Abstract
Cancer is a complex multifactorial disease requiring combinations of several therapeutic modalities to treat it effectively. Despite advances in the field of prevention and treatment of cancer, morbidity and mortality remain high, especially for tumors that cannot be completely removed, as well as for those that are highly recurrent or highly metastatic. Surgery, radiotherapy and chemotherapy, alone or in combination, are currently the prevalent treatment modalities. Yet, in order to treat metastases more effectively, the immune response must be recruited. In this review, we will focus on recent patents in the field of cancer that have concentrated on combining chemotherapy or radiotherapy strategies with immunotherapy, in order to eradicate the primary tumor as well as its metastases.
Keywords: Cancer, radiotherapy, chemotherapy, immunotherapy, combination therapy, synergy
Recent Patents on Anti-Cancer Drug Discovery
Title: Innovative Cancer Treatments that Augment Radiotherapy or Chemotherapy by the Use of Immunotherapy or Gene Therapy
Volume: 1 Issue: 2
Author(s): Rudolf Lucas and Yona Keisari
Affiliation:
Keywords: Cancer, radiotherapy, chemotherapy, immunotherapy, combination therapy, synergy
Abstract: Cancer is a complex multifactorial disease requiring combinations of several therapeutic modalities to treat it effectively. Despite advances in the field of prevention and treatment of cancer, morbidity and mortality remain high, especially for tumors that cannot be completely removed, as well as for those that are highly recurrent or highly metastatic. Surgery, radiotherapy and chemotherapy, alone or in combination, are currently the prevalent treatment modalities. Yet, in order to treat metastases more effectively, the immune response must be recruited. In this review, we will focus on recent patents in the field of cancer that have concentrated on combining chemotherapy or radiotherapy strategies with immunotherapy, in order to eradicate the primary tumor as well as its metastases.
Export Options
About this article
Cite this article as:
Lucas Rudolf and Keisari Yona, Innovative Cancer Treatments that Augment Radiotherapy or Chemotherapy by the Use of Immunotherapy or Gene Therapy, Recent Patents on Anti-Cancer Drug Discovery 2006; 1 (2) . https://dx.doi.org/10.2174/157489206777442214
DOI https://dx.doi.org/10.2174/157489206777442214 |
Print ISSN 1574-8928 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3970 |
Call for Papers in Thematic Issues
Novel anti-cancer drugs in photoimmunotherapy management: from bench to translational research
In recent years, traditional cancer treatments, such as surgery, chemotherapy, and radiation treatment, etc., may damage the pathological tissue and normal cells. The ideal tumor treatment should be noninvasive, eliminating the primary tumor, making the body produce systemic tumor-specific immunity, eliminating metastases, and having less /no side effects. Recent Patents ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Protective Effects of Curcumin against Lipopolysaccharide-Induced Toxicity
Current Medicinal Chemistry Nitrergic Modulation of Gastrointestinal Function During Early Endotoxemia
Current Pharmaceutical Design Cerebrovascular Profile Assessment in Parkinson's Disease Patients
CNS & Neurological Disorders - Drug Targets New Strategies for Necrotizing Enterocolitis Diagnosis and Prevention in Newborns
Current Pediatric Reviews Renin Inhibition as a New Strategy to Combat Cardiovascular Disease
Current Hypertension Reviews The Role of Growth Factors in the Prevention and Treatment of Chemotherapy-Induced Peripheral Neurotoxicity
Current Drug Safety Update in Glaucoma Medicinal Chemistry: Emerging Evidence for the Importance of Melatonin Analogues
Current Medicinal Chemistry NTproBNP: An Important Biomarker in Cardiac Diseases
Current Topics in Medicinal Chemistry Dangerous Liaisons between Beta-Amyloid and Cholinergic Neurotransmission
Current Pharmaceutical Design Acute Fulminant Hepatatis in Kidney Transplant Recipient After Repeated Sevoflurane Anesthesia - A Case Report and Literature Review
Current Drug Safety Putative Role for Apelin in Pressure/Volume Homeostasis and Cardiovascular Disease
Cardiovascular & Hematological Agents in Medicinal Chemistry Engineered Nanoparticles for Improved Vasoactive Intestinal Peptide (VIP) Biomedical Applications
Recent Patents on Nanomedicine Bone Disease in Diabetes
Current Diabetes Reviews Receptor Binding Ligands to Image Infection
Current Pharmaceutical Design Regulation of Angiogenesis by the Kallikrein-Kinin System
Current Pharmaceutical Design A Systematic Approach to Hypertensive Urgencies and Emergencies
Current Hypertension Reviews Chemotherapy and Cardiotoxicity in Hematologic Malignancies
Current Cancer Drug Targets Neuroprotection for Ischemic Injury in the Immature Brain
Current Pediatric Reviews Ligands and Therapeutic Perspectives of Adenosine A2A Receptors
Current Pharmaceutical Design Drug-Induced Hypokalaemia
Current Drug Safety