Background: In this present investigation, some 2, 3 disubstituted-quinazolin-4-one derivatives
are designed and docked against chain A and chain B of (3WDF) receptor.
Methods: The heterocyclic fused rings quinazolinone have drawn a great attention owing to their
expanded applications in the field of pharmaceutical chemistry. The diverse range of molecules
with quinazoline/quinazolinone moieties have been reported to exhibit a broad spectrum of biological
Results and Conclusion: The results designate that the quinazolinone ring forms hydrophobic and
hydrogen bond contacts with ASN 127 A, ALA 126 A, and SER 83 B, SER 183 B amino acid residue.