Abstract
Throughout the development of medicine, the spotlight has been held by the search for new drugs blocking different types of arrhythmia. In the past decade, much attention was given to the selection of active antiarrhythmic substances from plant material. It has been shown that these compounds have a good antiarrhythmic effect, and their chemical modifications substantially increase their major effects while adding other beneficial pharmacological properties. In this regard, work on the chemical modification of plant-source antiarrhythmics is highly relevant to the development of new and promising drugs.
Keywords: Antiarrhythmic drugs, cardiovascular, chemical modifications, ischemic heart disease, plant substances, thyreoidea.
Mini-Reviews in Medicinal Chemistry
Title:Natural Products as a Source of Antiarrhythmic Drugs
Volume: 18 Issue: 4
Author(s): Arkadiy O. Bryzgalov*, Tatjana G. Tolstikova, Elvira E. Shults and Kristina O. Petrova
Affiliation:
- Novosibirsk Institute of Organic Chemistry, Siberian Branch of Russian Academy of Sciences, 9 Prosp. Akad. Lavrentyeva, Novosibirsk 630090,Russian Federation
Keywords: Antiarrhythmic drugs, cardiovascular, chemical modifications, ischemic heart disease, plant substances, thyreoidea.
Abstract: Throughout the development of medicine, the spotlight has been held by the search for new drugs blocking different types of arrhythmia. In the past decade, much attention was given to the selection of active antiarrhythmic substances from plant material. It has been shown that these compounds have a good antiarrhythmic effect, and their chemical modifications substantially increase their major effects while adding other beneficial pharmacological properties. In this regard, work on the chemical modification of plant-source antiarrhythmics is highly relevant to the development of new and promising drugs.
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Cite this article as:
Bryzgalov O. Arkadiy*, Tolstikova G. Tatjana, Shults E. Elvira and Petrova O. Kristina, Natural Products as a Source of Antiarrhythmic Drugs, Mini-Reviews in Medicinal Chemistry 2018; 18 (4) . https://dx.doi.org/10.2174/1389557516666161104144815
DOI https://dx.doi.org/10.2174/1389557516666161104144815 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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