Bioengineered polymers and nanomaterials have emerged as promising and advanced materials
for the fabrication and development of novel biosensors. Nanotechnology-enabled biosensor methods
have high sensitivity, selectivity and more rapid detection of an analyte. Biosensor based methods are
more rapid and simple with higher sensitivity and selectivity and can be developed for point-of-care diagnostic
testing. Development of a simple, sensitive and rapid method for sorbitol detection is of considerable
significance to efficient monitoring of diabetes-associated disorders like cataract, neuropathy, and
nephropathy at initial stages. This issue encourages us to write a review that highlights recent advancements
in the field of sorbitol detection as no such reports have been published till the date. The first section
of this review will be dedicated to the conventional approaches or methods that had been playing a
role in detection. The second part focused on the emerging field i.e. biosensors with optical, electrochemical,
piezoelectric, etc. approaches for sorbitol detection and the importance of its detection in
healthcare application. It is expected that this review will be very helpful for readers to know the different
conventional and recent detection techniques for sorbitol at a glance.
Keywords: Nanomaterials, Sorbitol detection, Polyols, Diabetes, Biosensor, Sorbitol dehydrogenase.
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