Anti-Cancer Agents in Medicinal Chemistry

(Formerly Current Medicinal Chemistry - Anti-Cancer Agents)

This journal supports open access

Editor-in-Chief:

Michelle Prudhomme
Institut de Chimie de Clermont-Ferrand
ICCF-CNRS UMR 6296
Université Clermont Auvergne
Clermont-Ferrand
France

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Articles Ahead of Print

Evaluation of Angiogenesis Process after Metformin and LY294002 Treatment in Mammary Tumor

Volume:19
Marina Gobbe Moschetta, Camila Leonel, Larissa Bazela Maschio-Signorini, Thaiz Ferraz Borin, Gabriela Bottaro Gelaleti, Bruna Victorasso Jardim-Perassi, Lívia Carvalho Ferreira, Nathália Martins Sonehara, Livia Gabriélle Silva Carvalho, Eva Hellmén and Debora Aparecida Pires de Campos Zuccari*

Cytotoxic Action of N-aryl, Furan-derived Aminophosphonates against HT29 and HCT116 Cancer Cell Lines

Volume:19
Jarosław Lewkowski*, Edyta Rzeszotarska, Agnieszka Matusiak, Marta Morawska, Gabriela Gajek, Karolina Nowak and Renata Kontek*

Determination of Usnic Acid Responsive miRNAs in Breast Cancer Cell Lines

Volume:18
Nil Kiliç, Yasemin Oztemur Islakoglu, İlker Buyuk, Bala Gur-Dedeoglu and Demet Cansaran-Duman*

Poly (ADP-Ribose) Polymerases (PARPs) and PARP Inhibitor-Targeted Therapeutics

Volume:18
Nan Li*, Yifan Wang, Weiye Deng and Steven Hsesheng Lin*

Selective Photodynamic Effects on Breast Cancer Cells Provided by P123 Pluronic®- Based Nanoparticles Modulating Hypericin Delivery

Volume:18
Gabrielle Marconi Zago Ferreira Damke, Raquel Pantarotto Souza, Maiara Camotti Montanha, Edilson Damke, Renato Sonchini Gonçalves, Gabriel Batista Cesar, Elza Kimura, Wilker Caetano, Noboru Hioka and Marcia Edilaine Lopes Consolaro*

Antitumor Potential of Berberine and Cinnamic Acid against Solid Ehrlich Carcinoma in Mice

Volume:18
Rafa S. Almeer, Ahmed M. Aref, Romisa A. Hussein, Mohamed S. Othman and Ahmed E. Abdel Moneim*

Peptide R18H from Brn-2 Transcription Factor POU Domain Displays Antitumor Activity In Vitro and In Vivo And Induces Apoptosis in B16F10-Nex2 Cells

Volume:18
Fernanda Fernandes Miranda da Cunha, Katia Cristina Ugolini Mugnol, Filipe Menegatti de Melo , Marta Verônica da Silva Queiroz Nascimento, Ricardo Alexandre de Azevedo, Raquel Tamires Soares Santos, Jéssica Aparecida Magalhães, Danilo Ciccone Miguel , Dayane Batista Tada, Renato Arruda Mortara, Luiz Rodolpho Travassos and Denise Costa Arruda*

Phytochemicals in Anticancer Drug Development

Volume:18
Rohit Dutt, Vandana Garg, Naveen Khatri and A. K. Madan*

[10]-Gingerol Affects Multiple Metastatic Processes and Induces Apoptosis in MDAMB- 231 Breast Tumor Cells

Volume:18
Angelina M. Fuzer, Ana Carolina B. M. Martin, Amanda B. Becceneri, James A. da Silva, Paulo C. Vieira and Marcia R. Cominetti*

Crocetin and Crocin from Saffron in Cancer Chemotherapy and Chemoprevention

Volume:19
Claudio Festuccia*, Alessandro Colapietro, Andrea Mancini and Annamaria D'alessandro

The Anticancer Role of Omega-3 Polyunsaturated Fatty Acids was Closely Associated with the Increase in Genomic DNA Hydroxymethylation

Volume:18
Qionglin Huang, Mingming Mo, Yu Zhong, Qingjin Yang, Junjie Zhang, Xiaoxia Ye, Lijian Zhang and Chun Cai*

Verbascoside Attenuates Rac-1 and HIF-1α Signaling Cascade in Colorectal Cancer Cells

Volume:18
Danial Seyfi, Seyed Bahram Behzad, Mohammad Nabiuni*, Kazem Parivar, Mohammad Tahmaseb and Elaheh Amini

Alkylphospholipids are Signal Transduction Modulators with Potential for Anticancer Therapy

Volume:18
Martin Berger*, Ferda Kaleagasıoglu, Maya Margaritova Zaharieva and Spiro M. Konstantinov

Modulation of Mitochondrial and Epigenetic Targets by Polyphenols-rich Extract from Araucaria angustifolia in Larynx Carcinoma

Volume:18
Catia Santos Branco*, Angela Duong, Alencar K Machado, Gustavo Scola, Ana C Andreazza and Mirian Salvador

MMP7 Induces T-DM1 Resistance and Leads to the Poor Prognosis of Gastric Adenocarcinoma via a DKK1-Dependent Manner

Volume:19
Hua Li, Xin Xu, Yang Liu, Shunle Li, Di Zhang, Xiaofen Meng, Le Lu and Yiming Li*

HOXA4-Dependent Transcriptional Activation of AXL Promotes Cisplatin- Resistance in Lung Adenocarcinoma Cells

Volume:19
Shuo Yu, Hui Ren, Yang Li, Xuan Liang, Qian Ning, Xue Chen, Mingwei Chen and Tinghua Hu*

Can Combined Therapy Benefit Immune Checkpoint Blockade Response in Hepatocellular Carcinoma?

Volume:18
Fan Zhongqi, Sun Xiaodong, Chen Yuguo and Lv Guoyue*

Hybrid Magnetic Nanostructures For Cancer Diagnosis And Therapy

Volume:18
Ardelean Lavinia Ioana, Denisa Ficai*, Maria Sonmez, Mihail Aurel Titu, Ovidiu Oprea, Gheorghe Nechifor, Anton Ficai and Ecaterina Andronescu

Computational Studies in Drug Design Against Cancer

Volume:18
Baishakhi De, Koushik Bhandari, Francisco J. B. Mendonça, Marcus Tullius Scotti and Luciana Scotti*

What Makes Species Productive of Anti-Cancer Drugs? Clues from Drugs’ Species Origin, Druglikeness, Target and Pathway

Volume:18
Xiaofeng Li, Xiaoxu Li, Yinghong Li, Chunyan Yu, Weiwei Xue, Jie Hu*, Bo Li, Panpan Wang and Feng Zhu*

Phage Display Technology and its Applications in Cancer Immunotherapy

Volume:18
Yicun Wang, Yang Lin and Jiayin Lv*

Biological Activity and Physicochemical Properties of Dipeptidyl Nitrile Derivatives Against Pancreatic Ductal Adenocarcinoma Cells

Volume:18
José Carlos Quilles, Murillo Dorileo Leite Bernardi, Pedro Henrique Jatai Batista, Samelyn da Costa Martins Silva, Camila de Melo Romero Rocha, Carlos Alberto Montanari and Andrei Leitão*

Synthesis of Asymmetric 1-Thiocarbamoyl Pyrazoles as Potent Anti- Colon Cancer, Antioxidant and Anti-Inflammatory Agent

Volume:18
Dattatraya G. Raut, Sandeep B. Patil, Vikas D. Kadu, Mahesh G. Hublikar and Raghunath B. Bhosale*

Hydroxyl Group Difference between Anthraquinone Derivatives Regulate Different Cell Death Pathways via Nucleo-Cytoplasmic Shuttling of p53

Volume:18
Mohd Kamil, Ejazul Haque, Snober S. Mir*, Safia Irfan, Adria Hasan, Saba Sheikh, Shamshad Alam, Kausar Mahmood Ansari and Aamir Nazir

Evaluation of A Novel GLP-1R Ligand for PET Imaging of Prostate Cancer

Volume:18
Yuanyuan Yue, Yuping Xu, Lirong Huang, Donghui Pan, Zhicheng Bai, Lizhen Wang, Runlin Yang, Junjie Yan, Huizhu Song*, Xiaotian Li and Min Yang

Spectroscopic and In Silico DNA Binding Studies on the Interaction of Some New N-Substituted Rhodanines with Calf-thymus DNA: In Vitro Anticancer Activities

Volume:18
Imran Ali*, Mohammad Nadeem Lone, Zeid A. Alothman, Ahmad Yacine Badjah and Abdullah G. Alanazi

Enasidenib: First Mutant IDH2 Inhibitor for the Treatment of Refractory and Relapsed Acute Myeloid Leukemia

Volume:18
Raghav Dogra, Rohit Bhatia, Ravi Shankar, Parveen Bansal and Ravindra K. Rawal*

A Review on the Role of VEGF In Tamoxifen Resistance

Volume:18
Sepideh Mansouri, Nikta Feizi, Ali Mahdi, Keivan Majidzadeh-A and Leila Farahmand*

Pinocembrin-Enriched Fractions of Elytranthe parasitica (L.) Danser Modulates Apoptotic and MAPK Cellular Signaling in HepG2 Cells

Volume:18
Nimmy Kumar, Akhila Hosur Shrungeswara, Sanchari Basu Mallik, Subhankar Biswas, A Jesil Mathew , K. Nandakumar, Jessy Mathew and Richard Lobo*

Design, Synthesis, In vitro Cytotoxic Activity Evaluation, and Study of Apoptosis Inducing Effect of New Styrylimidazo[1,2-a]Pyridines as Potent Anti-Breast Cancer Agents

Volume:18
Faeze Khalili, Sara Akrami, Malihe Safavi, Maryam Mohammadi-Khanaposhtanid, Mina Saeedi, Sussan Kabudanian Ardestani, Bagher Larijani, Afsaneh Zonouzi*, Maliheh Barazandeh Tehrani* and Mohammad Mahdavi*

Virtual Screening of Anti-Cancer Compounds: Application of Monte Carlo Technique

Volume:18
Alla P. Toropova*, Andrey A. Toropov, Emilio Benfenati, Danuta Leszczynska and Jerzy Leszczynski

Gedunin, A Neem Limonoid in Combination with Epalrestat Inhibits Cancer Hallmarks by Attenuating Aldose Reductase-Driven Oncogenic Signaling in SCC131 Oral Cancer Cells

Volume:18
T Kiran Kishore Kranthi , Abdul Basit Baba, Jaganathan Kowshik, G. Bhanuprakash Reddy and Siddavaram Nagini*

New Strategies for Therapeutic Cancer Vaccines

Volume:18
Jiyao Sheng, Hanjiao Qin, Dan Zhang, Xuewen Zhang, Linlin Liu and Bingjin Li*

Silimarin and Cancer

Volume:18
Christina Liakopoulou, Christos Kazazis and Natalia G. Vallianou*

Chlorambucil Cytotoxicity Reduction in Rats Through Bone Marrow, An In vivo Study

Volume:18
Ebtesam H.O. Nafie*, Eman Khater, Mohamed Awwad, Mohamed Zowail and Kholud Hegazy

Synthesis and Investigation of the Role of Benzopyran Dihydropyrimidinone Hybrids in Cell Proliferation, Migration and Tumor Growth

Volume:18
Ashutosh K. Dash, Debasis Nayak, Nazar Hussain, Mubashir Javed Mintoo, Sumera Bano, Archana Katoch, Dilip Manikaro Mondhe, Anindya Goswami and Debaraj Mukherjee*

Protective Effects of Downregulating Estrogen Receptor Alpha Expression in Cervical Cancer

Volume:18
Ping Yu, Yuping Wang, Chuanxun Li, Li Lv* and Jihong Wang*

Celastrus Orbiculatus Extract Potentiates The Sensitivity Of Cisplatin Via Caspase-Depenent Apoptosis In Gastric Cancer

Volume:18
Weimin Wang, Yan Zhou, Qiang Yao, Weihua Liu, Liangliang Xiang, Tengyang Ni, Xiaojun Dai and Yanqing Liu*

A Comparison of the Inhibitory Effects of Anti-Cancer Drugs on Thioredoxin Reductase and Glutathione S-Transferase in Rat Liver

Volume:18
Ilknur Ozgencli, Deryanur Kilic, Ugur Guller, Mehmet Ciftci, Omer Irfan Kufrevioglu and Harun Budak*

Xanthone Conjugated Amino Acids as Potential Anticancer and DNA Binding Agents: Molecular Docking, Cytotoxicity and SAR Studies

Volume:18
K. P. Rakesh, N. Darshini, H. M. Manukumar, H. K. Vivek, D. S. Prasanna* and N. Mallesha*

Arsenic Trioxide and Artemisinin Act Synergistically To Kill Tumor Cells In vitro

Volume:18
Xiaoyan Zhao*, Sen Yang, Duoduo Zhang, Zhubo Li and Chengzhi Huang*

Pleiotropic Effect of Mahanine and Girinimbine Analogs: Anticancer Mechanism and its Therapeutic Versatility

Volume:18
V. L. Maruthanila, R. Elancheran*, A. B. Kunnumakkara, S. Kabilan and Jibon Kotoky*

Aberrant Sialylation in Cancer Pathology and Metastasis, a Putative Drug Target Candidate

Volume:18
Da-Yong Lu, Ting-Ren Lu, Bin Xu, Min Huang, Hong Zhu, Ying Shen and Nagendra Sastry Yarla

Biomarkers in Non-Small Cell Lung Cancer: Perspectives of Individualized Targeted Therapy

Volume:18
Mateus Nobrega Aoki*, Marla Karine Amarante, Carlos Eduardo Coral de Oliveira and Maria Angelica Ehara Watanabe

Design, Synthesis, and Preliminary Bioactivity Evaluation of 2,7-Substituted Carbazole Derivatives as Potent Autotaxin Inhibitors and Antitumor Agents

Volume:18
Wenming Wang, Fengmei Zhao, Yarui Zhao, Weiwei Pan, Pengcheng Cao, Lintao Wu , Zhijun Wang, Xuan Zhao, Yi Zhao* and Hongfei Wang*

Critical microRNAs in Lung Cancer: Recent Advances and potential Applications

Volume:18
Habib Zarredar, Khalil Ansarin, Behzad Baradaran, Najibeh Shekari, Shirin Eyvazi , Fateme Safari and Safar Farajnia*

The Role of Heat Shock Proteins in Cisplatin Resistance

Volume:18
Zdzislaw Krawczyk, Agnieszka Gogler-Pigłowska, Damian Robert Sojka and Dorota Scieglinska*

Engineered Silver Nanoparticles, A New Nanoweapon Against Cancer

Volume:18
Mohammad Ali Ebrahimzadeh, Alireza Tafazoli, Javad Akhtari, Pourya Biparva and Shahram Eslami*

Immunotherapy in Patients with Recurrent and Metastatic Squamous Cell Carcinoma of the Head and Neck

Volume:18
Izabela Lasinska*, Tomasz Kolenda, Anna Teresiak, Katarzyna M. Lamperska, Lukasz Galus and Jacek Mackiewicz

Cancer Nanotechnology-An Excursion on Drug Delivery Systems

Volume:18
Mala Sharma, Chitranshu Pandey, Neha Sharma, M. A. Kamal, Usman Sayeed and Salman Akhtar*

Insights into the Biological Evaluation of Pterocarpanquinones and Carbapterocarpans with Anti-tumor Activity against MDR Leukemias

Volume:18
Vivian M Rumjanek*, Raquel C Maia, Eduardo J Salustiano and Paulo R. R. Costa

Metal Complexes of Natural Product Like-compounds with Antitumor Activity

Volume:18
Beatriz de las Heras, Angel Amesty, Ana Estevez-Braun and Sonsoles Hortelano*

Growth Kinetics and Oncologic Outcomes for Small Renal Masses Managed with Active Surveillance: A Review of the Literature

Volume:17
Benjamin T Ristau*, Thomas W Fuller, Ricardo Rios, Cristina Ho and Jeffrey J Tomaszewski

The Clinical and Experimental Research on the Treatment of Endometriosis with Thiostrepton

Volume:18
Ping Jin*, Fei Xiao CHEN, Yang Zi Li, Qing Qing Zhang and Jian Zhang