Abstract
Most pathological conditions that result in human diseases are associated with altered gene expression. With the advent of new technologies that might control gene expression and a broader knowledge of transcription factors and pathways, new strategies have emerged that offer promising first results for therapeutical and experimental purposes. This review will focus on different inflammatory conditions of the lung, in which targeting the transduction of involved genes have been successfully attempted.
Keywords: Allergy, Inflammation, Lung, Transcription, Antisense, Decoy, SiRNA
Current Drug Targets
Title: Targeting Transcription: A New Concept of Anti-Inflammatory Therapy of Airway Diseases
Volume: 7 Issue: 6
Author(s): D. Quarcoo and E. Hamelmann
Affiliation:
Keywords: Allergy, Inflammation, Lung, Transcription, Antisense, Decoy, SiRNA
Abstract: Most pathological conditions that result in human diseases are associated with altered gene expression. With the advent of new technologies that might control gene expression and a broader knowledge of transcription factors and pathways, new strategies have emerged that offer promising first results for therapeutical and experimental purposes. This review will focus on different inflammatory conditions of the lung, in which targeting the transduction of involved genes have been successfully attempted.
Export Options
About this article
Cite this article as:
Quarcoo D. and Hamelmann E., Targeting Transcription: A New Concept of Anti-Inflammatory Therapy of Airway Diseases, Current Drug Targets 2006; 7 (6) . https://dx.doi.org/10.2174/138945006777435326
DOI https://dx.doi.org/10.2174/138945006777435326 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
Call for Papers in Thematic Issues
New drug therapy for eye diseases
Eyesight is one of the most critical senses, accounting for over 80% of our perceptions. Our quality of life might be significantly affected by eye disease, including glaucoma, diabetic retinopathy, dry eye, etc. Although the development of microinvasive ocular surgery reduces surgical complications and improves overall outcomes, medication therapy is ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Cancer Vaccines: Emphasis on Pediatric Cancers
Current Pharmaceutical Design Exploitation of Apoptosis Pathways for Childhood Leukemia
Current Pediatric Reviews Angiogenesis Inhibitors: Current & Future Directions
Current Pharmaceutical Design Studies on the IC<sub>50</sub> of Trisubstituted Thiazoles as Cdc7 Kinase Inhibitors
Letters in Drug Design & Discovery Induction of Abscopal Anti-Tumor Immunity and Immunogenic Tumor Cell Death by Ionizing Irradiation - Implications for Cancer Therapies
Current Medicinal Chemistry Annexins Bend Wound Edges during Plasma Membrane Repair
Current Medicinal Chemistry Novobiocin and Additional Inhibitors of the Hsp90 C-Terminal Nucleotide- binding Pocket
Current Medicinal Chemistry Progress in the Development of Matrix Metalloproteinase Inhibitors
Current Medicinal Chemistry New Vascular Disrupting Agents in Upper Gastrointestinal Malignancies
Current Medicinal Chemistry Editorial [Hot Topic: Imaging of Tumor Characteristics for Tailored Therapy (Executive Editor: Erik de Vries)]
Current Pharmaceutical Design Targeting Mevalonate Pathway in Cancer Treatment: Repurposing of Statins
Recent Patents on Anti-Cancer Drug Discovery Expression Microarray Proteomics and the Search for Cancer Biomarkers
Current Genomics Exosome-like Nanoparticles: A New Type of Nanocarrier
Current Medicinal Chemistry Synthesis, Characterization, and Molecular Structure of a Novel Zinc (II) Complex: Assessment of Impact of MDR1Pgp Expression on its Cytotoxic Activity
Medicinal Chemistry Anti-GD2 Antibody Therapy for GD2-Expressing Tumors
Current Cancer Drug Targets Bee Venom: Its Potential Use in Alternative Medicine
Anti-Infective Agents Role of Flavonoids in Future Anticancer Therapy by Eliminating the Cancer Stem Cells
Current Stem Cell Research & Therapy Dual EGFR and COX-2 Inhibition as a Novel Approach to Targeting Head and Neck Squamous Cell Carcinoma
Current Cancer Drug Targets Methods for Biomarker Verification and Assay Development
Current Proteomics Evaluation of Direct Effect of Testosterone on NGEP and LM O1 Expression in LNCaP Prostate Cancer Cells
Current Biomarkers (Discontinued)