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Current Hypertension Reviews

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ISSN (Print): 1573-4021
ISSN (Online): 1875-6506

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Review Article

New Genetic Polymorphisms as an Epidemiological Factor of Arterial Hypertension in Patients with Hyposodical Diet

Author(s): Sabina López-Toledo, Sergio A. Ramírez-García*, Carlos E. Cabrera-Pivaral, Luis Javier Flores-Alvarado, Dalia Madrigal Ruiz, María E. Aguilar Aldrete and Felipe Parada-Luna

Volume 18, Issue 1, 2022

Published on: 04 February, 2021

Page: [34 - 38] Pages: 5

DOI: 10.2174/1573402117666210204205447

Price: $65

Abstract

Hypertension is a major public health problem, affecting more than a quarter of the world's population causing serious cardiovascular problems. In recent years, different polymorphisms have been studied and helped to identify some candidate genes and hereditary syndromes associated with the molecular mechanisms involved in the development of hypertension. Therefore, it is important to identify these molecular mechanisms. This review exposes all the genes and polymorphisms that increase or decrease the risk of hypertension in different populations that are related to the renin angiotensin aldosterone system, G protein, salt excretion, aldosterone synthesis, lipid metabolism, mechanism of insulin resistance, vitamin metabolism, purines and sodium reabsorption. This document can be a useful tool in clinical practice, in addition to serving as a support for future research on this topic.

Keywords: Genetics, hypertension, polymorphism, epigenomics, epidemiology, haplotypes.

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