Regulation of MMP/TIMP Balance as Therapeutic Target in Pulmonary Diseases

Title: Regulation of MMP/TIMP Balance as Therapeutic Target in Pulmonary Diseases

Volume: 3 Issue: 3

Author(s): Corinne A.E. Martin-Chouly, Stephanie Guillot, Stephane Jouneau, Sylvie Caulet-Maugendre, Laurent Vernhet, Vincent Lagente and Philippe Delaval

Affiliation:

Keywords: Pulmonary diseases, MMP, TIMP, EMMPRIN, regulation

Abstract: Matrix metalloproteinases (MMPs) are a family of zinc endopeptidases, regulated by endogenous tissue inhibitors (TIMPs) and inducer (EMMPRIN). The demonstration of a functional role of MMPs in pulmonary diseases raises the possibility of therapeutic intervention targeting MMP/TIMP balance to prevent pathological processes.

Cite this article as:

Martin-Chouly A.E. Corinne, Guillot Stephanie, Jouneau Stephane, Caulet-Maugendre Sylvie, Vernhet Laurent, Lagente Vincent and Delaval Philippe, Regulation of MMP/TIMP Balance as Therapeutic Target in Pulmonary Diseases, Letters in Drug Design & Discovery 2006; 3 (3) . https://dx.doi.org/10.2174/157018006776287005