Abstract
Background: Microwave irradiation has emerged as a useful synthetic strategy for chemists and drug developers due to enhanced yields, regioselectivity, and faster reaction times. One area of importance in its practice has been the design of spiro compounds, which possess great interest on account of their natural occurrence and medicinal capabilities. The increasingly large number of these scaffolds and unlimited amount of methodologies utilized in their preparation have made them good candidates for the microwave assisted approach.
Conclusion: Therefore, this review emphasizes the use of microwave irradiation in the synthesis of spiro heterocyclic compounds.
Keywords: Spiro compounds, heterocycles, microwave, green synthesis.
Current Organic Chemistry
Title:Microwave Assisted Synthesis of Spiro Heterocyclic Systems: A Review
Volume: 22 Issue: 1
Author(s): Pankaj Khanna, Leena Khanna, Sean J. Thomas, Abdullah M. Asiri and Siva S. Panda*
Affiliation:
- Department of Chemistry & Physics, Augusta University, Augusta, Georgia 30912,United States
Keywords: Spiro compounds, heterocycles, microwave, green synthesis.
Abstract: Background: Microwave irradiation has emerged as a useful synthetic strategy for chemists and drug developers due to enhanced yields, regioselectivity, and faster reaction times. One area of importance in its practice has been the design of spiro compounds, which possess great interest on account of their natural occurrence and medicinal capabilities. The increasingly large number of these scaffolds and unlimited amount of methodologies utilized in their preparation have made them good candidates for the microwave assisted approach.
Conclusion: Therefore, this review emphasizes the use of microwave irradiation in the synthesis of spiro heterocyclic compounds.
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Cite this article as:
Khanna Pankaj , Khanna Leena , Thomas J. Sean, Asiri M. Abdullah and Panda S. Siva *, Microwave Assisted Synthesis of Spiro Heterocyclic Systems: A Review, Current Organic Chemistry 2018; 22 (1) . https://dx.doi.org/10.2174/1385272821666170818161517
DOI https://dx.doi.org/10.2174/1385272821666170818161517 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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