Abstract
Background: Nanotechnology has demonstrated great potential for the cure of bone infections through the development of antibacterial nanomaterials. The bone diseases include many skeletal- related illnesses such as arthritis, bone cancer, osteosarcoma and osteoarthritis, which are the major causes of mortality in human beings. Moreover, there are no effective treatment strategies available for such bone diseases. However, these limitations create pressing need to search safe and efficient novel drugs for clinical treatments. In this context, nanotechnology- based targeted drug delivery is widely proposed as an effective treatment strategy.
Objective: Recently, various nanomaterials have been extensively used in the management of bone diseases. Therefore, we aimed to write a comprehensive review on the role of nanotechnology in bone diseases.
Methods: We searched Google and PubMed portals extensively concerning literature of the following subjects so as to get latest updated information related to current developments in the field of nanotechnology in the context of bone diseases.
Results: In the present review, we have discussed the role of the various nanomaterials, which can be promisingly used in the diagnosis and treatment of dentistry and bone cancer. Further, biomedical applications of nanomaterials like imaging, diagnostic, drug delivery and their use as regenerative bone substitutes have also been discussed.
Conclusions: Considering the recent advances in the field, it can be concluded that the development of nano-based approaches can be possible, which will play important role in the diagnosis and treatment of bone diseases, bone regeneration, and tissue reconstruction.
Keywords: Nanotechnology, nanomaterials, bone diseases, regenerative, medicine, dentistry.
Graphical Abstract
Call for Papers in Thematic Issues
Role of nanomaterials in fabrication of coatings, Machining and Joining
The application of nanoscience has brought about a revolution in the field of mechanical engineering by providing novel materials, boosting manufacturing processes, and generating cutting-edge products. The purpose of this special issue is to investigate the enormous impact that nanoscience has had on mechanical engineering, with a particular emphasis on ...read more
Advanced Inorganic Nanocomposites and Their Emerging Applications
This special issue collection will highlight developments on the recent trends about the synthesis of metal oxides, nanoclusters, biomaterials, 2D nanomaterials, nanocrystals, nanocomposites, etc. and their applications in electrochemical systems, tissue regeneration, energy storage and harvesting, sensors, etc. The novelty of the methods in the chemical synthesis and their characterizations, ...read more
Applicability of Nanotechnology for Performance Enhancement of Clean Energy Technologies
Population growth, industrialization, and improvement in living quality would lead to further increase in energy demand in near future. Regarding the disadvantages of fossil fuels such as fluctuations in their price, high emissions of greenhouse gases and restriction of their sources, it is crucial to use and exploit alternative energy ...read more
Graphene and 2D Materials for Energy Storage and Conversion
This thematic issue will discuss the recent advances in graphene-based nanomaterials for different energy technologies. Graphene possesses a high surface area, and stable structure and exhibits many interesting electronic, optical, and mechanical properties due to its 2D crystal structure. Graphene is of both fundamental interest and suitable for a wide ...read more
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