Comparison of Helicobacter pylori Detection Methods: It’s Association with Leukocytosis and Monocytosis

Title:Comparison of Helicobacter pylori Detection Methods: It’s Association with Leukocytosis and Monocytosis

Volume: 20 Issue: 6

Author(s): Monireh Rahimkhani*, Alireza Mordadi, Kiana Kazemian and Hourieh Khalili

Affiliation:

• Faculty of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran,Iran

Keywords: Helicobacter pylori, diagnosis methods, monocytosis, infection, Leukocytosis , gram-negative.

Abstract:

Background: Helicobacter pylori is a slow-growing micro-aerophilic gram-negative organism found in the stomach and duodenum. It is also associated with a number of stomach-duodenal diseases.

Material and Methods: There are invasive and non-invasive methods to detect Helicobacter pylori infections. In a 13-months period, 101 patients with clinical signs of infection confirmed by biopsy and Rapid Urease test as well as a culture were included in this study.

Results: There were significant correlations between breath urease test, anti-Helicobacter pylori serum IgG and IgA as well as fecal Helicobacter pylori Ag with the gold-standard method, (P=0.001) Moreover, there was a significant correlation between Monocytosis (P= 0.05) and goldstandard method.

Conclusion: Based on studies conducted on patients with Helicobacter pylori infection, noninvasive diagnostics methods can be useful in the diagnosis of Helicobacter infections rather than evaluating anti-Helicobacter pylori serum IgM and also increased blood monocytes could be a reliable confirmation for detection. Furthermore, Monocytosis must be considered as a Helicobacter pylori infection at the first step in an area with a high infected percentage.

Cite this article as:

Rahimkhani Monireh *, Mordadi Alireza , Kazemian Kiana and Khalili Hourieh , Comparison of Helicobacter pylori Detection Methods: It’s Association with Leukocytosis and Monocytosis, Infectious Disorders - Drug Targets 2020; 20 (6) . https://dx.doi.org/10.2174/1871526520666200707113955