Abstract
Over 300 million cases of malaria each year cause significant morbidity and mortality. Growing drugresistance among the Plasmodia that cause malaria motivates the development of additional anti-malarial drugs. This review summarizes the current state of knowledge about potential drug targets for malaria. The recently sequenced malaria genome data clarifies parasite metabolic pathways, and more metabolic targets have been identified.
Keywords: Malaria, drug targets, plasmodium, metabolism, genomics
Mini-Reviews in Medicinal Chemistry
Title: Drug Targets for Plasmodium falciparum: A Post-Genomic Review/Survey
Volume: 6 Issue: 2
Author(s): Iwei Yeh and Russ B. Altman
Affiliation:
Keywords: Malaria, drug targets, plasmodium, metabolism, genomics
Abstract: Over 300 million cases of malaria each year cause significant morbidity and mortality. Growing drugresistance among the Plasmodia that cause malaria motivates the development of additional anti-malarial drugs. This review summarizes the current state of knowledge about potential drug targets for malaria. The recently sequenced malaria genome data clarifies parasite metabolic pathways, and more metabolic targets have been identified.
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Cite this article as:
Yeh Iwei and Altman B. Russ, Drug Targets for Plasmodium falciparum: A Post-Genomic Review/Survey, Mini-Reviews in Medicinal Chemistry 2006; 6 (2) . https://dx.doi.org/10.2174/138955706775475957
DOI https://dx.doi.org/10.2174/138955706775475957 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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