Synthesis of Substituted Phenols via Hydroxylation of Arenes Using Hydrogen Peroxide in the Presence of Hexaphenyloxodiphosphonium Triflate

Title:Synthesis of Substituted Phenols via Hydroxylation of Arenes Using Hydrogen Peroxide in the Presence of Hexaphenyloxodiphosphonium Triflate

Volume: 15 Issue: 10

Author(s): Mohammad Mehdi Khodaei*, Abdolhamid Alizadeh*Hadis Afshar Hezarkhani

Affiliation:

• Department of Organic Chemistry, Razi University, Kermanshah 67149-67346,Iran

• Department of Organic Chemistry, Razi University, Kermanshah 67149-67346,Iran

Keywords: Substituted phenols, hexaphenyloxodiphosphonium triflate, hydroxylation, hydrogen peroxide, arene.

Abstract: A mild and efficient protocol for the synthesis of phenols from arenes has been developed using aqueous hydrogen peroxide as an oxidizing agent and hexaphenyloxodiphosphonium triflate as a promoter. The reactions were carried out with the simple procedure in EtOH-H2O at room temperature in short reaction times.

Cite this article as:

Khodaei Mehdi Mohammad *, Alizadeh Abdolhamid *, Hezarkhani Afshar Hadis , Synthesis of Substituted Phenols via Hydroxylation of Arenes Using Hydrogen Peroxide in the Presence of Hexaphenyloxodiphosphonium Triflate, Letters in Organic Chemistry 2018; 15 (10) . https://dx.doi.org/10.2174/1570178615666180430121524