Gene Delivery with Organic Electronic Biomaterials

Author(s): Kathryn F.A. Clancy, John G. Hardy*.

Journal Name: Current Pharmaceutical Design

Volume 23 , Issue 24 , 2017

Abstract:

Gene therapy may be capable of treating a variety of diseases, a prerequisite of which is the successful delivery of polynucleic acids (e.g., DNA, RNA) to a patient’s cells. Delivery can be achieved technologically (e.g., using electroporation), using viruses (natural gene delivery vectors) or non-viral vectors (e.g., lipids, nanoparticles, polymers). This article aims to give the reader an overview of the use of organic electronic materials (i.e., fullerenes, graphenes and conjugated polymers) as non-viral gene delivery vectors.

Keywords: Organic electronics, carbon nanotubes, fullerene, graphene, conjugated polymer, gene delivery, gene therapy, biodegradable.

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Article Details

VOLUME: 23
ISSUE: 24
Year: 2017
Page: [3614 - 3625]
Pages: 12
DOI: 10.2174/1381612823666170710124137
Price: $58

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