Anti-Cancer Agents in Medicinal Chemistry

(Formerly Current Medicinal Chemistry - Anti-Cancer Agents)

This journal supports open access

Editor-in-Chief:

Michelle Prudhomme
Institut de Chimie de Clermont-Ferrand
ICCF-CNRS UMR 6296
Université Clermont Auvergne
Clermont-Ferrand
France

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Editor's Choice

Tetrazole Derivatives as Promising Anticancer Agents

Volume: 17   Issue: 14
Pp: 1856-1868
Elena A. Popova*, Aleksandra V. Protas and Rostislav E. Trifonov
DOI: 10.2174/1871520617666170327143148

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The Oxime Derivatives of 1-R-1H-Naphtho[2,3-d][1,2,3]triazole-4,9-dione 2-oxides: Synthesis and Properties

Volume: 17   Issue: 13
Pp: 1814-1823
Leonid M. Gornostaev*, Vladimir B. Tsvetkov, Alina A. Markova, Tatyana I. Lavrikova, Yulia G. Khalyavina, Anastasia S. Kuznetsova, Dmitry N. Kaluzhny, Alexei V. Shunayev, Maria V. Tsvetkova, Valeria A. Glazunova, Vladimir V. Chernyshev and Alexander A. Shtil*
DOI: 10.2174/1871520617666170327112216

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Synthesis and Evaluation of Antioxidant and Cytotoxicity of the N-Mannich Base of Berberine Bearing Benzothiazole Moieties

Volume: 17   Issue: 12
Pp: 1652-1660
Bhupendra M. Mistry, Han-Seung Shin, Young-Soo Keum, Muthuraman Pandurangan, Doo Hwan Kim, So Hyun Moon, Avinash A. Kadam, Surendra K. Shinde and Rahul V. Patel*
DOI: 10.2174/1871520617666170710180549

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The Cross-talk between Tristetraprolin and Cytokines in Cancer

Volume: 17   Issue: 11
Pp: 1477-1486
Jian Guo, Hao Wang, Shiyi Jiang, Jiazeng Xia * and Shimao Jin *
DOI: 10.2174/1871520617666170327155124

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Inhibition of TGF-β Signaling in Tumor Cells by Small Molecule Src Family Kinase Inhibitors

Volume: 17   Issue: 10
Pp: 1351-1356
Tobias Bartscht, Benjamin Rosien, Dirk Rades, Roland Kaufmann, Harald Biersack, Hendrik Lehnerta and Hendrik Ungefroren*
DOI: 10.2174/1871520617666170103094946

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Novel Thiourea Derivatives Bearing Sulfonamide Moiety as Anticancer Agents Through COX-2 Inhibition

Volume: 17   Issue: 10
Pp: 1411-1425
Mostafa M. Ghorab*, Mohamed S.A. El-Gaby, Mansour S. Alsaid, Yaseen A.M.M. Elshaier, Aiten M. Soliman , Fardous F. El-Senduny , Farid A. Badria and Abdelrahman Y.A. Sherif
DOI: 10.2174/1871520617666170327153735

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Cytokine Status of Serum in Ovarian Cancer Patients with Different Tumor Neoadjuvant Chemotherapy Response

Volume: 17   Issue: 9
Pp: 1251-1255
Inna I. Antoneeva, Tatyana V. Abakumova, Dinara R. Dolgova, Tatyana P. Gening*, Sabina S. Pirmamedova, Dinara F. Myasnikova and Snezhanna O. Gening
DOI: 10.2174/1871520617666170103100350

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Polo-like Kinase 1-targeting Chitosan Nanoparticles Suppress the Progression of Hepatocellular Carcinoma

Volume: 17   Issue: 7
Pp: 948-954
Dongzhi Wang, Renan Chang, Gang Wang, Baoying Hu, Yong Qiang and Zhong Chen*
DOI: 10.2174/1871520616666160926111911

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2-(ω-Carboxyethyl)pyrrole Antibody as a New Inhibitor of Tumor Angiogenesis and Growth

Volume: 17   Issue: 6
Pp: 813-820
Chunying Wu, Xizhen Wang, Nicholas Tomko, Junqing Zhu, William R. Wang, Jinle Zhu, Bin Wangf, Yanming Wang* and Robert G. Salomon*
DOI: 10.2174/1871520616666160923093959

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Design, Synthesis and Evaluation of 5-pyridin-4-yl-2-thioxo-[1,3,4]oxadiazol-3-yl Derivatives as Anti-angiogenic Agents Targeting VEGFR-2

Volume: 17   Issue: 1
Pp: 67-74
Umesh Bhanushali, Samidha Kalekar-Joshi, Renuka Kulkarni-Munshi, Swapna Yellanki, Raghavender Medishetty, Pushkar Kulkarni and Ramaa Subramanian Chelakara
DOI: 10.2174/1871520615666160504094222

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Molecular Mechanisms of Anti-cancer Activities of β-elemene: Targeting Hallmarks of Cancer

Volume: 16   Issue: 11
Pp: 1426-1434
Shiyu Jiang, Chunhua Ling, Wei Li, Hongxin Jiang, Qiaoming Zhi and Min Jiang
DOI: 10.2174/1871520616666160211123424

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Flavonoids with Therapeutic Potential in Prostate Cancer

Volume: 16   Issue: 10
Pp: 1205-1229
Bao Vue, Sheng Zhang and Qiao-Hong Chen
DOI: 10.2174/1871520615666151008122622

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Synthesis of Combretastatin A-4 Analogs and their Biological Activities

Volume: 16   Issue: 8
Pp: 942-960
Agnieszka Siebert, Monika Gensicka, Grzegorz Cholewinski and Krystyna Dzierzbicka
DOI: 10.2174/1871520616666160204111832

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Blood-Brain Barrier and Breast Cancer Resistance Protein: A Limit to the Therapy of CNS Tumors and Neurodegenerative Diseases open access plus

Volume: 16   Issue: 7
Pp: 810-815
Anna Lisa Iorio, Martina da Ros, Ornella Fantappiè, Maurizio Lucchesi, Ludovica Facchini, Alessia Stival, Sabrina Becciani, Milena Guidi, Claudio Favre, Maurizio de Martino, Lorenzo Genitori and Iacopo Sardi
DOI: 10.2174/1871520616666151120121928

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CXCR4 and Glioblastoma promotion: free to download

Volume: 16   Issue: 1
Pp: 59-74
Peter J. Richardson
DOI: 10.2174/1871520615666150824153032

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Role of Rap2 and its Downstream Effectors in Tumorigenesis

Volume: 15   Issue: 10
Pp: 1269-1276
Hui Huang, Jiehui Di, Debao Qu, Zhen Gao, Yanping Zhang and Junnian Zheng
DOI: 10.2174/1871520615666150518092840

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Anticancer Agents Derived from Natural Cinnamic Acids

Volume: 15   Issue: 8
Pp: 980-987
Ping Su, Yaling Shi, Jinfeng Wang, Xiuxiu Shen and Jie Zhang
DOI: 10.2174/1871520615666150130111120

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Is Notch Signaling a Specific Target in Hepatocellular Carcinoma?

Volume: 15   Issue: 7
Pp: 809-815
Lichun Sun, Guangchun Sun, Yan Yu and David H. Coy
DOI: 10.2174/1871520615666150202102809

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Immune Checkpoint Inhibitors for Non-small-cell Lung Cancer: Does that Represent a ‘New Frontier’?

Volume: 15   Issue: 3
Pp: 307-313
Sara Pilotto, Stefania Kinspergher, Umberto Peretti, Anna Calio, Luisa Carbognin, Roberto Ferrara, Matteo Brunelli, Marco Chilosi, Giampaolo Tortora and Emilio Bria
DOI: 10.2174/1871520614666141110170259

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Berberine Interfered with Breast Cancer Cells Metabolism, Balancing Energy Homeostasis promotion: free to download

Volume: 15   Issue: 1
Pp: 66-78
Wen Tan, Ning Li, Rui Tan, Zhangfeng Zhong, Zhanwei Suo, Xian Yang, Yitao Wang and Xiaodong Hu
DOI: 10.2174/1871520614666140910120518

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Pro-Oxidative Action of Polyphenols as Action Mechanism for their Pro-Apoptotic Activity

Volume: 14   Issue: 10
Pp: 1363-1375
Raffaella Marina Lecci, Antonio Logrieco and Antonella Leone
DOI: 10.2174/1871520614666140922121014

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New Potent and Selective Inhibitor of Pim-1/3 Protein Kinases Sensitizes Human Colon Carcinoma Cells to Doxorubicin

Volume: 14   Issue: 9
Pp: 1228-1236
Pascale Moreau, Lyubov G. Dezhenkova, Fabrice Anizon, Lionel Nauton, Vincent Thery, Shuguang Liang, Dmitry N. Kaluzhny and Alexander A. Shtil
DOI: 10.2174/1871520614666140825124456

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