Anti-Cancer Agents in Medicinal Chemistry

(Formerly Current Medicinal Chemistry - Anti-Cancer Agents)

This journal supports open access

Editor-in-Chief:

Michelle Prudhomme
Institut de Chimie de Clermont-Ferrand
ICCF-CNRS UMR 6296
Université Clermont Auvergne
Clermont-Ferrand
France

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Editorial (Hot Topic: Inhibition of PI3K/Akt/mTOR Signaling by Natural Products) free to download

Volume:13   Issue:7
Pp: 967-970
Shile Huang
DOI: 10.2174/1871520611313070001

Targeting the PI3K/Akt/mTOR Axis by Apigenin for Cancer Prevention

Volume:13   Issue:7
Pp: 971-978
Xin Tong and Jill C. Pelling
DOI: 10.2174/18715206113139990119

Molecular Evidence of Cryptotanshinone for Treatment and Prevention of Human Cancer

Volume:13   Issue:7
Pp: 979-987
Wenxing Chen, Yin Lu, Guangying Chen and Shile Huang
DOI: 10.2174/18715206113139990115

Hitting the Golden TORget: Curcumin’s Effects on mTOR Signaling

Volume:13   Issue:7
Pp: 988-994
Christopher S. Beevers, Hongyu Zhou and Shile Huang
DOI: 10.2174/1871520611313070004

Inhibition of Akt/mTOR Signaling by the Dietary Flavonoid Fisetin

Volume:13   Issue:7
Pp: 995-1001
Deeba N. Syed, Vaqar M. Adhami, Mohammad Imran Khan and Hasan Mukhtar
DOI: 10.2174/18715206113139990129

Targeted Regulation of PI3K/Akt/mTOR/NF-κB Signaling by Indole Compounds and their Derivatives: Mechanistic Details and Biological Implications for Cancer Therapy

Volume:13   Issue:7
Pp: 1002-1013
Aamir Ahmad, Bernhard Biersack, Yiwei Li, Dejuan Kong, Bin Bao, Rainer Schobert, Subhash B. Padhye and Fazlul H. Sarkar
DOI: 10.2174/18715206113139990078

Deregulation of PI3K/Akt/mTOR Signaling Pathways by Isoflavones and its Implication in Cancer Treatment

Volume:13   Issue:7
Pp: 1014-1024
Aamir Ahmad, Bernhard Biersack, Yiwei Li, Dejuan Kong, Bin Bao, Rainer Schobert, Subhash B. Padhye and Fazlul H. Sarkar
DOI: 10.2174/18715206113139990117

Tocotrienols Target PI3K/Akt Signaling in Anti-Breast Cancer Therapy

Volume:13   Issue:7
Pp: 1039-1047
Paul W. Sylvester and Nehad M. Ayoub
DOI: 10.2174/18715206113139990116

Natural Products Targeting Autophagy via the PI3K/Akt/mTOR Pathway as Anticancer Agents

Volume:13   Issue:7
Pp: 1048-1056
Hui Sun, Zhaoye Wang and Juan Sebastian Yakisich
DOI: 10.2174/18715206113139990130

From Bacteria to Antineoplastic: Epothilones A Successful History

Volume:13   Issue:7
Pp: 1057-1068
Samuel Kaiser, Joseane John Muller, Pedro Eduardo Froehlich, Simone Cristina Baggio Gnoatto and Ana Maria Bergold
DOI: 10.2174/18715206113139990133

From Na+/K+-ATPase and Cardiac Glycosides to Cytotoxicity and Cancer Treatment

Volume:13   Issue:7
Pp: 1069-1087
Petr Babula, Michal Masarik, Vojtech Adam, Ivo Provaznik and Rene Kizek
DOI: 10.2174/18715206113139990304

Suppression of Oncoprotein Her-2 and DNA Damage after Treatment with Flavan-3- ol Vitis labrusca Extract

Volume:13   Issue:7
Pp: 1088-1095
Gustavo Scola, Claudia Cilene Fernandes Correia Laurino, Eveline Menin and Mirian Salvador
DOI: 10.2174/18715206113139990135

BIBR 1532 Increases Arsenic Trioxide-mediated Apoptosis in Acute Promyelocytic Leukemia Cells: Therapeutic Potential for APL

Volume:13   Issue:7
Pp: 1115-1125
Davood Bashash, Seyed H.Ghaffari, Farhad Zaker, Maryam Kazerani, Kebria Hezave, Saeed Hassani, Masomeh Rostami, Kamran Alimoghaddam and Ardeshir Ghavamzadeh
DOI: 10.2174/18715206113139990126

Oncogenic MicroRNA-27a is a Target for Genistein in Ovarian Cancer Cells

Volume:13   Issue:7
Pp: 1126-1132
Linlin Xu, Jingying Xiang, Jian Shen, Xi Zou, Sulan Zhai, Yongxiang Yin, Ping Li, Xuerong Wang and Qingmin Sun
DOI: 10.2174/18715206113139990006

Synthesis and Antiproliferative Effects of 5,6-Disubstituted Pyridazin-3(2H)-ones Designed as Conformationally Constrained Combretastatin A-4 Analogues

Volume:13   Issue:7
Pp: 1133-1140
Mohamed Elagawany, Martine Schmitt, Adel Ghiaty, A. Sh. El-Etrawy, Mohamed A. Ibrahim, Frederic Bihel, Aline Borba Sbardelotto, Claudia Pessoa, Tam Luong Nguyen, Ernest Hamel and Jean Jacques Bourguignon
DOI: 10.2174/1871520611313070018