Abstract
Background and Objective: Urtica dioica (stinging nettle), a member of the Urticaceae family, has been used in various traditional systems of medicines since ancient times especially for joint pain, arthritis and prostate problems. Its roots and leaves contain a wide variety of bioactive constituents like sterols, fatty acids, lectins terpenes, phenylpropanes, lignans and coumarins. The leaves and root extract shows various activities like hypoglycemic, anti-inflammatory, antiproliferative, antioxidant, hypolipemic, antirheumatic, anticarcinogenic and antiviral activity. It shows its effects through the inhibition of aromatase, 5 α-reductase, cell proliferation and Na+, K+-ATPase inhibition.
Conclusion: The article reviews the phytochemistry and phytopharmacology of the plant.
Keywords: Alopecia, analgesic, anti-arthritic, antihypertensive, anti-inflammatory, 5 alpha reductase inhibitor, BPH, herbal remedy, nettle, urtica.
Current Traditional Medicine
Title:A Comprehensive Review on Phytochemistry and Pharmacological Effects of Stinging Nettle (Urtica dioica)
Volume: 3 Issue: 3
Author(s): Mona Semalty, Lokesh Adhikari, Divya Semwal, Anita Chauhan, Akash Mishra, Rupali Kotiyal and Ajay Semalty*
Affiliation:
- Department of Pharmaceutical Sciences, H.N.B. Garhwal (Central) University Srinagar (Garhwal)-246174, Uttarakhand,India
Keywords: Alopecia, analgesic, anti-arthritic, antihypertensive, anti-inflammatory, 5 alpha reductase inhibitor, BPH, herbal remedy, nettle, urtica.
Abstract: Background and Objective: Urtica dioica (stinging nettle), a member of the Urticaceae family, has been used in various traditional systems of medicines since ancient times especially for joint pain, arthritis and prostate problems. Its roots and leaves contain a wide variety of bioactive constituents like sterols, fatty acids, lectins terpenes, phenylpropanes, lignans and coumarins. The leaves and root extract shows various activities like hypoglycemic, anti-inflammatory, antiproliferative, antioxidant, hypolipemic, antirheumatic, anticarcinogenic and antiviral activity. It shows its effects through the inhibition of aromatase, 5 α-reductase, cell proliferation and Na+, K+-ATPase inhibition.
Conclusion: The article reviews the phytochemistry and phytopharmacology of the plant.
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Cite this article as:
Semalty Mona, Adhikari Lokesh, Semwal Divya , Chauhan Anita , Mishra Akash , Kotiyal Rupali and Semalty Ajay*, A Comprehensive Review on Phytochemistry and Pharmacological Effects of Stinging Nettle (Urtica dioica), Current Traditional Medicine 2017; 3 (3) . https://dx.doi.org/10.2174/2215083803666170502120028
DOI https://dx.doi.org/10.2174/2215083803666170502120028 |
Print ISSN 2215-0838 |
Publisher Name Bentham Science Publisher |
Online ISSN 2215-0846 |
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