Synthesis and Evaluation of Hypolipidemic Properties of some Novel Derivatives of Thieno Oxazine and 5-Hydroxyindole-2-Carboxylic Acid

Title: Synthesis and Evaluation of Hypolipidemic Properties of some Novel Derivatives of Thieno Oxazine and 5-Hydroxyindole-2-Carboxylic Acid

Volume: 3 Issue: 3

Author(s): Sankar Mohan, K. A. Reddy, Javed Iqbal, Debnath Bhuniya and Saibal K. Das

Affiliation:

Keywords: Synthesis, thieno oxazine, indole carboxylic acid, hypolipidemic properties, triglyceride

Abstract: Two series of molecules were synthesized with carboxamidomethyl linker utilizing thieno oxazine and 5-Hydroxyindole-2-carboxylic acid. In vivo studies of these molecules indicated that molecules from each series, 4h and 5b, are very potent triglyceride lowering agents.

Cite this article as:

Mohan Sankar, Reddy A. K., Iqbal Javed, Bhuniya Debnath and Das K. Saibal, Synthesis and Evaluation of Hypolipidemic Properties of some Novel Derivatives of Thieno Oxazine and 5-Hydroxyindole-2-Carboxylic Acid, Letters in Drug Design & Discovery 2006; 3 (3) . https://dx.doi.org/10.2174/157018006776287014