Abstract
Objective: In the present study, the essential oil of Athroisma proteiformis was characterized for the first time.
Method: GC-HRMS (Gas Chromatography-High Resolution Mass Spectrometry) was performed for qualitative and quantitative analysis of the phytochemicals present in the extract. Chemical analyses were conducted to evaluate the total phenols, total flavonoids and antioxidant activity of the extract. Results: Of the 130 peaks detected, 50 were studied and 30 compounds were clearly identified. The main components of the extract were p-cymen-8-ol, the major compound (13.37%), followed by caryophyllene oxide (12.02%), o-cymene (7.79%), humulene epoxide II (7.62%) and limonene (7.35%). The essential oil of Athroisma proteiformis exhibited a good antioxidant activity. The Athroisma extract IC50 values were lower than those of the antioxidant standards used in the FRAP and ABTS tests, ascorbic acid and BHT, and lower than glutathione in the OH radical reducing power test. On the contrary, in the DPPH test, IC50 was higher for A. proteiformis than for ascorbic acid or BHT. Conclusion: It can be concluded that the A. proteiformis plant can be used as a source of natural antioxidants but the consequences on human health should first be carefully studied due to the large number of compounds present in the oil.Keywords: Antioxidant activity, Asteraceae, Athroisma proteiformis, caryophyllene oxide, essential oil, p-Cymen-8-ol.
The Natural Products Journal
Title:Chemical Characterization and Antioxidant Potential of Athroisma proteiformis Essential Oil
Volume: 7 Issue: 3
Author(s): Claudine Aimée Rasolohery, Boniface Erménegilde Ralaibia, Alicia Ayerdi Gotor, Franck Merlier, Rakotonirina Benja, Marcelle Rakotovao and Larbi Rhazi*
Affiliation:
- UniLaSalle BP 30313, Beauvais CEDEX,France
Keywords: Antioxidant activity, Asteraceae, Athroisma proteiformis, caryophyllene oxide, essential oil, p-Cymen-8-ol.
Abstract: Objective: In the present study, the essential oil of Athroisma proteiformis was characterized for the first time.
Method: GC-HRMS (Gas Chromatography-High Resolution Mass Spectrometry) was performed for qualitative and quantitative analysis of the phytochemicals present in the extract. Chemical analyses were conducted to evaluate the total phenols, total flavonoids and antioxidant activity of the extract. Results: Of the 130 peaks detected, 50 were studied and 30 compounds were clearly identified. The main components of the extract were p-cymen-8-ol, the major compound (13.37%), followed by caryophyllene oxide (12.02%), o-cymene (7.79%), humulene epoxide II (7.62%) and limonene (7.35%). The essential oil of Athroisma proteiformis exhibited a good antioxidant activity. The Athroisma extract IC50 values were lower than those of the antioxidant standards used in the FRAP and ABTS tests, ascorbic acid and BHT, and lower than glutathione in the OH radical reducing power test. On the contrary, in the DPPH test, IC50 was higher for A. proteiformis than for ascorbic acid or BHT. Conclusion: It can be concluded that the A. proteiformis plant can be used as a source of natural antioxidants but the consequences on human health should first be carefully studied due to the large number of compounds present in the oil.Export Options
About this article
Cite this article as:
Rasolohery Aimée Claudine, Ralaibia Erménegilde Boniface, Gotor Ayerdi Alicia, Merlier Franck, Benja Rakotonirina, Rakotovao Marcelle and Rhazi Larbi*, Chemical Characterization and Antioxidant Potential of Athroisma proteiformis Essential Oil, The Natural Products Journal 2017; 7 (3) . https://dx.doi.org/10.2174/2210315507666170102154445
DOI https://dx.doi.org/10.2174/2210315507666170102154445 |
Print ISSN 2210-3155 |
Publisher Name Bentham Science Publisher |
Online ISSN 2210-3163 |
Call for Papers in Thematic Issues
Ayurvedic medicinal therapeutic approaches for inflammatory and neurodegenerative disorders
Usually, in our elderly population, neurodegenerative disorders occur due to neuron death. Alzheimer?s disease (AD) is an irreversible and progressive neurodegenerative disease. Dementia is the leading cause of AD, which affects about 30 million people worldwide. According to the World Alzheimer report 2018, a new case of dementia develops every ...read more
Recent Advances in Biotransformation of Bioactive Terpenoids using Aspergillus niger
Biotransformation is the reaction catalyzed by biological catalysts of either isolated enzymes or whole cell cultures of microorganisms. This process has been extensively applied in the conversion of bioactive terpenoids with high regio- and stereospecifity. This process has been also applied in the lead discovery and development. Aspergillus niger has ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Intestinal Immunomodulation. Role of Regulative Peptides and Promising Pharmacological Activities
Current Pharmaceutical Design Synthesis and Characterization of Two New Thiophene Acetyl Salicylic Acid Esters and their ortho- and para-effect on Anticancer Activity
Anti-Cancer Agents in Medicinal Chemistry Biomedical Applications of Protein Microarrays
Current Medicinal Chemistry Update on the Development of microRNA and siRNA Molecules as Regulators of Cell Physiology
Recent Patents on DNA & Gene Sequences Open Source Software and Web Services for Designing Therapeutic Molecules
Current Topics in Medicinal Chemistry Mutant Cell Surface Receptors as Targets for Individualized Cancer Diagnosis and Therapy
Current Cancer Drug Targets Chemosensitization and Immunosensitization of Resistant Cancer Cells to Apoptosis and Inhibition of Metastasis by the Specific NF-κB Inhibitor DHMEQ
Current Pharmaceutical Design Phytochemicals Resveratrol and Sulforaphane as Potential Agents for Enhancing the Anti-Tumor Activities of Conventional Cancer Therapies
Current Pharmaceutical Biotechnology Down-Regulation of DDR1 Induces Apoptosis and Inhibits EMT through Phosphorylation of Pyk2/MKK7 in DU-145 and Lncap-FGC Prostate Cancer Cell Lines
Anti-Cancer Agents in Medicinal Chemistry Recent Advances in Liposomal Drug Delivery: A Review
Pharmaceutical Nanotechnology C-KIT Signaling in Cancer Treatment
Current Pharmaceutical Design Monoclonal Antibodies as Cancer Therapeutics
Recent Patents on Biotechnology Intraperitoneal Oncolytic and Tumor Vaccination Therapy with Replication-Competent Recombinant Virus: The Herpes Paradigm
Current Gene Therapy A Discussion of MicroRNAs in Cancers
Current Bioinformatics Adverse Effects of Statins - Mechanisms and Consequences
Current Drug Safety Targeting ATP7A to Increase the Sensitivity of Neuroblastoma Cells to Retinoid Therapy
Current Cancer Drug Targets A Hemagglutinin from Northeast Red Beans with Immunomodulatory Activity and Anti-proliferative and Apoptosis-inducing Activities Toward Tumor Cells
Protein & Peptide Letters PRL-3, An Emerging Marker of Carcinogenesis, Is Strongly Associated with Poor Prognosis
Anti-Cancer Agents in Medicinal Chemistry Applications of Micro/Nanotechnology in Ultrasound-based Drug Delivery and Therapy for Tumor
Current Medicinal Chemistry Radiation Oncology and Molecular-Targeted Therapy for EGFR and its Signal Transduction Pathways: Molecular Basis and Clinical Application for Improvement of Radiotherapeutic Outcomes
Current Signal Transduction Therapy