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Infectious Disorders - Drug Targets

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ISSN (Print): 1871-5265
ISSN (Online): 2212-3989

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Review Article

Miracles of Herbal Phytomedicines in Treatment of Skin Disorders: Natural Healthcare Perspective

Author(s): Ashima Ahuja*, Jitendra Gupta and Reena Gupta

Volume 21, Issue 3, 2021

Published on: 22 June, 2020

Page: [328 - 338] Pages: 11

DOI: 10.2174/1871526520666200622142710

Price: $65

Abstract

Human skin is considered as the first line of defense and barrier against the majority of infections caused through the skin that affect humans. Healthy skin promotes a healthy body that can be achieved with the usage of modern, allopathic and natural remedies. Major skin ailments affecting humans are skin cancers, eczema, herpes infection, fungal infection, anti-aging, itching, insect bites, pemphigus vulgaris, trauma, psoriasis, athlete’s foot infections, rashes, skin pigmentation, acne, major and minor wound infections that are slowly becoming a burden on health care. Skin infections can be treated from sources that originate from animals and plants. In spite of advancements in science and technology, the emergence of natural herbal remedies for managing skin disorders has become a pivotal and essential contributor in treating skin infections due to increased demand for herbals and their lower price, and continuous adverse effects of modern medicines. In the recent era, herbal extracts and their phytomedicines have made a vital contribution to human health care. Herbal products nowadays are considered as a single line of treatment for many diseases like Cancers, Diabetes, Cardiovascular and Brain disorders, thereby creating awareness regarding purity, efficacy and safety of herbal medicines for health care management. Many therapeutically active natural herbal resources like Aloe, Neem, Liquorice, Tulsi, Amla, Papaya, Ginger and Eucalyptus are potent and safe in the treatment of dermatological infections. This review article summarizes the significance of herbal plants for protecting, treating and minimizing skin infections through the utility of herbal pharmaceuticals like creams, decocted extracts, poultice, paste and lotions that aid in the treatment of skin infections and diseases at a relatively lower cost with lesser side effects as compared to modern and allopathic medicines.

Keywords: Skin, natural remedies, dermatological infections, health care, phytoconstituents, skin disorders.

Graphical Abstract

[1]
Bhatia, M.; Siddiqui, N.A.; Gupta, S. Abrus precatorius (L.): An Evaluation of Traditional Herb. Indo Amer J Pharmaceu Res, 2013, 3(4), 3295-3315.
[2]
Parekh, J.; Jadeja, D.; Chandana, S. Efficacy of Aqueous and Methanol Extracts of Some Medicinal Plants for Potential Antibacterial Activity. Turk. J. Biol., 2005, 29, 203-210.
[3]
Mistry, K.; Mehta, M.; Mendpara, N.; Gamit, S.; Shah, G. Determination of Antibacterial Activity and MIC of Crude Extract of Abrus precatorius L. Advanced Biotech, 2010, 10(2), 25-27.
[4]
Gupta, P.; Kumar, A.; Sharma, N.; Patel, M.; Maurya, A.; Srivastava, S. A review on phytomedicines used in treatment of most common skin diseases. Indian J Drugs, 2017, 5(4), 150-164.
[5]
https://opentextbc.ca/anatomyandphysiology/chapter/5-1-layers-of-the-skin
[6]
Barry, B.W. Modern methods of promoting drug absorption through the skin. Mol. Aspects Med., 1991, 12(3), 195-241.
[http://dx.doi.org/10.1016/0098-2997(91)90002-4] [PMID: 1770837]
[7]
Lawrence, H.S. Nopper, Amy; Jo. Superficial Bacterial Skin Infections and Cellulitis. Princi Prac Paedia Infect Dis, 2018, pp. 436-444.
[8]
Hay, R.; Bendeck, S.E.; Chen, S.; Estrada, R.; Haddix, A.; Mcloed, T.; Mahe, A. Skin Diseases. Disease Control Priorities in Developing Countries. , 2nd ed; World Bank: Washington, DC, 2006, pp. 707-721.
[9]
Aghmiuni, A.I.; Khiavi, A.A. Medicinal Plants to Calm and Treat Psoriasis Disease., 2017.
[http://dx.doi.org/10.5772/67062]
[10]
Tabassum, N.; Hamdani, M. Medicinal Plants to Calm and Treat Psoriasis Disease Aromatic and medicinal plant, 2014.
[http://dx.doi.org/10.4103/0973-7847.125531]
[11]
Bhowmi, D. Chiranjib.; Yadav, J.; Tripathi, K. K., Kumar, K.P.S. Herbal Remedies of Azadirachta indica and its Medicinal Application. J. Chem. Pharm. Res., 2010, 2(1), 62-72.
[12]
Biswas, K.; Chattopadhyay, I.; Banerjee, R.K.; Bandyopadhyay, U. Biological activities and medicinal properties of neem (Azadirachta indica). Curr. Sci., 2002, 82(11), 1136-1345.
[13]
Lakshmi, T.; Krishnan, V.; Rajendran, R.; Madhusudhanan, N. Azadirachta indica: A herbal panacea in dentistry - An update. Pharmacogn. Rev., 2015, 9(17), 41-44.
[http://dx.doi.org/10.4103/0973-7847.156337] [PMID: 26009692]
[14]
Satralkar, S.; Zagade, T.B. Effectiveness of Application of Neem Paste on Face Acne among Teenagers in Selected Area of Sangli, Miraj and Kupwad Corporation. Intern J Sci Res, 2019, 8(6), 1387-1396.
[15]
Damle, M. Glycyrrhiza glabra (Liquorice) - a potent medicinal herb. Inter J Herbal Medi, 2014, 2(2), 132-136.
[16]
Akhtar, N.; Khan, H.M.S.; Iqbal, A.; Khan, B.A.; Bashir, S. Glycyrrhiza glabra extract cream: effects on skin pigment melanin International Conference on Bioscience, Biochemistry and Bioinformatics: IACSIT Press, Singapore, 2011, 5, pp. 434-439.
[17]
Saeedi, M.; Morteza-Semnani, K.; Ghoreishi, M.R. The treatment of atopic dermatitis with licorice gel. J. Dermatolog. Treat., 2003, 14(3), 153-157.
[http://dx.doi.org/10.1080/09546630310014369] [PMID: 14522625]
[18]
Radhakrishnan, N.; Gnanamani, A.; Sadulla, S. Effect of licorice (Glycyhrriza glabra linn.), a skin-whitening agent on black molly (poecilia latipinnaa) J appl cosmetol, 2005, 23, 149-158.
[19]
Kulkarni, K.V.; Adavirao, B.V. A review on: Indian traditional shrub Tulsi (Ocimum sanctum): The unique medicinal plant. J Medi Plants Studies, 2018, 6(2), 106-110.
[20]
Cohen, M.M. Tulsi - Ocimum sanctum: A herb for all reasons. J. Ayurveda Integr. Med., 2014, 5(4), 251-259.
[http://dx.doi.org/10.4103/0975-9476.146554] [PMID: 25624701]
[21]
Okhuarobo, A.; Falodun, J.E.; Erharuyi, O.; Imieje, V.; Falodun, A.; Langer, P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac. J. Trop. Dis., 2014, 4(3), 213-222.
[http://dx.doi.org/10.1016/S2222-1808(14)60509-0]
[22]
Kumar, K.P.S.; Bhowmik, D.; Dutta, A.; Yadav, A. Pd.; Paswan, S.; Srivastava, S.; Deb, L. Recent Trends in Potential Traditional Indian Herbs Emblica officinalis and Its Medicinal Importance. J Pharmacog Phytochem, 2012, 1(1), 24-32.
[23]
Khurana, S.K.; Tiwari, R.; Khan, S.; Yatoo, M.I.; Gugjoo, M.B.; Dhama, K. Emblica officinalis (Amla) with a Particular Focus on Its Antimicrobial Potentials: A Review. J. Pure Appl. Microbiol., 2019, 13(4), 1-18.
[http://dx.doi.org/10.22207/JPAM.13.4.11]
[24]
Dasaroju, S.; Gottumukkala, K.M. Current Trends in the Research of Emblica officinalis (Amla): A Pharmacological Perspective. Int. J. Pharm. Sci. Rev. Res., 2014, 24(2), 150-159.
[25]
Uchiyama, T.; Tsunenaga, M.; Miyanaga, M.; Ueda, O.; Ogo, M. Oral intake of lingonberry and amla fruit extract improves skin conditions in healthy female subjects: A randomized, double-blind, placebo-controlled clinical trial. Biotechnol. Appl. Biochem., 2019, 66(5), 870-879.
[http://dx.doi.org/10.1002/bab.1800] [PMID: 31342566]
[26]
Rajeswari, R.; Umadevi, M.; Rahale, C.S.; Puspha, R.; Kumar, S.; Bhowmik, D. Aloe vera: The Miracle Plant Its Medicinal and Traditional Uses in India. J Pharmacog Phytochem, 2012, 1(4), 118-124.
[27]
Kumar, K.P.S.; Bhowmik, D. Chiranjib.; Biswajit. Aloe vera: A Potential Herb and its Medicinal Importance. J. Chem. Pharm. Res., 2010, 2(1), 21-29.
[28]
Aravind, G.; Bhowmik, D.; Duraivel, S.; Harish, G. Traditional and Medicinal Uses of Carica papaya. J Medi Plants Stud, 2013, 1(1), 7-15.
[29]
Esimone, C.O.; Nworu, C.S.; Jackson, C.L. Cutaneous wound healing activity of a herbal ointment containing the leaf extract of Jatropha curcus L. (Euphorbiaceae). Int. J. Appl. Res. Nat. Prod., 2008, 1(4), 1-4.
[30]
Kazerouni, A.; Kazerouni, O.; Pazyar, N. Effects of Ginger (Zingiber officinale) on Skin Conditions: A Non Quantitative Review Article. J Turkish Aca Dermato, 2013, 7(2), 1-4.
[31]
Takahashi, T.; Kokubo, R.; Sakaino, M. Antimicrobial activities of eucalyptus leaf extracts and flavonoids from Eucalyptus maculata. Lett. Appl. Microbiol., 2004, 39(1), 60-64.
[http://dx.doi.org/10.1111/j.1472-765X.2004.01538.x] [PMID: 15189289]
[32]
Kumar S. Malhotra. R. Kumar D.. Euphorbia hirta: Its chemistry, traditional and medicinal uses, and pharmacological activities Pharmacog rev, 2010, 4(7), 58-61.
[33]
http://tropical.theferns.info/viewtropical.php?id=Euphorbia+hirta
[34]
Khan, H.; Akhtar, N.; Ali, A. Effects of Cream Containing Ficus carica L. Fruit Extract on Skin Parameters: In vivo Evaluation. Indian J. Pharm. Sci., 2014, 76(6), 560-564.
[PMID: 25593393]
[35]
Silva, A.P. Costa, W.A.; Salazar, M.; Bezerra, P.; Pires, F.; Ferreira, M.; Menezes, E.; Urbina, G.; Barbosa, J.; Nunes, De C. Commercial and therapeutic application of plant based fatty acids. Open I. Ed; , 2018, pp. 1-18.
[36]
Graf. J. Herbal Anti-Inflammatory Agents for Skin Disease In: Skin Therapy Letter: Vancouver Letter S.T. Ed; , 2000.
[37]
Huang, T.H.; Wang, P.W.; Yang, S.C.; Chou, W.L.; Fang, J.Y. Cosmetic and Therapeutic Applications of Fish Oil’s Fatty Acids on the Skin. Mar. Drugs, 2018, 16(8), 1-20.
[http://dx.doi.org/10.3390/md16080256] [PMID: 30061538]
[38]
Upadhyay, R.K. Nutraceutical, pharmaceutical and therapeutic uses of Allium cepa: A review. Inter J Green Phar, 2016, 10(1), S46-S64.
[39]
Kumar, K.P.S.; Bhowmik, D. Chiranjib; Biswajit; Tiwari, P. Allium cepa: A traditional medicinal herb and its health benefits. J. Chem. Pharm. Res., 2010, 2(1), 283-291.
[40]
Nadkarni, A.K.; Nadkarni, K.M. Indian Materia Medica. 3rd ed Popular Prakashan Bombay, India; , 1954, pp. 776-784.
[41]
Kirtikar, K.R.; Basu, B.D. Indian Medicinal Plants. International Book Distributors Dehradun; , 1956.
[42]
Kuo, S.C.; Chen, S.C.; Chen, L.H.; Wu, J.B.; Wang, J.P.; Teng, C.M. Potent antiplatelet, anti-inflammatory and antiallergic isoflavanquinones from the roots of Abrus precatorius. Planta Med., 1995, 61(4), 307-312.
[http://dx.doi.org/10.1055/s-2006-958089] [PMID: 7480175]
[43]
Nwodo, O.F.; Alumanah, E.O. Studies on Abrus precatorius seeds. II: Antidiarrhoeal activity. J. Ethnopharmacol., 1991, 31(3), 395-398.
[http://dx.doi.org/10.1016/0378-8741(91)90024-8] [PMID: 2056766]
[44]
Zeng, Qi.; Xie, H.; Song, H.; Nie, F.; Wang, J.; Chen, D.; Wang, Fu. In-vivo Wound Healing Activity of Abrus cantoniensis Extract. Evid Based Compplement Alterna Medi; , 2016, pp. 1-7.
[45]
http://www.carrotmuseum.co.uk/carrotoil.html
[46]
https://www.healthline.com/health/peppermint-oil-for-hair#benefits
[47]
Sharma, R.; Hooda, M. Essential Oils against Dandruff: An Alternative Treatment. Inter J Phar Chem Res, 2017, 3(2), 248-251.
[48]
Choudhury, H.; Pandey, M.; Hua, C.K.; Mun, C.S.; Jing, J.K.; Kong, L.; Ern, L.Y.; Ashraf, N.A.; Kit, S.W.; Yee, T.S.; Pichika, M.R.; Gorain, B.; Kesharwani, P. An update on natural compounds in the remedy of diabetes mellitus: A systematic review. J. Tradit. Complement. Med., 2017, 8(3), 361-376.
[http://dx.doi.org/10.1016/j.jtcme.2017.08.012] [PMID: 29992107]

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