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Review Article

Health Beneficial Potential of Pectolinarigenin on Human Diseases: An Updated Review of Medicinal Importance and Pharmacological Activity

Author(s): Kanika Patel and Dinesh Kumar Patel*

Volume 11, Issue 1, 2021

Published on: 11 November, 2019

Page: [3 - 12] Pages: 10

DOI: 10.2174/2210315509666191111110901

Price: $65

Abstract

Medicinal Plants are valuable source of phytochemicals which have been used in the medicine as source of raw material since very ancient time in the world. Flavonoids are one of the important classes of phytochemical basically present in the fruits, vegetables, grains, wine, tea etc. Flavonoids also play an important role in the defense mechanism of plants and produce different colours in the plants. Pectolinarigenin is a natural flavonoidal compound having molecular formula C17H14O6 and molecular weight 314.28. Pectolinarigenin is present in various plants and examples are Clerodendrum phlomidis, Eupatorium odoratum, Cirsium chanroenicum, Cirsium japonlcum, Chromolaena odorata, Cirsium setidens, and Trollius chinensis. Pectolinarigenin acts as an anticancer agent against various types of human malignancies, such as lung cancer, melanoma, hepatocellular carcinoma and colorectal adenocarcinoma. It has also anti-inflammatory, anti-allergy, cytotoxic and hepatoprotective properties. Pectolinarigenin gained attention from researchers and clinicians due to their anticancer properties and in future it could be the best choice for cancer treatment. The purpose of this review paper is to summarize all the pharmacological properties of pectolinarigenin on cancer and other disorders, describe the mode of action and possible pathways for cellular level action. The present review initially highlights the current status of flavonoids and their pharmaceutical importance, role of pectolinarigenin in human disorders, and in later section, summarizes analytical techniques of pectolinarigenin as lead molecules. This review will support all the ongoing research of pectolinarigenin through out world for their beneficial properties in all the scientific discipline.

Keywords: Analytical updates, anti-cancer, biological properties, flavonoids, herbal medicine, human diseases, pectolinarigenin, phytoconstituents, therapeutic uses.

Graphical Abstract

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