Progressive Supranuclear Palsy: Neuropsychopathological, Therapeutical and Bioethical Aspects

Author(s): Ignazio Vecchio, Cristina Tornali, Giulia Malaguarnera, Nicola Luigi Bragazzi, Michele Malaguarnera*.

Journal Name: Current Alzheimer Research

Volume 15 , Issue 10 , 2018

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Abstract:

The progressive supranuclear palsy is a progressive neurodegenerative disease characterized by Parkinsonism, oculomotor abnormalities, early postural instability and cognitive impairment. Neurodegeneration in PSP is associated with tau protein, but the mechanisms by which tau abnormalities lead to cell dysfunction and death are not well understood.

Neuro-behavioural problems related to the fear and loss of autonomy can determinate many bioethical implications. Careful planning involving patients’ families, academic and industry researchers were necessary to ensure improvement in quality of life.

Keywords: Progressive supranuclear palsy, tonopathy, movement disorders, bioethics, clinical ethics, cognitive disease.

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Article Details

VOLUME: 15
ISSUE: 10
Year: 2018
Page: [959 - 963]
Pages: 5
DOI: 10.2174/1567205015666180507111958
Price: $58

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