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Current Pediatric Reviews

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ISSN (Print): 1573-3963
ISSN (Online): 1875-6336

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Review Article

Biologics in Children with Allergic Diseases

Author(s): Amelia Licari, Sara Manti, Alessia Marseglia, Maria De Filippo, Elisabetta De Sando, Thomas Foiadelli and Gian Luigi Marseglia*

Volume 16, Issue 2, 2020

Page: [140 - 147] Pages: 8

DOI: 10.2174/1573396315666191029123822

Price: $65

Abstract

The prevalence of allergic diseases has been remarkably increased in the last decades. The global health burden of these conditions is substantial, since patients may experience disability, anxiety and emotional distress, social restrictions, and reduced quality of life and productivity, in particular, in the most severe cases. Recent advances in understanding the pathophysiology of allergic disorders have allowed identifying novel therapeutic strategies for the treatment of severe and uncontrolled allergic diseases. Although most studies have been performed in allergic asthma, biological drugs targeting other allergic diseases such as chronic spontaneous urticaria, atopic dermatitis, and food allergy are showing promising results. In this review, the most recent evidence on biologic therapies for allergic diseases, focusing on the pediatric age has been presented.

Keywords: Asthma, atopic dermatitis, biologics, children, chronic spontaneous urticaria, food allergy.

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