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Current Proteomics

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ISSN (Print): 1570-1646
ISSN (Online): 1875-6247

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Review Article

The Applications of Clustering Methods in Predicting Protein Functions

Author(s): Weiyang Chen*, Weiwei Li, Guohua Huang* and Matthew Flavel

Volume 16, Issue 5, 2019

Page: [354 - 358] Pages: 5

DOI: 10.2174/1570164616666181212114612

Price: $65

Abstract

Background: The understanding of protein function is essential to the study of biological processes. However, the prediction of protein function has been a difficult task for bioinformatics to overcome. This has resulted in many scholars focusing on the development of computational methods to address this problem.

Objective: In this review, we introduce the recently developed computational methods of protein function prediction and assess the validity of these methods. We then introduce the applications of clustering methods in predicting protein functions.

Keywords: Clustering, protein function prediction, protein-protein interaction, protein complexes, computational methods, topology.

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