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Recent Patents on Drug Delivery & Formulation

Editor-in-Chief

ISSN (Print): 1872-2113
ISSN (Online): 2212-4039

Review Article

Nano-Based Drug Delivery System: Recent Strategies for the Treatment of Ocular Disease and Future Perspective

Author(s): Zufika Qamar, Farheen Fatima Qizilbash, Mohammad Kashif Iqubal, Asgar Ali, Jasjeet Kaur Narang, Javed Ali and Sanjula Baboota*

Volume 13, Issue 4, 2019

Page: [246 - 254] Pages: 9

DOI: 10.2174/1872211314666191224115211

Abstract

The structure of the eye is very complex in nature which makes it a challenging task for pharmaceutical researchers to deliver the drug at the desired sites via different routes of administration. The development of the nano-based system helped in delivering the drug in the desired concentration. Improvement in penetration property, bioavailability, and residence time has all been achieved by encapsulating drugs into liposomes, dendrimers, solid lipid nanoparticle, nanostructured lipid carrier, nanoemulsion, and nanosuspension. This review puts emphasis on the need for nanomedicine for ocular drug delivery and recent developments in the field of nanomedicine along with recent patents published in the past few years.

Keywords: Ocular drug delivery system, nanomedicine, hydrogels, solid lipid nanocarriers, nanostructured lipid carriers, nanoemulsion, inorganic nanoparticles, patents.

Graphical Abstract
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