Backround; Fever is known as pyrexia may occur due to infection, inflammation, or any tissue damage and diseases states. Normally the infected or damaged tissue initiates the enhanced formation of pro-inflammatory mediators like cytokines which further increase the synthesis of prostaglandin E2 (PgE2) near hypothalamic area and thereby trigger the hypothalamus to elevate the body temperature.
Objective; Antipyretics are the agents which reduce the elevated body temperature. Most commonly used antipyretic agent paracetamol may be fatal due to its side effects.
Methods; In this review paper, Chemical abstract, Google Scholar, PubMed, Science Direct, were the sources to collect information regarding antipyretic activity.
Results; This review compiles antipyretic plants that may be useful to treat fever which are used traditionally. These medicinal plants could be good alternatives for traditional allopathic antipyretics.