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Current Cancer Therapy Reviews

Editor-in-Chief

ISSN (Print): 1573-3947
ISSN (Online): 1875-6301

Research Article

Development, Characterization and Anticancer Evaluation of Silver Nanoparticles from Dalbergia sissoo Leaf Extracts

Author(s): Aakash Deep*, Mitali Verma, Rakesh K. Marwaha, Arun K. Sharma and Beena Kumari

Volume 16, Issue 2, 2020

Page: [145 - 151] Pages: 7

DOI: 10.2174/1573394715666190820150651

Abstract

Aim: The objective behind this present work is the development and characterization of silver nanoparticles from Dalbergia sissoo leaf extracts and the analysis of anticancer activity.

Methods: Silver nanoparticles were prepared by using the aqueous solution of Dalbergia sisoo leaf extract and silver nitrate. The formation of nanoparticles was determined by the color change during the preparation of plant extract to metal ion in a fixed ratio. The prepared nanoparticles were then characterized by TEM, FTIR, DLS, XRD, and SEM. Silver nanoparticles were also evaluated for anticancer activity.

Results: Synthesized silver nanoparticles were having good anticancer activity against MCF 7 cancer cell line as compared to the standard drug Doxorubicin.

Conclusion: The particle size of nanoparticles was found to lie in the range of 10 to 50 nm.

Keywords: Nanotechnology, nanoparticles, green synthesis, Dalbergia sisoo leaf extract, AgNPs, AuNPs.

Graphical Abstract
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