Author(s): Olen R. Brown
eISBN: 978-1-68108-697-2, 2018
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Poisons, due to their lethal nature, invoke a sense of fear in humans. Yet, they have also impacted other aspects of human life. Poisons have been used by nomadic hunters to kill their prey, by scientists to explore complex biochemical mechanisms of the body, by physicians to lower cholesterol and to kill cancer cells, by farmers and the general public to destroy pests, by the evil minded for homicide, and by tyrants as weapons of war.
The Art and Science of Poisons presents two facets of poisons: the science behind them and their place in history and art. The science of poisons describes their biochemistry and how they kill. The science story voyages into the sub-microscopic world of atoms, molecules, and cells. Only there can we see the true miracles and mysteries of life and death. Chapters in the book explore poisons from snakes, spiders, scorpions, sea creatures, as well as poisons made by humans in the laboratory, and those which are derived from beautiful plants.
The art of poisons, on the other hand, encompasses everything else about these agents that conjures up the image of the skull and crossbones. This side of the story explores the legends and tales of intrigue and surreptitious deaths of well-known personalities such as Socrates, Cleopatra, Hitler, and many more.
General readers with a curiosity about science and an interest in history and human nature will enjoy both facets presented in this brief, yet varied exploration into the world of poisons.
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Author(s): Chengming Wang, Bernhard Kaltenboeck and Mark D. Freeman
eISBN: 978-1-60805-348-3, 2018
PCR (Polymerase Chain Reaction) technology has become an indispensable component of routine veterinary diagnostics. However, a number of pitfalls and limiting factors affect its sensitivity and specificity of detection. It is imperative that veterinary PCR diagnosticians include such considerations in their work. Extensive experience with PCR technology in both research and diagnostic applications enables researchers to pinpoint these practical limitations, and therefore instruct the user in approaches that avoid these common errors.
This E-book discusses the basic concepts, chemistries, and instrumentation of standard and real-time PCR, and includes present applications and future perspectives for veterinary diagnostics. Critical pitfalls have been highlighted in this text with regard to veterinary PCR diagnostics which include: i) choice of platform technologies for PCR diagnosis; ii) construction of optimized PCR primers and probes to ensure its highest specificity and sensitivity; iii) correct sampling and efficient methods to preserve and release nucleic acids; iv) maximization of PCR amplification efficiency; and v) avoidance and monitoring of contamination in Veterinary PCR Diagnostics. This eBook should be a valuable reference for all veterinary professionals interested in this modern diagnostic tool.
Editor(s): Alessandra Pagliarani, Fabiana Trombetti and Vittoria Ventrella
eISBN: 978-1-60805-265-3, 2018
Organotins are widespread contaminants especially of water environments. Their chemically versatile structure makes organotin compounds able to bind to a variety of biomolecules thus widely affecting biological functions. Trisubstituted molecules, namely tributyltin (TBT) and triphenyltin (TPhT), have been widely employed in antifouling paints and are also exploited as plastic stabilizers that unfortunately cause harmful biological effects. Persistent bioaccumulation has resulted in organotins becoming a significant environmental threat. Chapter by chapter, the biological and biochemical effects of organotins are unravelled in this e-book by a careful analysis of the most recent findings with special focus on contaminant action mechanisms at cellular and molecular level. The e-book provides an intriguing insight into the molecular mechanisms involved in organotin toxicology thus serving as a useful reference to biochemists, biologists, ecotoxicologists and life science students.
Author(s): Dileep K. Singh
eISBN: 978-1-60805-137-3, 2018
ISBN: 978-1-60805-531-9 ISSN: 2211-2952 (Online)
Pesticide control involves killing pest organisms or otherwise preventing them from destructive behavior. Pesticides are either natural or synthetic and are applied to target pests in a myriad of formulations (EC,WP, SP, FP, G etc.) and application technology systems (sprays, baits, slow-release diffusion, dust, etc.). In recent years, the bacterial genes coding for insecticidal proteins have been incorporated into various crops that dealt with the mortality of the pests feeding on them. Many other eco-friendly methods for insect pest control such as Integrated Pest Management (IPM), use of bio-pesticides etc., are becoming popular. Bio-pesticides and IPM should show good growth in the future, as there is growing concern for the eco-friendly organic agriculture and could be achieved through Good Agriculture Practices (GAP).
Use of pesticides requires a proper understanding of the chemistry, their handling and their use in crop protection or hygiene. These are toxic chemicals and require a good understanding of therapy and antidotes at the time of poisoning. This e-book covers pesticide chemistry, metabolic/degradation pathways, biochemical toxicology, therapy and antidotes, nano-pesticides and terminologies associated with pesticide toxicology. The book should serve as a text book for academia, or as a reference work for agriculturists, environmentalists and industry professionals.
Editor(s): Benedict C. Albensi
eISBN: 978-1-60805-257-8, 2018
The main theme of this book is to critically survey the role of two recognized protein molecules (i.e., transcription factors) in processes of human memory. In addition, authors provided recent data from their own labs and provided a perspective relevant to specific neurological diseases and potential drug targets. Historically, the transcription factor cAMP response element-binding (CREB) has been the most well documented transcription factor shown to play a role in memory. CREB has several functions, but its most notable function has to do with the formation of long-term memories. More recently, other transcription factors, such as C/EBP, Egr protein, AP-1, and NF-κB have been implicated in memory as well. Of these, scientific literature on NF-κB’s theorized role in synaptic plasticity and memory is growing rapidly. Interestingly, in some recent studies CREB and NF-κB have also been shown to interact with each other where both contribute in a cooperative fashion to the initiation of gene expression.
Editor(s): Vincenzo Vacante
Co-Editor(s): Uri Gerson
eISBN: 978-1-60805-294-3, 2018
This book presents a definitive exposition of citrus pests and their integrated, mostly non-chemical , control in the Mediterranean area. This is the first book on this topic written by experts from various countries around the Mediterranean region. It provides useful information about the different agricultural management methods and how they impact pest control on various citrus plant species and varieties grown in the aforementioned region. The volume also describes methods of pest sampling, monitoring practices and determining the pests' economic thresholds. Special features of this text include updated data on various pests, their damage and control methods, key identification methods and a relevant glossary. The e-book should be a comprehensive guide for readers interested in citrus crops and integrated pest management.
Editor(s): Adaucto Bellarmino Pereira-Netto
eISBN: 978-1-60805-298-1, 2018
Brassinosteroids: Practical Applications in Agriculture and Human Health provides a comprehensive overview on the practical applications of brassinosteroids (BRs) in plant biology (including stress tolerance, growth and development) and human health (anticancer, antiviral and anti-inflammatory activity). The book assures readers a high-quality review of practical applications with a selection of contributions from an international panel of expert researchers. The book suggests new opportunities for professionals to effectively increase the supply of quality food and other plant-derived products, and to improve human health. This book is a reference guide for the performance and interpretation of applications of brassinosteroids to agronomists, chemists, physicians and plant physiologists.
Author(s): Anastasios K. Markopoulos
eISBN: 978-1-60805-113-7, 2018
This textbook provides a comprehensive overview of the part of dentistry that links basic physiologic and pathophysiologic mechanisms to frequently encountered problems in dental practice. Themes that are covered include the structure and function of the cells of oral mucosa, the biology of bone, the functions of oral mucosa, some important aspects on oral microbial flora and biofilms and finally the current principles on mastication, swallowing and speech. The knowledge of basic sciences is essential in oral biology, helping to understand the nature and behavior of cells, tissues and organs in health and disease. It is an easy-to-read, relatively brief but a comprehensive Ebook appropriate for undergraduate and graduate dental students as well as for practicing clinicians.
Editor(s): S.C Tjong
eISBN: 978-1-60805-040-6, 2018
This authoritative reference provides update information on the fundamental aspects and applications of biomaterials and biomedical sciences. It includes nickel-titanium alloys with superelasticity and shape memory effect, bioactive bone cement for orthopedic applications, and new research trends in polymer nanocomposites. This Ebook also describes the response of cells to ionizing radiation such as DNA damage responses in zebrafish. With chapters contributed by eminent scientists in the field of biophysics, biomaterials and biomedical engineering, this is a useful reference for graduate students, researchers and professionals in biomedical sciences and technologies.
Editor(s): Francisco Sánchez-Bayo, Paul J. van den Brink and Reinier M. Mann
eISBN: 978-1-60805-121-2, 2018
Ecological Impacts of Toxic Chemicals presents a comprehensive, yet readable account of the known disturbances caused by all kinds of toxic chemicals on both aquatic and terrestrial ecosystems. Topics cover the sources of toxicants, their fate and distribution through the planet, their impacts on specific ecosystems, and their remediation by natural systems. Each chapter is written by well-known specialists in those areas, for the general public, students, and even scientists from outside this field. The book intends to raise awareness of the dangers of chemical pollution in a world dominated by industry and globalization of resources. Because the problems are widespread and far reaching, it is hoped that confronting the facts may prompt better management practices at industrial, agricultural and all levels of management, from local to governmental, so as to reduce the negative impacts of chemical contaminants on our planet.
Editor(s): Anthony N. Rezitis
eISBN: 978-1-60805-263-9, 2018
ISBN: 978-1-60805-699-6 ISSN: 1879-7415 (Online)
The aim of this e-book series is to publish high quality economic research in agricultural and applied economics. It particularly fosters quantitative studies which make original contribution on important economic issues, the results of which help to understand and solve real economic problems. This volume contains research papers focusing on the areas of agricultural policy, agricultural price volatility, agricultural finance and cooperatives, consumption economics, firm production and organization, human capital convergence, international economics and multinational business, investment decisions in organic agriculture, market structure and industry studies. The research papers of this volume make use of recent methodological approaches and provide conclusions which are useful to both private sector participants and policy-makers.
eISBN: 978-1-60805-098-7, 2018
ISBN: 978-1-60805-397-1 ISSN: 1879-7415 (Online)
The aim of the eBook series of Research Topics in Agricultural & Applied Economics (RTAAE) is to publish high quality economic researches applied to both the agricultural and non-agricultural sectors of the economy. The subject areas of this eBook series include, among others, supply and demand analysis, technical change and productivity, industrial organization, labor economics, growth and development, environmental economics, marketing, business economics and finance. By covering a broad variety of economic research topics, this eBook series should prove to be of considerable interest to a wide spectrum of academic, agricultural and applied economic researchers and scientists, as well as to industry specialists and government policy makers.
eISBN: 978-1-60805-243-1, 2018
ISBN: 978-1-60805-698-9 ISSN: 1879-7415 (Online)
The aim of the Ebook series of Research Topics in Agricultural & Applied Economics (RTAAE) is to publish high quality economic researches applied to both the agricultural and non-agricultural sectors of the economy. The subject areas of this Ebook series include, among others, supply and demand analysis, technical change and productivity, industrial organization, labor economics, growth and development, environmental economics, marketing, business economics and finance. By covering a broad variety of economic research topics, this Ebook series should prove to be of considerable interest to a wide spectrum of academic, agricultural and applied economic researchers and scientists, as well as to industry specialists and government policy makers.