Abstract
Background: The chemistry of tetrazine has gained an increased attention in the last decades due to their applications materials science and coordination chemistry. 1,3-Dipolar cycloaddition of nitrile imines to C60 is the standard method for annelating the pyrazoline ring to the fullerene sphere. The interest in the chemistry of hydrazonoyl halides is a consequence of the fact that they undergo a wide variety of reactions, which provide routes heterocyclic compounds.
Results: A facile synthesis of polytetrazines based on bishydrazonoyl halides is described. Bis(pyrazolino[60] fullerenes) were synthesized from the reaction of bishydrazonoyl halides with [60]fullerene. Moreover, an efficient synthesis of new polypyrazoline-maleimide is reported. The synthetic methods involves 1,3-dipolar cycloaddition reactions of bisnitrilimines (generated in situ by the effect of the triethylamine on bishydrazonoyl halides) to give the final products. Structures of the newly synthesized products were elucidated via elemental analyses and spectral data (FT-IR, MS, 1H and 13C NMR). Conclusion: Novel heterocycles of polytetrazines, bis(pyrazolino[60]fullerenes) and Polypyrazoline-maleimide based on 1,3-dipolar cycloaddition reaction are reported.Keywords: Bishydrazonyl halides, 1, 3-dipolar cycloaddition, polytetrazines, pyrazoles.
Graphical Abstract
Call for Papers in Thematic Issues
Exploring the Role of Chemical Graph Theory in Advancing Current Organic Synthesis
Organic synthesis is a fundamental discipline in chemistry, crucial for the creation of complex molecules with diverse applications in pharmaceuticals, materials science, and beyond. However, the process of designing efficient synthetic routes for target molecules remains challenging. Chemical graph theory, a branch of theoretical chemistry, offers powerful tools for understanding ...read more
Photoswitches for Molecular Recognition
This Special Issue would cover the hot topics on synthesis and chemical and photophysical characterization of new photoswitchable derivatives and their applications on molecular recognition of metabolites and biological active compounds, both in physiological medium and in living cells. Photoswitches are compounds that can change their conformation or properties in ...read more
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