Anti-Cancer Agents in Medicinal Chemistry

(Formerly Current Medicinal Chemistry - Anti-Cancer Agents)

This journal supports open access

Editor-in-Chief:

Michelle Prudhomme
Institut de Chimie de Clermont-Ferrand
ICCF-CNRS UMR 6296
Université Clermont Auvergne
Clermont-Ferrand
France

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Articles Ahead of Print

The Correlation between EGFR and Androgen Receptor Pathways: A Novel Potential Prognostic Marker in Gastric Cancer

Volume:19
Shahrzad S. Fard, Kioomars Saliminejad, Masoud Sotoudeh, Niloofar Soleimanifard, Shaghayegh Kouchaki, Mansour Yazdanbod, Habibollah Mahmoodzadeh, Ardeshir Ghavamzadeh, Reza Malekzadeh, Bahram Chahardouli, Kamran Alimoghaddam* and Seyed H. Ghaffari*

Inhibition of Cancer Stem-Like Phenotype by Curcumin and Deguelin in CAL-62 Anaplastic Thyroid Cancer Cells

Volume:19
Mehmet A. Kocdor*, Hakan Cengiz, Halil Ates and Hilal Kocdor

Three Pt-Pt Complexes with Donor-Acceptor Feature: Anticancer Activity, DNA Binding Studies and Molecular Docking Simulation

Volume:19
Pezhman Ashoo, Reza Yousefi*, S. Masoud Nabavizadeh, Marzieh Dadkhah Aseman, Sareh Paziresh, Atiyeh Ghasemi and Ali Akbar Saboury

Berberine as Source of Antiproliferative Hybrid Compounds: In Vitro Antiproliferative Activity and Quantitative Structure-Activity Relationship

Volume:19
Mario Alberto Leyva-Peraltaa, Ramón Enrique Robles-Zepedab, Rodrigo Said Razo-Hernándezc, Laura Patricia Álvarez Berberd, Karen Ochoa Laraa, Eduardo Ruiz-Bustosb and Juan Carlos Gálvez-Ruízb*

Dehydroandrographolide Inhibits Osteosarcoma Cell Growth and Metastasis by Targeting SATB2-Mediated EMT

Volume:19
Xuefeng Liu, Yonggang Fan, Jing Xie, Li Zhang, Zhenyuan Wang* and Lihua Li*

STK33-Dependent Transcriptional Regulation of SFTA3 Induces Cisplatin- Resistance in Lung Adenocarcinoma

Volume:19
Kuilong Zhou, Runzhi Dong, Zhiheng Wang, Zhian Tang, Xuezhen Gao, Yaqing Du, Xiaoli Zhang, Xiangying Li and Qingfan Xie*

The Pharmacogenomics “Side-effect” of TP53/EGFR in Non-small Cell Lung Cancer Accompanied with Atorvastatin Therapy: A Functional Network Analysis

Volume:19
Lei Zhang, Yifang Huang, Xuedong Gan, Siying He, Xiaohuan Cheng, Na Yang, Siwei Li, Zuhua Li and Fang Zheng*

Pyrrolo[1,2-a]azepines Coupled with Benzothiazole and Fluorinated Aryl Thiourea Scaffolds as Promising Antioxidant and Anticancer Agents

Volume:19
Rahul V. Patel*, Bhupendra M. Mistry, Riyaz Syed, Nikhil M. Parekh and Han-Seung Shin

Synthesis and Anticancer Activity of Benzimidazole/Benzoxazole Substituted Triazolotriazines in Hepatocellular Carcinoma

Volume:19
Sakineh Dadashpour, Tuba T. Küçükkılınç, Ayse Ercan, Seyed J. Hosseinimehr, Nima Naderi and Hamid Irannejad*

Jab1-siRNA Induces Cell Growth Inhibition and Cell Cycle Arrest in Gall Bladder Cancer Cells via Targeting Jab1 Signalosome

Volume:19
Pratibha Pandey, Mohammad H. Siddiqui, Anu Behari, V.K. Kapoor, Kumudesh Mishra, Uzma Sayyed, Rohit K. Tiwari, Rafia Shekh and Preeti Bajpai*

Lemon Juice Mediated Synthesis of 3-Substituted Quinazolin-4(3H)-Ones and their Pharmacological Evaluation

Volume:19
Malavattu G. Prasad, C. Vijaya Lakshmi, Naresh K. Katari*, Rajshekhar Karpoormath and Manojit Pal

An Approach to Treatment of Liver Cancer by Novel Glycyrrhizin Derivative

Volume:19
Fardous F. El-Senduny, Mahmoud M. Zidane, Magdy Mahfouz Youssef and Farid A. Badria*

Iodine Bonded with Milk Protein Inhibits Benign Prostatic Hyperplasia Development in Rats

Volume:19
Vladimir G. Bespalov*, Valerii A. Alexandrov, Grigory V. Tochilnikov, Dmitrii Е. Lukin, Nadezhda T. Zhilinskaya, Alexandr L. Semenov, Irina N. Vasilyeva, Vladimir A. Romanov, Irina A. Tumanyan, Elena D. Ermakova, Elizaveta I. Kovalevskaya, Nadezhda V. Barakova and Denis A. Baranenko

Zinc Finger Nuclease Combines with Cisplatin and Trichostatin A Enhances the Antitumor Potency in Cervical Cancer Cells

Volume:18
Ci Ren, Chun Gao, Xiaomin Li, Hui Shen, Liming Wang, Da Zhu, Peng Wu, Ding Ma, Hui Wang* and Wencheng Ding*

New Derivatives of Bacteriopurpurin with Thiolated Au (I) Complexes: Dual Darkand Light Activated Antitumor Potency

Volume:19
Mikhail A. Grin*, Sergei I. Tikhonov, Albina S. Petrova, Victor A. Pogorilyy, Аlexey N. Noev, Victor V. Tatarskiy, Dmitry B. Shpakovsky, Elena R. Milaeva, Elena V. Kalinina, Nikolai N. Chernov, Аlexander А. Shtil, Andrei F. Mironov, Andrei D. Kaprin and Elena V. Filonenko

Celastrus Orbiculatus Extracts Inhibit the Metastasis through Attenuating PI3K/Akt/mTOR Signaling Pathway in Human Gastric Cancer

Volume:19
Yayun Qian, Yan Yan, Hongmei Lu, Tingting Zhou, Mengying Lv, Chuanci Fang, Jingjing Hou, Wenyuan Li, Xiwen Chen, Hui Sun, Yajuan Li, Zheng Wang, Nan Zhao, Yajuan Gu, Yongling Ding* and Yanqing Liu*

Design, In Silico Modelling, and Functionality Theory of Novel Folate Receptor Targeted Rutin Encapsulated Folic Acid Conjugated Keratin Nanoparticles for Effective Cancer Treatment

Volume:19
Selvaraj Kunjiappan, Theivendren Panneerselvam*, Saravanan Govindaraj, Pavadai Parasuraman, Suraj Baskararaj, Murugesan Sankaranarayanan, Sankarganesh Arunachalam, Ewa Babkiewicz, Aarthi Jeyakumar and Muthulakshmi Lakshmanan

The Effect of a Ferrocene Containing Camphor Sulfonamide DK-164 on Breast Cancer Cell Lines

Volume:19
Maria Schröder, Shazie Yusein-Myashkova, Maria Petrova, Georgi Dobrikov, Mariana Kamenova-Nacheva, Jordana Todorova, Evdokia Pasheva and Iva Ugrinova

Quercetin Loaded Nanoparticles in Targeting Cancer: Recent Development

Volume:19
Manjula Vinayak* and Akhilendra K. Maurya

Ginsenoside Rh2 Inhibits Migration of Lung Cancer Cells Under Hypoxia via mir-491

Volume:19
Yingying Chen, Yuqiang Zhang, Wei Song, Ying Zhang, Xiu Dong and Mingqi Tan

Design, Synthesis and Biological Evaluation of Novel N-hydroxyheptanamides Incorporating 6-hydroxy-2-methylquinazolin-4(3H)-ones as Histone Deacetylase Inhibitors and Cytotoxic Agents

Volume:19
Nguyen V. Minh, Nguyen T. Thanh, Hoang T. Lien, Dinh T.P. Anh, Ho D. Cuong, Nguyen H. Nam, Pham T. Hai, Le Minh-Ngoc, Huong Le-Thi-Thu, Luu V. Chinh and Tran K. Vu*

Synthesis of 5-Alknyltetrandrine Derivatives and Evaluation of Their Anticancer Activity on A549 Cell Lines

Volume:19
Nana Niu, Tingli Qu, Jinfang Xu, Xiaolin Lu, Graham J. Bodwell* and Zhengbao Zhao

Hydroxytyrosol and Oleuropein Inhibit Migration and Invasion of MDA-MB-231 Triple-Negative Breast Cancer Cell via Induction of Autophagy

Volume:19
Hui-Yuan Lu*, Jian-Sheng Zhu, Zhan Zhang, Wei-Jian Shen, Shan Jiang, Yun-Feng Long, Bin Wu, Tao Ding, Fei Huan and Shou-Lin Wang

Nanoliposomal Encapsulation Enhances In Vivo Anti-Tumor Activity of Niclosamide against Melanoma

Volume:19
Mahdi Hatamipour, Mahmoud R. Jaafari, Amir A. Momtazi-Borojeni, Mahin Ramezani and Amirhossein Sahebkar*

Glucosamine Protects Rat Bone Marrow Cells Against Cisplatin-Induced Genotoxicity and Cytotoxicity

Volume:19
Mohsen Cheki*, Salman Jafari, Masoud Najafi and Aziz Mahmoudzadeh

Overcoming Cancer Cell Drug Resistance by a Folic Acid Targeted Polymeric Conjugate of Buthionine Sulfoximine

Volume:19
Felisa Cilurzo, Maria C. Cristiano, Marta Da Pian, Eleonora Cianflone, Luigi Quintieri*, Donatella Paolino and Gianfranco Pasut*

Correlation between Antioxidant/Antimutagenic and Antiproliferative Activity of Some Phytochemicals

Volume:19
Doaa T. Ramadan, Mohamed A. Ali, Shaymaa M. Yahya and Wael M. El-Sayed*

Recent Advances of Silver Nanoparticles in Cancer Diagnosis and Treatment

Volume:19
Tran Q. Huy*, Pham T.M. Huyen, Anh-Tuan Le and Matteo Tonezzer

ESM-1: A Novel Tumor Biomaker and its Research Advances

Volume:19
Chen Li, Hui Geng*, Linhua Ji, Xiaojing Ma, Qichao Yin and Hua Xiong

Apigenin-mediated Alterations in Viability and Senescence of SW480 Colorectal Cancer Cells Persist in The Presence of L-thyroxine

Volume:19
Zohreh Bagheri, Masoumeh Varedi*, Fakhraddin Naghibalhossaini and Gholam H R. Omrani

Cranberry: A Promising Natural Source of Potential Nutraceuticals with Anticancer Activity

Volume:19
Maria Mantzorou*, Apostolos Zarros, Stamatios Theocharis, Eleni Pavlidou and Constantinos Giaginis

The Perplexity of Synergistic Duality: Inter-Molecular Mechanisms of Communication in BCR-ABL1

Volume:19
Ahmed A. Elrashedy, Pritika Ramharack and Mahmoud E.S. Soliman*

Natural Compounds Targeting Cancer Stem Cells: A Promising Resource for Chemotherapy

Volume:19
Plabon K. Das, Tasnim Zahan, Md. Abdur Rakib, Jahan A. Khanam, Suja Pillai and Farhadul Islam*

COX-2 Docking Structural Analysis with Phytochemical Extracts of Rosemary: A Possible Cytotoxicity on Head and Neck Squamous Cell Carcinoma Cell Line (HEp-2)

Volume:19
Ihab S. Abd El-Hamid *, Yara Y. Mouselhy, Marwa M. El-Shafei, Marwa M. Sayed, Aly F. Mohamed and Doaa B. Farag

Hypoxia-inducible Factor-1α Mediates Hyperglycemia-induced Pancreatic Cancer Glycolysis

Volume:19
Liang Cheng, Tao Qin, Jiguang Ma, Wanxing Duan, Qinhong Xu, Xuqi Li, Liang Han, Wei Li, Zheng Wang, Dong Zhang, Qingyong Ma* and Jianjun Lei*

An Inventive Report of Inducing Apoptosis in Non-Small Cell Lung Cancer (NSCLC) Cell Lines by Transfection of MiR-4301

Volume:19
Abbas Jamshidi Avval, Ahmad Majd, Naghmeh Gholipour, Kambiz Akbari Noghabi, Anna Ohradanova-Repic and Ghasem Ahangari*

Anti-Tumor Mechanisms of Novel 3-(4-Substituted Benzyl)-5-Isopropil-5- Phenylhydantoin Derivatives in Human Colon Cancer Cell Line

Volume:19
Ana Obradovića, Miloš Matića, Branka Ognjanovića, Nenad Vukovićb, Milena Vukićb, Predrag Djurdjevic, Gordana Ušćumlićd, Bojan Božiće and Biljana Božić Nedeljkoviće*

Transcriptome Analysis of mRNA in Uterine Leiomyoma Using Next-Generation RNA Sequencing

Volume:19
Shadab Anjum, Tahreem Sahar, Aruna Nigam and Saima Wajid*

Contribution of Major Polyphenols to the Antioxidant Profile and Cytotoxic Activity of Olive Leaves

Volume:19
Zouhaier Bouallagui*, Asma Mahmoudi, Amina Maalej, Fatma Hadrich, Hiroko Isoda and Sami Sayadi

The Opposite Effect of L-kynurenine and Ahr Inhibitor Ch223191 on Apoptotic Protein Expression in Pancreatic Carcinoma Cells (Panc-1)

Volume:19
Anna Leja-Szpak*, Marta Góralska, Paweł Link-Lenczowski, Urszula Czech, Katarzyna Nawrot-Porąbka, Joanna Bonior and Jolanta Jaworek

Influence of New Synthetic Xanthones on the Proliferation and Migration Potential of Cancer Cell Lines in vitro

Volume:19
Natalia Szkaradek*, Daniel Sypniewski, Dorota Żelaszczyk, Sabina Gałka, Paulina Borzdziłowska, Henryk Marona and Ilona Bednarek

Determination of Usnic Acid Responsive miRNAs in Breast Cancer Cell Lines

Volume:18
Nil Kiliç, Yasemin Oztemur Islakoglu, İlker Buyuk, Bala Gur-Dedeoglu and Demet Cansaran-Duman*

Selective Photodynamic Effects on Breast Cancer Cells Provided by P123 Pluronic®- Based Nanoparticles Modulating Hypericin Delivery

Volume:18
Gabrielle Marconi Zago Ferreira Damke, Raquel Pantarotto Souza, Maiara Camotti Montanha, Edilson Damke, Renato Sonchini Gonçalves, Gabriel Batista Cesar, Elza Kimura, Wilker Caetano, Noboru Hioka and Marcia Edilaine Lopes Consolaro*

Growth Kinetics and Oncologic Outcomes for Small Renal Masses Managed with Active Surveillance: A Review of the Literature

Volume:17
Benjamin T Ristau*, Thomas W Fuller, Ricardo Rios, Cristina Ho and Jeffrey J Tomaszewski