Abstract
Imiquimod is a synthetic imidazoquinoline heterocyclic amine of 240.3 Da (C14H16N4). Imiquimod is a cytokine inducer and a modifier of the innate immune response, as well as acquired antiviral and antitumor immune responses. Imiquimod 5% cream has proven to be an effective treatment for external genital warts, superficial basal cell carcinoma, and actinic keratosis.
Keywords: Imiquimod, imidazoquinolone, immune response modifier, toll-like receptor, skin infection, skin cancer
Mini-Reviews in Medicinal Chemistry
Title: Topical Imiquimod: Mechanism of Action and Clinical Applications
Volume: 6 Issue: 5
Author(s): David Vidal
Affiliation:
Keywords: Imiquimod, imidazoquinolone, immune response modifier, toll-like receptor, skin infection, skin cancer
Abstract: Imiquimod is a synthetic imidazoquinoline heterocyclic amine of 240.3 Da (C14H16N4). Imiquimod is a cytokine inducer and a modifier of the innate immune response, as well as acquired antiviral and antitumor immune responses. Imiquimod 5% cream has proven to be an effective treatment for external genital warts, superficial basal cell carcinoma, and actinic keratosis.
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Cite this article as:
Vidal David, Topical Imiquimod: Mechanism of Action and Clinical Applications, Mini-Reviews in Medicinal Chemistry 2006; 6 (5) . https://dx.doi.org/10.2174/138955706776876131
DOI https://dx.doi.org/10.2174/138955706776876131 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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