Abstract
Skin is the most suitable and recommendable organ of the human body for topical administration and the main route for topical drug delivery system. Drug delivery system is the methodology used to ensure the entry of drugs into the body, reaching their target for pharmacological action. Patients tend to prefer the painless route for drug administration. So, pharmaceutical aerosols came to existence to meet patient compliance. Many variations in excipients with respect to compatibility to drugs, stability and economy are being used to improve the aerosol system of drug delivery. The present review deals with the excipients and constituents used in a pharmaceutical aerosol system as per target delivery.
Summary: The review deals with the excipients and constituents used in a pharmaceutical aerosol system as per target delivery.
Conclusion: Presently, aerosol drug delivery system has become beneficial as far as faster pharmacological action and economy are concerned. Other than the active pharmaceutical ingredient (API), the pharmacological action of the aerosol system is also dependent on the excipients used as they help the API to penetrate through the skin as fast as possible.
Keywords: Excipients, pharmaceutical aerosol, propellants, skin, solvents, topical drug delivery system.
Current Drug Delivery
Title:Importance of Propellants and Excipients in Pharmaceutical Topical Aerosol
Volume: 14 Issue: 8
Author(s): Maunab Patra*, Sibasis Bhattacharya and Meenakshi Patnaik
Affiliation:
- Abbess Healthcare OPC Pvt. Ltd., Kandivili East, Mumbai - 400101,India
Keywords: Excipients, pharmaceutical aerosol, propellants, skin, solvents, topical drug delivery system.
Abstract: Skin is the most suitable and recommendable organ of the human body for topical administration and the main route for topical drug delivery system. Drug delivery system is the methodology used to ensure the entry of drugs into the body, reaching their target for pharmacological action. Patients tend to prefer the painless route for drug administration. So, pharmaceutical aerosols came to existence to meet patient compliance. Many variations in excipients with respect to compatibility to drugs, stability and economy are being used to improve the aerosol system of drug delivery. The present review deals with the excipients and constituents used in a pharmaceutical aerosol system as per target delivery.
Summary: The review deals with the excipients and constituents used in a pharmaceutical aerosol system as per target delivery.
Conclusion: Presently, aerosol drug delivery system has become beneficial as far as faster pharmacological action and economy are concerned. Other than the active pharmaceutical ingredient (API), the pharmacological action of the aerosol system is also dependent on the excipients used as they help the API to penetrate through the skin as fast as possible.
Export Options
About this article
Cite this article as:
Patra Maunab *, Bhattacharya Sibasis and Patnaik Meenakshi, Importance of Propellants and Excipients in Pharmaceutical Topical Aerosol, Current Drug Delivery 2017; 14 (8) . https://dx.doi.org/10.2174/1567201814666170309104245
DOI https://dx.doi.org/10.2174/1567201814666170309104245 |
Print ISSN 1567-2018 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5704 |
Call for Papers in Thematic Issues
Advances of natural products, bio-actives and novel drug delivery system against emerging viral infections
Due to the increasing prevalence of viral infections and the ability of these human pathogens to develop resistance to current treatment strategies, there is a great need to find and develop new compounds to combat them. These molecules must have low toxicity, specific activity and high bioavailability. The most suitable ...read more
Electrospun Fibers as Drug Delivery Systems
In recent years, electrospun fibers have attracted considerable attention as potential platforms for drug delivery due to their distinctive properties and adaptability. These fibers feature a notable surface area-to-volume ratio and can be intentionally designed with high porosity, facilitating an increased capacity for drug loading and rendering them suitable for ...read more
Emerging Nanotherapeutics for Mitigation of Neurodegenerative Disorders
Conditions affecting the central nervous system (CNS) present a significant hurdle due to limited access of both treatments and diagnostic tools for the brain. The blood-brain barrier (BBB) acts as a barrier, restricting the passage of molecules from the bloodstream into the brain. The most formidable challenge facing scientists is ...read more
Nanotechnology Based Chemotherapy for the treatment of Head & Neck Cancer
The escalating recurrence rates observed in Head and Neck cancer, particularly within the chemo-therapeutically treated cohort (50-60%), can be attributed to the non-selective nature of current anticancer drug delivery modalities. In this context, nanotechnology-based drug delivery systems emerge as a promising avenue for achieving precise localization of therapeutic agents to ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Role of Psychiatrists in the Diagnosis and Management of Alzheimer's Disease “Revisited”: A Review and Clinical Opinion
Current Psychiatry Reviews Ultrasonographic Applications in the Thorax
Current Medical Imaging Associations of Plasma BACE1 Level and BACE1 C786G Gene Polymorphism with Cognitive Functions in Patients with Type 2 Diabetes: A Cross- Sectional Study
Current Alzheimer Research Recent Developments in Temperature Responsive Shape Memory Polymers
Mini-Reviews in Organic Chemistry Allergen-Induced Inflammation
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Mikuliczs Disease and its Extraglandular Lesions
Current Immunology Reviews (Discontinued) The Tetrahydroisoquinoline Scaffold in ABC Transporter Inhibitors that Act as Multidrug Resistance (MDR) Reversers
Current Topics in Medicinal Chemistry Effect of Resveratrol and Tiron on the Inactivation of Glyceraldehyde-3- phosphate Dehydrogenase Induced by Superoxide Anion Radical
Current Medicinal Chemistry Eight-Year Follow-Up of an Initial Case with NF-κB Decoy Oligodeoxynucleotide Transfection After Coronary Stent Implantation
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) Vaccination and Antiviral Treatment of Neglected Diseases Caused by Flaviviral Infections
Current Medicinal Chemistry Vitamin D and Cardiovascular Disease
Current Vascular Pharmacology Molecular Design, Synthesis and Evaluation of 2,3-Diarylquinoxalines as Estrogen Receptor Ligands
Medicinal Chemistry NINJ2 Gene Polymorphisms and Susceptibility to Ischemic Stroke: An Updated Meta-Analysis
Current Neurovascular Research Targeting Dyslipidemia in the Metabolic Syndrome: An Update
Current Vascular Pharmacology Potential of Selected Indian Herbs for COVID-19
Current Traditional Medicine Immunology and Epilepsy: Clinical and Experimental Evidence
Current Immunology Reviews (Discontinued) Inflammatory Mechanisms of Adverse Reactions to BMS
Current Vascular Pharmacology Pharmacogenetics of Angiotensin-Converting Enzyme Inhibitors in Patients with Alzheimer's Disease Dementia
Current Alzheimer Research Rational Design and Development of RDP58
Current Pharmaceutical Design Hypertension and Childhood Obesity: A Whirling Tango. A Review of the Dance Steps
Current Hypertension Reviews