Anti-Cancer Agents in Medicinal Chemistry

Quercetin Loaded Nanoparticles in Targeting Cancer: Recent Development

Volume: 19   Issue: 13
Pp: 1560-1576
Manjula Vinayak* and Akhilendra K. Maurya
DOI: 10.2174/1871520619666190705150214

Synthesis and Biological Evaluation of Novel 4,5,6,7-Tetrahydrobenzo[D]-Thiazol-2- Yl Derivatives Derived from Dimedone with Anti-Tumor, C-Met, Tyrosine Kinase and Pim-1 Inhibitions

Volume: 19   Issue: 12
Pp: 1438-1453
Rafat M. Mohareb*, Amr S. Abouzied and Nermeen S. Abbas
DOI: 10.2174/1871520619666190416102144

Novel Pyrazolo[3,4-d]pyrimidines as Potential Cytotoxic Agents: Design, Synthesis, Molecular Docking and CDK2 Inhibition

Volume: 19   Issue: 11
Pp: 1368-1381
Mai Maher , Asmaa E. Kassab*, Ashraf F. Zaher and Zeinab Mahmoud
DOI: 10.2174/1871520619666190417153350

Synthesis, Spectroscopic Properties, Crystal Structure And Biological Evaluation of New Platinum Complexes with 5-methyl-5-(2-thiomethyl)ethyl Hydantoin

Volume: 19   Issue: 10
Pp: 1243-1252
Adriana G. Bakalova*, Rossen T. Buyukliev, Rositsa P. Nikolova, Boris L. Shivachev, Rositsa A. Mihaylova and Spiro M. Konstantinov
DOI: 10.2174/1871520619666190214103345

Microsomal Prostaglandin E2 Synthase-1 as a New Macromolecular Drug Target in the Prevention of Inflammation and Cancer

Volume: 19   Issue: 10
Pp: 1205-1222
Bahadır Bülbül and İlkay Küçükgüzel*
DOI: 10.2174/1871520619666190227174137

Design, Synthesis, Anti-Proliferative Evaluation and Cell Cycle Analysis of Hybrid 2-Quinolones

Volume: 19   Issue: 9
Pp: 1132-1140
Heba A.E. Mohamed* and Hossa F. Al-Shareef
DOI: 10.2174/1871520619666190319142934

Synthesis of New Dihydroquinopimaric Acid Analogs with Nitrile Groups as Apoptosis-Inducing Anticancer Agents

Volume: 19   Issue: 9
Pp: 1172-1183
Elena V. Tretyakova*, Elena V. Salimova, Lyudmila V. Parfenova, Milyausha M. Yunusbaeva, Lilya U. Dzhemileva, Vladimir A. D’yakonov and Usein M. Dzhemilev
DOI: 10.2174/1871520619666190404100846

Unfolded Protein Response is Involved in Trans-Platinum (II) Complex-Induced Apoptosis in Prostate Cancer Cells via ROS Accumulation

Volume: 19   Issue: 9
Pp: 1184-1195
Didem Karakas, Buse Cevatemre, Arzu Y. Oral, Veysel T. Yilmaz and Engin Ulukaya*
DOI: 10.2174/1871520619666190409103334

2,4-Disubstituted Quinazoline Derivatives Act as Inducers of Tubulin Polymerization: Synthesis and Cytotoxicity

Volume: 19   Issue: 8
Pp: 1048-1057
Ebrahim S. Moghadam, Maryam H. Tehrani, René Csuk, Lucie Fischer, Mohammad Ali Faramarzi, Arezoo Rashidi, Iraj Javadi and Mohsen Amini*
DOI: 10.2174/1871520619666190314125254

Novel 1,3,4-Triaryl Pyrazoles: Synthesis, QSAR Studies and Cytotoxicity against Breast Cancer

Volume: 19   Issue: 7
Pp: 948-959
Magda M.F. Ismail, Amel M. Farrag and Marwa F. Harras*
DOI: 10.2174/1871520619666190207094610

Synthesis and In Vitro Evaluation of Tetrahydroquinoline Derivatives as Antiproliferative Compounds of Breast Cancer via Targeting the GPER

Volume: 19   Issue: 6
Pp: 760-771
Oscar J. Zacarías-Lara, David Méndez-Luna, Gustavo Martínez-Ruíz, José R. García-Sanchéz, Manuel J. Fragoso-Vázquez*, Martiniano Bello, Elvia Becerra-Martínez, Juan B. García-Vázquez and José Correa-Basurto*
DOI: 10.2174/1871520618666181119094144

Design, Synthesis and Antiproliferative Evaluation of Novel 1,2,4-Triazole/Schiff Base Hybrids with EGFR and B-RAF Inhibitory Activities

Volume: 19   Issue: 5
Pp: 697-706
Hany A.M. El-Sherief, Bahaa G.M. Youssif*, Ahmed H. Abdelazeem, Mohamed Abdel-Aziz and Hamdy M. Abdel-Rahman*
DOI: 10.2174/1871520619666181224115346

A New Synthetic Spiroketal: Studies on Antitumor Activity on Murine Melanoma Model In Vivo and Mechanism of Action In Vitro

Volume: 19   Issue: 4
Pp: 567-578
Maria P. Fuggetta*, Pietro Spanu*, Fausta Ulgheri, Francesco Deligia, Paola Carta, Alberto Mannu, Veronica Trotta, Rosanna De Cicco, Adriano Barra, Enrica Zona and Franco Morelli*
DOI: 10.2174/1871520619666190131141400

Novel Benzo[B]Furans with Anti-Microtubule Activity Upregulate Expression of Apoptotic Genes and Arrest Leukemia Cells in G2/M Phase

Volume: 19   Issue: 3
Pp: 375-388
Karolina Królewska-Golińska, Marcin J. Cieślak*, Milena Sobczak, Rafał Dolot, Ewa Radzikowska-Cieciura, Mariola Napiórkowska, Iwona Wybrańska and Barbara Nawrot
DOI: 10.2174/1871520619666181122123552

Isolation of a New Sesquiterpene Lactone From Vernonia Zeylanica (L) Less and its Anti-Proliferative Effects in Breast Cancer Cell Lines

Volume: 19   Issue: 3
Pp: 410-424
Anuka S. Mendis*, Ira Thabrew, Meran K. Ediriweera, Sameera R. Samarakoon, Kamani H. Tennekoon, Achyut Adhikari* and Egodage D. de Silva
DOI: 10.2174/1871520619666181128163359

Can Combined Therapy Benefit Immune Checkpoint Blockade Response in Hepatocellular Carcinoma?

Volume: 19   Issue: 2
Pp: 222-228
Fan Zhongqi, Sun Xiaodong, Chen Yuguo and Lv Guoyue*
DOI: 10.2174/1871520618666181114112431

Biological Activity and Physicochemical Properties of Dipeptidyl Nitrile Derivatives Against Pancreatic Ductal Adenocarcinoma Cells

Volume: 19   Issue: 1
Pp: 112-120
José C. Quilles Jr, Murillo D.L. Bernardi, Pedro H.J. Batista, Samelyn C.M. Silva, Camila M.R. Rocha, Carlos A. Montanari and Andrei Leitão*
DOI: 10.2174/1871520618666181029141649

Crocetin and Crocin from Saffron in Cancer Chemotherapy and Chemoprevention

Volume: 19   Issue: 1
Pp: 38-47
Alessandro Colapietro, Andrea Mancini, Anna Maria D'Alessandro and Claudio Festuccia*
DOI: 10.2174/1871520619666181231112453

Biomarkers in Non-Small Cell Lung Cancer: Perspectives of Individualized Targeted Therapy

Volume: 18   Issue: 15
Pp: 2070-2077
Mateus N. Aoki*, Marla K. Amarante, Carlos E.C. de Oliveira and Maria A.E. Watanabe
DOI: 10.2174/1871520618666180827102101

MMP7 Induces T-DM1 Resistance and Leads to the Poor Prognosis of Gastric Adenocarcinoma via a DKK1-Dependent Manner

Volume: 18   Issue: 14
Pp: 2010-2016
Hua Li, Xin Xu, Yang Liu, Shunle Li, Di Zhang, Xiaofen Meng, Le Lu and Yiming Li*
DOI: 10.2174/1871520619666181203111329

Synthesis, 17α-hydroxylase-C17,20-lyase Inhibitory and 5AR Reductase Activity of Novel Pregnenolone Derivatives

Volume: 18   Issue: 13
Pp: 1919-1926
Abid H. Banday*, Shameem A. Shameem, Javid A. Banday and Bashir A. Ganaie
DOI: 10.2174/1871520618666180426100942

Association of Phytol with Toxic and Cytotoxic Activities in an Antitumoral Perspective: A Meta-Analysis and Systemic Review

Volume: 18   Issue: 13
Pp: 1828-1837
Marcus V.O.B. Alencar, Muhammad T. Islam*, Eunus S. Ali, José V.O. Santos, Márcia F.C.J. Paz, João M.C. Sousa, Sandra M.M.M. Dantas, Siddhartha K. Mishra* and Ana A.C.M. Cavalcante
DOI: 10.2174/1871520618666180821113830

One-Pot Synthesis of Triazolo-Heterolignans: Biological Evaluation and Molecular Docking Studies as Tubulin Inhibitors

Volume: 18   Issue: 12
Pp: 1702-1710
Chada Raji Reddy*, Muppidi Subbarao, Jonnalagadda Vijaykumar, Surender Singh Jadav, Nilesh Sasane, Reddi Rani Valleti, Bhukya Supriya and Ramesh Ummanni*
DOI: 10.2174/1871520618666180718104647

Selection of a GPER1 Ligand via Ligand-based Virtual Screening Coupled to Molecular Dynamics Simulations and Its Anti-proliferative Effects on Breast Cancer Cells

Volume: 18   Issue: 11
Pp: 1629-1638
Alberto Martínez-Muñoz, Berenice Prestegui-Martel, David Méndez-Luna, Manuel J. Fragoso-Vázquez*, José Rubén García-Sánchez, Martiniano Bello, Marlet Martínez-Archundia, Alma Chávez-Blanco, Alfonso Dueñas-González, Irene Mendoza-Lujambio, José Trujillo-Ferrara and José Correa-Basurto*
DOI: 10.2174/1871520618666180510121431

Parallel Solid-Phase Synthesis using a New Diethylsilylacetylenic Linker and Leading to Mestranol Derivatives with Potent Antiproliferative Activities on Multiple Cancer Cell Lines

Volume: 18   Issue: 10
Pp: 1469-1481
Raphaël Dutour, René Maltais, Martin Perreault, Jenny Roy and Donald Poirier*
DOI: 10.2174/1871520618666180307130158

⁶⁸Ga-labeled HBED-CC Variant of uPAR Targeting Peptide AE105 Compared with ⁶⁸Ga-NODAGA-AE105

Volume: 18   Issue: 9
Pp: 1289-1294
Kusum Vats, Rohit Sharma, Haladhar D. Sarma, Drishty Satpati* and Ashutosh Dash
DOI: 10.2174/1871520618666180316152618

Potential Pharmacological Inhibitors of Pim Kinase Under Clinical Trials

Volume: 18   Issue: 8
Pp: 1100-1114
Gomathi P. Jeyapal, Moola J.N. Chandrasekar*, Rajendiran Krishnasamy, Jubie Selvaraj, Manal Mohammad and Moola J. Nanjan
DOI: 10.2174/1871520618666180131113519

Design, Synthesis, and Biological Evaluation of New Azole Derivatives as Potent Aromatase Inhibitors with Potential Effects against Breast Cancer

Volume: 18   Issue: 7
Pp: 1016-1024
Fatemeh Kalalinia, Mohammad Jouya, Alireza K. Komachali, Seyed M. Aboutourabzadeh, Gholamreza Karimi*, Javad Behravan, Khalil Abnous, Leila Etemad, Hossein Kamali and Farzin Hadizadeh*
DOI: 10.2174/1871520618666180116105858

Polyphyllin I Induces Cell Cycle Arrest and Cell Apoptosis in Human Retinoblastoma Y-79 Cells through Targeting p53

Volume: 18   Issue: 6
Pp: 875-881
Xue Zhu, Ke Wang*, Kai Zhang, Yi Pan, Fanfan Zhou and Ling Zhu
DOI: 10.2174/1871520618666180108095148

Antitumor Potential of Marine Natural Products: A Mechanistic Investigation

Volume: 18   Issue: 5
Pp: 702-718
Liping Hu, Jie Ying, Miaomiao Zhang, Xiaoyan Qiu and Yu Lu*
DOI: 10.2174/1871520617666170918142811

Synthesis and Evaluation of 2-Naphthaleno trans-Stilbenes and Cyanostilbenes as Anticancer Agents

Volume: 18   Issue: 4
Pp: 556-564
Nikhil R. Madadi, Narsimha R. Penthala, Amit Ketkar, Robert L. Eoff, Vicenta Trujullo-Alonso, Monica L. Guzman and Peter A. Crooks*
DOI: 10.2174/1871521409666170412115703

ECPIRM, a Potential Therapeutic Agent for Cutaneous T-Cell Lymphoma, Inhibits Cell Proliferation and Promotes Apoptosis via a JAK/STAT Pathway

Volume: 18   Issue: 3
Pp: 401-411
Hua Yang, Pengcheng Ma*, Yuping Cao, Mengli Zhang, Lingjun Li, Jun Wei, Lei Tao and Kun Qian
DOI: 10.2174/1871520617666170327115657

Novel Findings of Anti-cancer Property of Propofol

Volume: 18   Issue: 2
Pp: 156-165
Jiaqiang Wang, Chien-shan Cheng, Yan Lu, Xiaowei Ding, Minmin Zhu, Changhong Miao* and Jiawei Chen*
DOI: 10.2174/1871520617666170912120327

Evaluation of the in vitro Chemosensitivity and Correlation with Clinical Outcomes in Lung Cancer using the ATP-TCA promotion: free to download

Volume: 18   Issue: 1
Pp: 139-145
Zhiyao Chen, Shichao Zhang, Sheng Ma, Chang Li, Chun Xu, Yinfang Shen, Jun Zhao* and Liyan Miao*
DOI: 10.2174/1871520617666170419123713

4-aryl/heteroaryl-4H-fused Pyrans as Anti-proliferative Agents: Design, Synthesis and Biological Evaluation promotion: free to download

Volume: 18   Issue: 1
Pp: 57-73
Dinesh Kumar*, Gurpreet Singh, Pooja Sharma, Arem Qayum, Girish Mahajan, M.J. Mintoo, Shashank Kumar Singh, Dilip Manikrao Mondhe, P.M.S. Bedi, Subheet K. Jain and Girish Kumar Gupta
DOI: 10.2174/1871520617666170918143911

Tetrazole Derivatives as Promising Anticancer Agents

Volume: 17   Issue: 14
Pp: 1856-1868
Elena A. Popova*, Aleksandra V. Protas and Rostislav E. Trifonov
DOI: 10.2174/1871520617666170327143148

The Oxime Derivatives of 1-R-1H-Naphtho[2,3-d][1,2,3]triazole-4,9-dione 2-oxides: Synthesis and Properties

Volume: 17   Issue: 13
Pp: 1814-1823
Leonid M. Gornostaev*, Vladimir B. Tsvetkov, Alina A. Markova, Tatyana I. Lavrikova, Yulia G. Khalyavina, Anastasia S. Kuznetsova, Dmitry N. Kaluzhny, Alexei V. Shunayev, Maria V. Tsvetkova, Valeria A. Glazunova, Vladimir V. Chernyshev and Alexander A. Shtil*
DOI: 10.2174/1871520617666170327112216

Synthesis and Evaluation of Antioxidant and Cytotoxicity of the N-Mannich Base of Berberine Bearing Benzothiazole Moieties

Volume: 17   Issue: 12
Pp: 1652-1660
Bhupendra M. Mistry, Han-Seung Shin, Young-Soo Keum, Muthuraman Pandurangan, Doo Hwan Kim, So Hyun Moon, Avinash A. Kadam, Surendra K. Shinde and Rahul V. Patel*
DOI: 10.2174/1871520617666170710180549

The Cross-talk between Tristetraprolin and Cytokines in Cancer

Volume: 17   Issue: 11
Pp: 1477-1486
Jian Guo, Hao Wang, Shiyi Jiang, Jiazeng Xia * and Shimao Jin *
DOI: 10.2174/1871520617666170327155124

Inhibition of TGF-β Signaling in Tumor Cells by Small Molecule Src Family Kinase Inhibitors

Volume: 17   Issue: 10
Pp: 1351-1356
Tobias Bartscht, Benjamin Rosien, Dirk Rades, Roland Kaufmann, Harald Biersack, Hendrik Lehnerta and Hendrik Ungefroren*
DOI: 10.2174/1871520617666170103094946

Novel Thiourea Derivatives Bearing Sulfonamide Moiety as Anticancer Agents Through COX-2 Inhibition

Volume: 17   Issue: 10
Pp: 1411-1425
Mostafa M. Ghorab*, Mohamed S.A. El-Gaby, Mansour S. Alsaid, Yaseen A.M.M. Elshaier, Aiten M. Soliman , Fardous F. El-Senduny , Farid A. Badria and Abdelrahman Y.A. Sherif
DOI: 10.2174/1871520617666170327153735

Cytokine Status of Serum in Ovarian Cancer Patients with Different Tumor Neoadjuvant Chemotherapy Response

Volume: 17   Issue: 9
Pp: 1251-1255
Inna I. Antoneeva, Tatyana V. Abakumova, Dinara R. Dolgova, Tatyana P. Gening*, Sabina S. Pirmamedova, Dinara F. Myasnikova and Snezhanna O. Gening
DOI: 10.2174/1871520617666170103100350

Ring A-modified Derivatives from the Natural Triterpene 3-O-acetyl-11-keto-β-Boswellic Acid and their Cytotoxic Activity

Volume: 17   Issue: 8
Pp: 1153-1167
Tao Li, Peihong Fan, Yaqing Ye, Qian Luo and Hongxiang Lou*
DOI: 10.2174/1871520616666161207144031

Polo-like Kinase 1-targeting Chitosan Nanoparticles Suppress the Progression of Hepatocellular Carcinoma

Volume: 17   Issue: 7
Pp: 948-954
Dongzhi Wang, Renan Chang, Gang Wang, Baoying Hu, Yong Qiang and Zhong Chen*
DOI: 10.2174/1871520616666160926111911

2-(ω-Carboxyethyl)pyrrole Antibody as a New Inhibitor of Tumor Angiogenesis and Growth

Volume: 17   Issue: 6
Pp: 813-820
Chunying Wu, Xizhen Wang, Nicholas Tomko, Junqing Zhu, William R. Wang, Jinle Zhu, Bin Wangf, Yanming Wang* and Robert G. Salomon*
DOI: 10.2174/1871520616666160923093959

The Effects of 1,3,5-trisubstituted Indole Derivatives on Cell Growth, Apoptosis and MMP-2/9 mRNA Expression of MCF-7 Human Breast Cancer Cells

Volume: 17   Issue: 5
Pp: 762-767
Filiz Bakar*, Zuhal Kilic-Kurt, Mehmet Gokhan Caglayan and Sureyya Olgen
DOI: 10.2174/1871520616666160802115737

Y-shaped Folic Acid-Conjugated PEG-PCL Copolymeric Micelles for Delivery of Curcumin

Volume: 17   Issue: 4
Pp: 599-607
Runliang Feng, Wenxia Zhu, Wei Chu, Fangfang Teng, Ning Meng, Peizong Deng and Zhimei Song
DOI: 10.2174/1871520616666160815124014

Design and Synthesis of Coumarin Derivatives as Novel PI3K Inhibitors

Volume: 17   Issue: 3
Pp: 395-403
Chen-Chen Ma and Zhao-Peng Liu
DOI: 10.2174/1871520616666160223120207

Differential Cytotoxicity, Cellular Uptake, Apoptosis and Inhibition of BRCA1 Expression of BRCA1-Defective and Sporadic Breast Cancer Cells Induced by an Anticancer Ruthenium(II)-Arene Compound, RAPTA-EA1

Volume: 17   Issue: 2
Pp: 212-220
Adisorn Ratanaphan, Tidarat Nhukeaw, Khwanjira Hongthong and Paul J. Dyson
DOI: 10.2174/1871520616666160404110953

Design, Synthesis and Evaluation of 5-pyridin-4-yl-2-thioxo-[1,3,4]oxadiazol-3-yl Derivatives as Anti-angiogenic Agents Targeting VEGFR-2

Volume: 17   Issue: 1
Pp: 67-74
Umesh Bhanushali, Samidha Kalekar-Joshi, Renuka Kulkarni-Munshi, Swapna Yellanki, Raghavender Medishetty, Pushkar Kulkarni and Ramaa Subramanian Chelakara
DOI: 10.2174/1871520615666160504094222

Brain-metastatic Breast Cancer: Clinical Considerations and Pharmacological Approaches

Volume: 16   Issue: 12
Pp: 1523-1528
Ana C. Andrade, Daniel S. Ferruzzi and Carolina Panis
DOI: 10.2174/1871520616666160404112508

Molecular Mechanisms of Anti-cancer Activities of β-elemene: Targeting Hallmarks of Cancer

Volume: 16   Issue: 11
Pp: 1426-1434
Shiyu Jiang, Chunhua Ling, Wei Li, Hongxin Jiang, Qiaoming Zhi and Min Jiang
DOI: 10.2174/1871520616666160211123424

Flavonoids with Therapeutic Potential in Prostate Cancer

Volume: 16   Issue: 10
Pp: 1205-1229
Bao Vue, Sheng Zhang and Qiao-Hong Chen
DOI: 10.2174/1871520615666151008122622

Evolving Role of Radiopharmaceuticals in Hepatocellular Carcinoma Treatment

Volume: 16   Issue: 9
Pp: 1155-1165
Lu Wu, Feng Shen, Yong Xia and Ye-Fa Yang
DOI: 10.2174/1871520616666160310143148

Synthesis of Combretastatin A-4 Analogs and their Biological Activities

Volume: 16   Issue: 8
Pp: 942-960
Agnieszka Siebert, Monika Gensicka, Grzegorz Cholewinski and Krystyna Dzierzbicka
DOI: 10.2174/1871520616666160204111832

α(N)-Heterocyclic Thiosemicarbazones: Iron Chelators that are Promising for Revival of Gallium in Cancer Chemotherapy

Volume: 16   Issue: 8
Pp: 973-991
Shuhong Cao, Xiahui Chen, Ligen Chen and Jingwen Chen
DOI: 10.2174/1871520616666160310142012

A Review on Novel Breast Cancer Therapies: Photodynamic Therapy and Plant Derived Agent Induced Cell Death Mechanisms

Volume: 16   Issue: 7
Pp: 793-801
Blassan Plackal Adimuriyil George and Heidi Abrahamse
DOI: 10.2174/1871520615666151026094028

Blood-Brain Barrier and Breast Cancer Resistance Protein: A Limit to the Therapy of CNS Tumors and Neurodegenerative Diseases open access plus

Volume: 16   Issue: 7
Pp: 810-815
Anna Lisa Iorio, Martina da Ros, Ornella Fantappiè, Maurizio Lucchesi, Ludovica Facchini, Alessia Stival, Sabrina Becciani, Milena Guidi, Claudio Favre, Maurizio de Martino, Lorenzo Genitori and Iacopo Sardi
DOI: 10.2174/1871520616666151120121928

Tannic Acid Inhibits Proliferation, Migration, Invasion of Prostate Cancer and Modulates Drug Metabolizing and Antioxidant Enzymes

Volume: 16   Issue: 6
Pp: 781-789
Serdar Karakurt and Orhan Adali
DOI: 10.2174/1871520616666151111115809

Expeditious Entry to Functionalized Pseudo-peptidic Organoselenide Redox Modulators via Sequential Ugi/SN Methodology

Volume: 16   Issue: 5
Pp: 621-632
Saad Shaaban, Amr Negm, Mohamed A. Sobh and Ludger A. Wessjohann
DOI: 10.2174/1871520615666150916092035

Recent Developments on 1,2,4-Triazole Nucleus in Anticancer Compounds: A Review

Volume: 16   Issue: 4
Pp: 465-489
Ramandeep Kaur, Ashish Ranjan Dwivedi, Bhupinder Kumar and Vinod Kumar
DOI: 10.2174/1871520615666150819121106

Paclitaxel Loaded Nanoliposomes in Thermosensitive Hydrogel: A Dual Approach for Sustained and Localized Delivery

Volume: 16   Issue: 3
Pp: 365-376
Mohit Mahajan, Puneet Utreja and Subheet Kumar Jain
DOI: 10.2174/1871520615666150807103910

The Induction and Repair of DNA Interstrand Crosslinks and Implications in Cancer Chemotherapy

Volume: 16   Issue: 2
Pp: 221-246
Sun Guohui, Zhao Lijiao and Zhong Rugang
DOI: 10.2174/1871520615666150824160421

CXCR4 and Glioblastoma promotion: free to download

Volume: 16   Issue: 1
Pp: 59-74
Peter J. Richardson
DOI: 10.2174/1871520615666150824153032

Role of Rap2 and its Downstream Effectors in Tumorigenesis

Volume: 15   Issue: 10
Pp: 1269-1276
Hui Huang, Jiehui Di, Debao Qu, Zhen Gao, Yanping Zhang and Junnian Zheng
DOI: 10.2174/1871520615666150518092840

Recent Advances in Phenanthroindolizidine and Phenanthroquinolizidine Derivatives with Anticancer Activities

Volume: 15   Issue: 9
Pp: 1080-1091
Maria de Fatima Pereira, Christophe Rochais and Patrick Dallemagne
DOI: 10.2174/1871520615666150520143600

Anticancer Agents Derived from Natural Cinnamic Acids

Volume: 15   Issue: 8
Pp: 980-987
Ping Su, Yaling Shi, Jinfeng Wang, Xiuxiu Shen and Jie Zhang
DOI: 10.2174/1871520615666150130111120

Is Notch Signaling a Specific Target in Hepatocellular Carcinoma?

Volume: 15   Issue: 7
Pp: 809-815
Lichun Sun, Guangchun Sun, Yan Yu and David H. Coy
DOI: 10.2174/1871520615666150202102809

Molecular Mechanism Behind the Synergistic Activity of Diphenylmethyl Selenocyanate and Cisplatin Against Murine Tumor Model

Volume: 15   Issue: 4
Pp: 501-510
Pramita Chakraborty, Somnath Singha Roy and Sudin Bhattacharya
DOI: 10.2174/1871520615666150113123401