Ozkan, Yalda Hekmatshoar*, Tugba Ertan-Bolelli, Andry Nur Hidayat, Meral Beksac, Esin Aki-Yalcin, Ismail Yalcin and Asuman Sunguroglu

Astragalin Attenuates UVB Radiation-induced Actinic Keratosis Formation

Volume:18
Jian Zhang*, Na Li, Kun Zhang, Ping Pan, Hui Zhang, Ning Li, Qiong Tian, Li Zhang, Wenli Liu, Tianyuan Gao, Xin Mu, Dengchao Feng, Wei Guo and Xiaona Ma

Emodin Enhances the Chemosensitivity of Endometrial Cancer by Inhibiting ROS-Mediated Cisplatin-resistance

Volume:18
Ning Ding, Hong Zhang, Shan Su, Yumei Ding, Xiaohui Yu, Yujie Tang, Qingfang Wang and Peishu Liu*

ROS-scavenging and Anti-tyrosinase Properties of Crocetin on B16F10 Murine Melanoma Cells

Volume:18
Seyed Hamed Hashemi-Shahri, Alireza Golshan, Seyed Ahmad Mohajeri, Javad Baharara, Elaheh Amini, Farzaneh Salek, Amirhossein Sahebkar* and Zahra Tayarani-Najaran

The Effect of Flubendazole on Adhesion and Migration in SW480 and SW620 Colon Cancer Cells

Volume:18
Veronika Hanusova*, Lenka Skalova, Vera Kralova and Petra Matouskovs

Inhibition of Intercellular Communication between Prostate Cancer Cells by a Specific Anti-STEAP-1 Single Chain Antibody

Volume:18
Seyed-Alireza Esmaeili, Foroogh Nejatollahi* and Amirhossein Sahebkar

A Newly Synthetized Ferrocenyl Derivative Selectively Induces Apoptosis in ALL Lymphocytes through Mitochondrial Estrogen Receptors

Volume:18
Marjan Aghvami, Jalal Pourahmad*, Afshin Zarghi, Peyman Eshghi, Mohammad Hadi Zarei, Shabnam Farzaneh and Fatemeh Sattari

Synthesis and Evaluation of a New Series of Arylidene Indanones as Potential Anticancer Agents

Volume:18
Ahmet Ozdemir*, Sevtem Gokbulut, Belgin Sever, Gulsen Akalın Ciftci and Mehlika Dilek Altıntop

Design, Synthesis and Anti-breast Cancer Activity of Some Novel Substituted Isoxazoles as Anti-breast Cancer Agent

Volume:18
Santosh N Mokale*, Nikhil S Sakle, Swati A Bhavale, Deepak K Lokwani and Vishakha Shelke

Trichinella spiralis and Tumors: Cause, Coincidence or Treatment?

Volume:17
Chengshui Liao*, Xiangchao Cheng, Mingyuan Liu, Xuelin Wang and Pascal Boireau

A Comparison of Fucoidan Conjugated to Paclitaxel and Curcumin for the Dual Delivery of Cancer Therapeutic Agents

Volume:17
Nam Hoang Phan , Thao Thanh Ly, Minh Nguyet Pham , Thinh Duc Luu , Toi Van Vo , Phuong Ha-Lien Tran* and Thao Truong-Dinh Tran

Ganoderma lucidum Polysaccharides as An Anti-cancer Agent

Volume:17
Didem Sohretoglu* and Shile Huang

Modulation of Cancer Metabolism by Phytochemicals - A Brief Overview

Volume:17
Danina M. Muntean, Sturza Adrian*, Ioana Pavel and Oana Duicu

The Clinical and Experimental Research on the Treatment of Endometriosis with Thiostrepton

Volume:18
Ping Jin*, Fei Xiao CHEN, Yang Zi Li, Qing Qing Zhang and Jian Zhang

Anticancer Activity of Resorcinarene-PAMAM-Dendrimer Conjugates of Flutamide

Volume:18
Luis D. Pedro-Hernandez, Elena Martinez Klimova*, Mark Eugenii Martínez-Klimov, Sandra Cortez-Maya, Ana Cristina Vargas-Medina, Teresa Ramirez-Apan, Simon Hernandez-Ortega and Marcos Martínez-Garcia

Design, Synthesis and Cytotoxicity Evaluation of New 3, 5-Disubstituted-2- Thioxoimidazolidinones

Volume:18
Khaled Abdellatif*, Mostafa M Elbadawi, Mohammed T Elsaady, Amer Ali Abd El-Hafeez, Takashi Fujimura, Seiji Kawamoto and Ahmed I Khodair

Natural Compounds in the Chemoprevention of Malignant Melanoma

Volume:17
Corina Danciu *, Codruta Soica, Diana Antal, Alexa Ersilia , Roxana Ghiulai , Ioana Pavel , Florina Ardelean, Roxana Babuta, Alexandra Popescu and Cristina Dehelean

Selecting Patients with Small Renal Masses for Active Surveillance

Volume:17
Michael H Johnson, Mohamad E Allaf and Phillip M Pierorazio*

Halilectin-3, a Lectin from the Marine Sponge Haliclona caerulea, Induces Apoptosis and Autophagy in Human Breast Cancer MCF7 Cells Through Caspase-9 Pathway and LC3-II Protein Expression

Volume:17
Luiz Gonzaga do Nascimento-Neto, Maria Guadalupe Cabral, Romulo Farias Carneiro, Zelia Silva, Francisco Vassiliepe Sousa Arruda, Celso Shiniti Nagano, Alexandra R Fernandes, Alexandre Holanda Sampaio, Edson Holanda Teixeira* and Paula Alexandra Videira*

Antineoplastic Effects of NF-

Volume:17
Priscila Maria Manzini Ramos*, Julia Alejandra Pezuk, Angel Mauricio Castro-Gamero, Harley Francisco de Oliveira, Carlos Alberto Scrideli, Kazuo Umezawa and Luiz Gonzaga Tone

Recent Development of Sulfonyl or Sulfonamide Hybrids as Potential Anticancer Agents: A Key Review

Volume:17
K. P. Rakesh, Shi-Meng Wang, Jing Leng, L Ravindar, Abdullah M Asiri, Hadi M Marwani and Hua-Li Qin*

A Review of Electroporation-based Antitumor Skin Therapies and Investigation of Betulinic Acid-loaded Ointment

Volume:17
Monika Bakonyi*, Szilvia Berko, Gabor Eros, Gabor Varju, Cristina Dehelean, Maria Budai Szucs and Erzsebet Csanyi