Abstract
Background: Cartilage injury has always been puzzled for clinicians. The treatments used clinically for cartilage injury usually bring about fibrocartilage. The emergence of tissue engineering lights up the hope of cartilage repair.
Objective: This review will sum up the existing learnings about electrospun fibers, revolving about the electrospinning materials, micromorphology, improvements and electrospun technologies newly developed in cartilage repair and regeneration.
Results: Electrospun fibers as scaffolds for cartilage regeneration have been one of researching hotspots for years. The studies about new electrospun materials and new electrospinning technologies greatly promoted the development of this field.
Conclusion: Electrospun fibers have showed great potential in cartilage regeneration. But there is still a long way to go before clinical application. The material embellishment and structure imitation should be highlighted in future.
Keywords: Electrospun, tissue engineering, electrospinning materials, stem cell, biomaterials, cartilage.
Current Stem Cell Research & Therapy
Title:Electrospun Fibers for Cartilage Tissue Regeneration
Volume: 13 Issue: 7
Author(s): Guo Li, Sirong Shi, Shiyu Lin, Tengfei Zhou, Xiaoru Shao, Qiao Huang, Bofeng Zhu and Xiaoxiao Cai*
Affiliation:
- State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu,China
Keywords: Electrospun, tissue engineering, electrospinning materials, stem cell, biomaterials, cartilage.
Abstract: Background: Cartilage injury has always been puzzled for clinicians. The treatments used clinically for cartilage injury usually bring about fibrocartilage. The emergence of tissue engineering lights up the hope of cartilage repair.
Objective: This review will sum up the existing learnings about electrospun fibers, revolving about the electrospinning materials, micromorphology, improvements and electrospun technologies newly developed in cartilage repair and regeneration.
Results: Electrospun fibers as scaffolds for cartilage regeneration have been one of researching hotspots for years. The studies about new electrospun materials and new electrospinning technologies greatly promoted the development of this field.
Conclusion: Electrospun fibers have showed great potential in cartilage regeneration. But there is still a long way to go before clinical application. The material embellishment and structure imitation should be highlighted in future.
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Cite this article as:
Li Guo , Shi Sirong , Lin Shiyu , Zhou Tengfei , Shao Xiaoru , Huang Qiao , Zhu Bofeng and Cai Xiaoxiao *, Electrospun Fibers for Cartilage Tissue Regeneration, Current Stem Cell Research & Therapy 2018; 13 (7) . https://dx.doi.org/10.2174/1574888X13666180417120508
DOI https://dx.doi.org/10.2174/1574888X13666180417120508 |
Print ISSN 1574-888X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3946 |
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