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Current Nutrition & Food Science

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ISSN (Print): 1573-4013
ISSN (Online): 2212-3881

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Research Article

Dietary Intake of Mycotoxin Susceptible Foods by Brazilian Nursing Mothers

Author(s): Karina M. Tonon, Mercedes G.R. Reiter, Milena de Oliveira Dutra, Geovana D. Savi and Vildes M. Scussel*

Volume 16, Issue 6, 2020

Page: [953 - 962] Pages: 10

DOI: 10.2174/1573401315666191009094147

Price: $65

Abstract

Background: The human milk has several health benefits to the mother and child, and it is the ideal form of nutrition for infants. However, some food contaminants such as mycotoxins can be transferred from the mother to the child through breast milk.

Objective: To access the dietary intake of mycotoxin susceptible foods by nursing mothers.

Methods: The dietary intake of mycotoxin susceptible foods was investigated by interviewing nursing mothers (n = 86), who were registered donors of the Human Milk Bank (HMB) of Blumenau (Brazil), through a food frequency questionnaire (FFQ). The mothers were contacted and those who agreed to answer the FFQ were recruited for the study group. The interview was conducted individually, face to face with each mother, by a trained researcher. The FFQ was divided into three food Groups (vegetables, animal and beverages, respectively), considered most prone to mycotoxins contamination. Socio-demographic characteristics of the mothers were also obtained.

Results: The FFQ revealed a high weekly intake of foods susceptible to fungi and mycotoxin contamination. Consumption of wheat, coffee and cow’s milk was reported by 52, 44 and 51% of the mothers, respectively. The consumption of those foods occurred daily to more than 7 times per week.

Conclusion: The study revealed that Brazilian nursing mothers frequently consume foods susceptible to mycotoxin contamination, especially wheat and its by-products. Brazilian health, environmental and agriculture authorities should pay permanent attention by applying monitoring programs to grains and cereals - both imported and domestically produced - as they are highly susceptible to fungi and mycotoxin contamination, which can be transferred to infants via breastfeeding, apart from harming the general population health.

Keywords: Dietary habits, food safety, human milk, mycotoxins, nursing mothers, socio-demographic profile, contamination.

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[1]
Arenz S, Von Kries R. Protective effect of breast-feeding against obesity in childhood: Can a meta-analysis of published observational studies help to validate the hypothesis? Adv Exp Med Biol 2009; 639: 145-52.
[http://dx.doi.org/10.1007/978-1-4020-8749-3_12] [PMID: 19227541]
[2]
Hausner H, Nicklaus S, Issanchou S, Mølgaard C, Møller P. Breastfeeding facilitates acceptance of a novel dietary flavour compound. Clin Nutr 2010; 29(1): 141-8.
[http://dx.doi.org/10.1016/j.clnu.2009.11.007] [PMID: 19962799]
[3]
Li SC, Kuo SC, Hsu YY, Lin SJ, Chen PC, Chen YC. Effect of breastfeeding duration on infant growth until 18 months of age: a national birth cohort study. J Exp Clin Med 2010; 2: 165-72.
[http://dx.doi.org/10.1016/S1878-3317(10)60026-5]
[4]
Oddy WH, Robinson M, Kendall GE, Li J, Zubrick SR, Stanley FJ. Breastfeeding and early child development: A prospective cohort study. Acta Paediatr 2011; 100(7): 992-9.
[http://dx.doi.org/10.1111/j.1651-2227.2011.02199.x] [PMID: 21299610]
[5]
Østbye T, Krause KM, Swamy GK, Lovelady CA. Effect of breastfeeding on weight retention from one pregnancy to the next: Results from the North Carolina WIC program. Prev Med 2010; 51(5): 368-72.
[http://dx.doi.org/10.1016/j.ypmed.2010.07.017] [PMID: 20655944]
[6]
Landrigan PJ, Sonawane B, Mattison D, Mccally M, Garg A. Chemical contaminants in breast milk and their impacts on children’s health: An overview mini-monograph. Environ Health 2002; 110: 313-5.
[7]
Mead MN. Contaminants in human milk: Weighing the risks against the benefits of breastfeeding. Environ Health Perspect 2008; 116(10): A427-34.
[http://dx.doi.org/10.1289/ehp.116-a426] [PMID: 18941560]
[8]
Tonon KM, Reiter MGR, Scussel VM. Mycotoxins levels in human milk: A menace to infants and children health. Curr Nutr Food Sci 2013; 55: 33-42.
[9]
CAST. Mycotoxins: risks in plant, animal and human systems In: Council for Agricultural Science and Technology, Report no 139 Ames lowa USA 2003; p 199
[10]
McQueen CA. Comprehensive toxicology. 3rd ed. Kidlington: Elsevier 2017.
[11]
Rai M, Varma A. Mycotoxins in food, feed and bioweapons. 1st ed. Berlin: Springer-Verlag 2010.
[http://dx.doi.org/10.1007/978-3-642-00725-5]
[12]
Scussel VM, Beber M, Tonon KM. Efeito da infecção por Fusarium / Gibberella zeae na qualidade e segurança de grãos de inverno.In: Reis MR, Ed.Seminario em Giberella em Cereais de inverno. Passo Fundo, RS, Brazil 2011; pp. 131-75.
[13]
van Egmond HP, Schothorst RC, Jonker MA. Regulations relating to mycotoxins in food: Perspectives in a global and European context. Anal Bioanal Chem 2007; 389(1): 147-57.
[http://dx.doi.org/10.1007/s00216-007-1317-9] [PMID: 17508207]
[14]
IARC Some traditional herbal medicines: Some mycotoxins, naphthalene and styrene IARC Monograph on the Evaluation of Carcinogenic Risks to Humans In: World Health Organization Lyon, France 2002; 82: p 590.
[15]
Pestka JJ. Deoxynivalenol:Mechanisms of action, human exposure, and toxicological relevance. Arch Toxicol 2010; 84(9): 663-79.
[http://dx.doi.org/10.1007/s00204-010-0579-8] [PMID: 20798930]
[16]
Tonon KM, Reiter MGR, Savi GD, Scussel VM. Human milk AFM1, OTA, and DON evaluation by LC tandem mass specrometry and their relation to the Southern Brazil nursing mothers’ diet. J Food Saf 2018; 38: 1-8.
[http://dx.doi.org/10.1111/jfs.12452]
[17]
Muñoz K, Campos V, Blaszkewicz M, et al. Exposure of neonates to ochratoxin A: First biomonitoring results in human milk (colostrum) from Chile. Mycotoxin Res 2010; 26(2): 59-67.
[http://dx.doi.org/10.1007/s12550-009-0040-0] [PMID: 23605309]
[18]
Ribeiro AC, Sávio KEO, Rodrigues MLCF, Costa THM, Schmitz BAS. Validação de um questionário de freqüência de consumo alimentar para população adulta. Rev Nutr 2006; 19: 553-62.
[http://dx.doi.org/10.1590/S1415-52732006000500003]
[19]
Tonon KM, Reiter MGR, Scussel VM. Occurrence of filamentous fungi in human milk, infant formula and milk-based products for young children nutrition. Int J Food Sci Biotechnol 2017; 2: 80-6.
[20]
Galvano F, Pietri A, Bertuzzi T, et al. Maternal dietary habits and mycotoxin occurrence in human mature milk. Mol Nutr Food Res 2008; 52(4): 496-501.
[http://dx.doi.org/10.1002/mnfr.200700266] [PMID: 18338407]
[21]
Nazari L, Pattori E, Terzi V, Morcia C, Rossi V. Influence of maize–wheat rotation systems on Fusarium head blight infection and deoxynivalenol content in wheat under low versus high disease pressure. Food Microbiol 2014; 39: 19-26.
[http://dx.doi.org/10.1016/j.fm.2013.10.009] [PMID: 24387848]
[22]
Barkai-Golan R, Paster N. Mycotoxins in Fruits and Vegetables. 1st ed. London: Academic Press 2008.
[23]
Jager AV, Tedesco MP, Souto PCMC, Oliveira CAF. Assessment of aflatoxin intake in São Paulo, Brazil. Food Control 2013; 33: 87-92.
[http://dx.doi.org/10.1016/j.foodcont.2013.02.016]
[24]
Pacheco AM, Scussel VM. Selenium and aflatoxin levels in raw Brazil nuts from the Amazon basin. J Agric Food Chem 2007; 55(26): 11087-92.
[http://dx.doi.org/10.1021/jf072434k] [PMID: 18052094]
[25]
Fernández-Cruz ML, Mansilla ML, Tadeo JL. Mycotoxins in fruits and their processed products: Analysis, occurrence and health implications. Int J Adv Res (Indore) 2010; 2: 113-22.
[26]
Battilani P, Magan N, Logrieco A. European research on ochratoxin A in grapes and wine. Int J Food Microbiol 2006; 111(Suppl. 1): S2-4.
[http://dx.doi.org/10.1016/j.ijfoodmicro.2006.02.007] [PMID: 16712998]
[27]
Chulze SN, Magnoli CE, Dalcero AM. Occurrence of ochratoxin A in wine and ochratoxigenic mycoflora in grapes and dried vine fruits in South America. Int J Food Microbiol 2006; 111(Suppl. 1): S5-9.
[http://dx.doi.org/10.1016/j.ijfoodmicro.2006.02.006] [PMID: 16716424]
[28]
Hoeltz M, Monezzi LP, Manfroi V, Noll IB, Dottori HA, Ochratoxin A. Quality analysis of Brazilian and imported wines. Braz J Food Technol 2012; 5: 58-63.
[http://dx.doi.org/10.1590/S1981-67232012005000039]
[29]
Kostelanska M, Zachariasova M, Lacina O, Fenclova M, Kollos AL, Hajslova J. The study of deoxynivalenol and its masked metabolites fate during the brewing process realised by UPLC-TOFMS method. Food Chem 2011; 126(4): 1870-6.
[http://dx.doi.org/10.1016/j.foodchem.2010.12.008] [PMID: 25213970]
[30]
Pan D, Bonsignore F, Rivas F, Perera G, Bettucci L. Deoxynivalenol in barley samples from Uruguay. Int J Food Microbiol 2007; 114(2): 149-52.
[http://dx.doi.org/10.1016/j.ijfoodmicro.2006.08.006] [PMID: 17067710]
[31]
Scussel VM, Rokka M, Rizzo A, Jestoi M, Peltonen K. Characterization of DON and DON-3-β-D-glucopyranoside through accurate mass measurement by quadrupole-time-of-flight mass spectrometry. Int J Environ Anal Chem 2013; 93: 61-74.
[http://dx.doi.org/10.1080/03067319.2011.629345]
[32]
Cea J, Martinez O. Relationship between the level of deoxynivalenol contamination in wheat and fungal infection. Rev Lab Tecnol Uruguay Innotec 2006; 1: 22.
[33]
Lori GA, Sisterna MN, Haidukowski M, Rizzo I. Fusarium graminearum and deoxynivalenol contamination in the durum wheat area of Argentina. Microbiol Res 2003; 158(1): 29-35.
[http://dx.doi.org/10.1078/0944-5013-00173] [PMID: 12608577]
[34]
Pan D, Graneri J, Bettucci L. Correlation of rainfall and levels of deoxynivalenol in wheat from Uruguay, 1997-2003. Food Addit Contam Part B Surveill 2009; 2(2): 162-5.
[http://dx.doi.org/10.1080/02652030903213886] [PMID: 24785179]
[35]
Goswami RS, Kistler HC. Heading for disaster: Fusarium graminearum on cereal crops. Mol Plant Pathol 2004; 5(6): 515-25.
[http://dx.doi.org/10.1111/j.1364-3703.2004.00252.x] [PMID: 20565626]
[36]
Aringoli EE, Cambiagno DE, Chiericatti CA, Basilico JC, Basilico MLZ. Mycoflora study in a wheat flour mill of Argentina. Braz J Microbiol 2012; 43(4): 1444-51.
[http://dx.doi.org/10.1590/S1517-83822012000400028] [PMID: 24031975]
[37]
Broggi LE, Pacin AM, Gasparovic A, et al. Natural occurrence of aflatoxins, deoxynivalenol, fumonisins and zearalenone in maize from Entre Ríos Province, Argentina. Mycotoxin Res 2007; 23(2): 59-64.
[http://dx.doi.org/10.1007/BF02946026] [PMID: 23605907]
[38]
Calori-Domingues MA, de Almeida RR, Tomiwaka MM, Gallo CR, Da Gloria EM, Dias CTS. Ocorrência de desoxinivalenol em trigo nacional e importado utilizado no Brasil. Food Sci Technol (Campinas) 2007; 27: 181-5.
[http://dx.doi.org/10.1590/S0101-20612007000100032]
[39]
Pacin A, Bovier EC, Cano G, Taglieri D, Pezzani CH. Effect of the bread making process on wheat flour contaminated by deoxynivalenol and exposure estimate. Food Control 2010; 21: 492-5.
[http://dx.doi.org/10.1016/j.foodcont.2009.07.012]
[40]
Del Ponte EM, Garda-Buffon J, Badiale-Furlong E. Deoxynivalenol and nivalenol in commercial wheat grain related to Fusarium head blight epidemics in southern Brazil. Food Chem 2012; 132: 1087-91.
[http://dx.doi.org/10.1016/j.foodchem.2011.10.108]
[41]
Sifuentes dos Santos J, Souza TM, Ono EYS, et al. Natural occurrence of deoxynivalenol in wheat from Paraná State, Brazil and estimated daily intake by wheat products. Food Chem 2013; 138(1): 90-5.
[http://dx.doi.org/10.1016/j.foodchem.2012.09.100] [PMID: 23265460]
[42]
Afshar P, Shokrzadeh M, Kalhori S, Babaee Z, Saeedi Saravi SS. Occurrence of ochratoxin A and aflatoxin M1 in human breast milk in Sari, Iran. Food Control 2013; 31: 525-9.
[http://dx.doi.org/10.1016/j.foodcont.2012.12.009]
[43]
Biasucci G, Calabrese G, Di Giuseppe R, et al. The presence of ochratoxin A in cord serum and in human milk and its correspondence with maternal dietary habits. Eur J Nutr 2011; 50(3): 211-8.
[http://dx.doi.org/10.1007/s00394-010-0130-y] [PMID: 20812016]
[44]
Gürbay A, Girgin G, Sabuncuoğlu SA, et al. Ochratoxin A: Is it present in human breast milk samples obtained mothers from Ankara, Turkey. Toxicol Lett 2009; 189: S232.
[http://dx.doi.org/10.1016/j.toxlet.2009.06.498]
[45]
Gürbay A, Sabuncuoğlu SA, Girgin G, et al. Exposure of newborns to aflatoxin M1 and B1 from mothers’ breast milk in Ankara, Turkey. Food Chem Toxicol 2010; 48(1): 314-9.
[http://dx.doi.org/10.1016/j.fct.2009.10.016] [PMID: 19850097]
[46]
Mahdavi R, Nikniaz L, Arefhosseini SR, Vahed Jabbari M. Determination of aflatoxin M(1) in breast milk samples in Tabriz-Iran. Matern Child Health J 2010; 14(1): 141-5.
[http://dx.doi.org/10.1007/s10995-008-0439-9] [PMID: 19093194]
[47]
Sadeghi N, Oveisi M, Jannat B, Hajimahmoodi M, Bonyani H, Jannat F. Incidence of aflatoxin M1 in human breast milk in Tehran, Iran. Food Control 2009; 20: 75-8.
[http://dx.doi.org/10.1016/j.foodcont.2008.02.005]
[48]
Turconi G, Guarcello M, Livieri C, et al. Evaluation of xenobiotics in human milk and ingestion by the newborn--an epidemiological survey in Lombardy (Northern Italy). Eur J Nutr 2004; 43(4): 191-7.
[http://dx.doi.org/10.1007/s00394-004-0458-2] [PMID: 15309437]
[49]
Londono VAG, Boasso AC, Paula MCZ, et al. Aflatoxin M1 survey on randomly collected milk powder commercialized in Argentina and Brazil. Food Control 2013; 34: 752-5.
[http://dx.doi.org/10.1016/j.foodcont.2013.06.030]
[50]
Elaridi J, Bassil M, Kharma JA, Daou F, Hassan HF. Analysis of aflatoxin M1 in breast milk and its association with nutritional and socioeconomic status of lactating mothers in Lebanon. J Food Prot 2017; 80(10): 1737-41.
[http://dx.doi.org/10.4315/0362-028X.JFP-17-083] [PMID: 28922028]
[51]
Yu X, Li Z, Zhao M, et al. Quantification of aflatoxin B1 in vegetable oils using low temperature clean-up followed by immunomagnetic solid phase extraction. Food Chem 2019; 275: 390-6.
[http://dx.doi.org/10.1016/j.foodchem.2018.09.132] [PMID: 30724212]

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