Abstract
This mini review provides a short overview of the main methods of the selection and analysis of the circulating tumor cells. We briefly focus on the evolution of the technical approaches used in the CTCs analysis from early description of the most discussed contemporary workflows such as Cellsearch and CTC-iChip. In addition, we discuss more “unconventional” approaches such as mass spectrometry and NMR based methods of CTC analysis.
Keywords: Circulating tumor cells, CTC cluster, breast cancer, prostate cancer, detection of CTCs, Cellsearch.
Current Pharmaceutical Design
Title:Current Methods of the Circulating Tumor Cells (CTC) Analysis: A Brief Overview
Volume: 23 Issue: 32
Author(s): Natalia Dementeva, Daria Kokova and Oleg A. Mayboroda*
Affiliation:
- Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden,Netherlands
Keywords: Circulating tumor cells, CTC cluster, breast cancer, prostate cancer, detection of CTCs, Cellsearch.
Abstract: This mini review provides a short overview of the main methods of the selection and analysis of the circulating tumor cells. We briefly focus on the evolution of the technical approaches used in the CTCs analysis from early description of the most discussed contemporary workflows such as Cellsearch and CTC-iChip. In addition, we discuss more “unconventional” approaches such as mass spectrometry and NMR based methods of CTC analysis.
Export Options
About this article
Cite this article as:
Dementeva Natalia , Kokova Daria and Mayboroda A. Oleg *, Current Methods of the Circulating Tumor Cells (CTC) Analysis: A Brief Overview, Current Pharmaceutical Design 2017; 23 (32) . https://dx.doi.org/10.2174/1381612823666170616082608
DOI https://dx.doi.org/10.2174/1381612823666170616082608 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
The Histone Deacetylase Inhibitor, MS-275 (Entinostat), Downregulates c-FLIP, Sensitizes Osteosarcoma Cells to FasL, and Induces the Regression of Osteosarcoma Lung Metastases
Current Cancer Drug Targets Psychoimmunological Analysis of Cancer Patients: Correlation with the Prognosis
Current Aging Science Role of microRNAs in Gynecological Pathology
Current Medicinal Chemistry Tumor-dependent Effects of Proteoglycans and Various Glycosaminoglycan Synthesizing Enzymes and Sulfotransferases on Patients’ Outcome
Current Cancer Drug Targets RANKL/RANK/OPG: Key Therapeutic Target in Bone Oncology
Current Drug Discovery Technologies Curcumin Conjugates and Metallocomplexes as Lead Compounds for Development of Anticancer Agents - A Short Review
Current Bioactive Compounds Preterm Birth and the Risk of Neurodevelopmental Disorders - Is There a Role for Epigenetic Dysregulation?
Current Genomics Anti-HER2 Therapy in Elderly Breast Cancer Patients
Reviews on Recent Clinical Trials Hypoxia-inducible Factor (HIF) in Hormone Signaling During Health and Disease
Cardiovascular & Hematological Agents in Medicinal Chemistry Evaluation of the Risk/Benefit Ratio of Old and New Anti-Inflammatory Drugs
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Effects of Peptidic Antagonists of Grb2-SH2 on Human Breast Cancer Cells
Protein & Peptide Letters A Review on Chemical Profile of Coumarins and their Therapeutic Role in the Treatment of Cancer
Current Drug Delivery Stem Cells Therapies in Basic Science and Translational Medicine: Current Status and Treatment Monitoring Strategies
Current Pharmaceutical Biotechnology How Much is Enough? Modulation of Dose-Response Curve for Steroid Receptor-Regulated Gene Expression by Changing Concentrations of Transcription Factor
Current Topics in Medicinal Chemistry Dysregulation of SIRT-1 Signaling in Multiple Sclerosis and Neuroimmune Disorders: A Systematic Review of SIRTUIN Activators as Potential Immunomodulators and their Influences on other Dysfunctions
Endocrine, Metabolic & Immune Disorders - Drug Targets Recent Progress in Synthesis and Applications of Fluorinated Carbohydrates
Current Organic Chemistry Effect of Salinomycin on Expression Pattern of Genes Associated with Apoptosis in Endometrial Cancer Cell Line
Current Pharmaceutical Biotechnology Cancer Stem Cells: How can we Target them?
Current Medicinal Chemistry Clinical Features of Scleroderma-Like Disorders: A Challenge for the Rheumatologist
Current Rheumatology Reviews Obesity and Metabolic Syndrome Affect the Cholinergic Transmission a nd Cognitive Functions
CNS & Neurological Disorders - Drug Targets