Synthesis of Quinoxaline-Based Compounds and Their Antitumor and Antiviral Potentials

Title:Synthesis of Quinoxaline-Based Compounds and Their Antitumor and Antiviral Potentials

Volume: 15 Issue: 3

Author(s): Jelena Petronijevic*, Nenad Jankovic and Zorica Bugarcic

Affiliation:

• Department of Chemistry, Faculty of Science, University of Kragujevac, Kragujevac,Serbia

Keywords: o-Phenylenediamine, Diketo acid, quinoxaline, antitumor activity, antiviral activity, benzodiazepene.

Abstract: Background: Quinoxaline-based derivatives present a group of very important heterocyclic pharmacophores which occupied the attention of a large number of scientists in the last few decades. Compounds with quinoxaline fragment have significant antitumor and antiviral potential, proved by an in vitro or/and in vivo study, and possess therapeutic potential.

Conclusion: In this review article, we present an overview of the developments in the area of synthesis of compounds that contain quinoxaline scaffold with antitumor or antiviral activities.

Cite this article as:

Petronijevic Jelena *, Jankovic Nenad and Bugarcic Zorica , Synthesis of Quinoxaline-Based Compounds and Their Antitumor and Antiviral Potentials, Mini-Reviews in Organic Chemistry 2018; 15 (3) . https://dx.doi.org/10.2174/1570193X14666171201143357